Collected Dataset / SHCS_Followup_63

The population is composed of HIV-infected adult (aged 18 years old or more) individuals living in Switzerland or having regular visits at a Swiss outpatient clinic or private physician of seven cohort centres (in Basel, Bern, Geneva, Lausanne and Zurich, and two cantonal hospitals, St Gallen and Ticino).

Information concerning participant's source of income, physical activity, smoking, hospitalizations, family situation, household structure, sexual behaviors, alcohol consumption, drugs use, pregnancy, contraception, obstetric event, medication protocol, vaccination (PneumoVACC), biopsy, fibroscan, influenza, fracture, depression (diagnostic tool), perception on cognition and disease relapse were collected during a visit to the physician. Information on opportunistic diseases of HIV infection and on serious non-opportunistic infection (SNOI), sexually transmitted disease (STD), Immune Reconstitution Inflammatory Syndrome (IRIS), diagnosis of cancer (anal cancer screening), myocardial infarction, stroke, diabetes and lipodystrophy or other clinical events were also collected and reported by the physician. Detailed information was collected concerning antiretroviral treatment: dosage, in case of treatment interruption, the reason of withdrawal, adherence, is also assessed. Information on undergone gynecological examination and performed cervical smear were collected on a gynecological form. Weight, height, blood pressure as well as waist and hip circumference were measured during the visit. Bone densitometry was measured using dual energy X-ray absorptiometry (DEXA). A spectrum of laboratory analysis was collected from blood samples. This included HIV-2 Viral load, leucocyte and lymphocyte counts (CD3, CD4 and CD8 cell counts included), hemoglobin and platelets; cholesterol, HDL cholesterol, triglyceride, glucose and lactate concentrations. Presence of Hepatitis B and C (qualitative and quantitative tests, viral load) and syphilis were screened. A tuberculin skin reactivity test was performed. For patients under antiretroviral treatment, ALAT, ASAT, alkaline phosphatase and creatinine levels were measured and a HIV drug resistance test performed. Laboratory data were obtained from transfer from hospital databases.