NHS II
The population is composed of registered nurses aged 25 to 42 years at recruitment in 1989 living in California, Connecticut, Indiana, Iowa, Kentucky, Massachusetts, Michigan, Missouri, New York, North Carolina, Ohio, Pennsylvania, South Carolina and Texas.
The population is composed of registered nurses aged 25 to 42 years at recruitment in 1989 living in California, Connecticut, Indiana, Iowa, Kentucky, Massachusetts, Michigan, Missouri, New York, North Carolina, Ohio, Pennsylvania, South Carolina and Texas.
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Sex
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Women
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Minimum age
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25
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Maximum age
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42
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Newborns
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Twins
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Countries
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Territory
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California, Connecticut, Indiana, Iowa, Kentucky, Massachusetts, Michigan, Missouri, New York, North Carolina, Ohio, Pennsylvania, South Carolina and Texas.
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Ethnic Origin
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Health Status
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Other Criteria
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Primarily premenopausal women (mainly Caucasian) who had no history of cancer were included in the study population.
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Sources of recruitment
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Specific Population
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Members of an association
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Supplementary Information
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Eligible participants were recruited through the American Nurses' Association data. Nurses who responded to the first mailed questionnaires were comprised in the cohort.
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Participants from Existing Studies
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Number of Participants
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116,429
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Number of Participants with Biological Samples
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Supplementary Information about selection criteria
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1996-99 blood and urine samples: 29,611 participants (18,521 women gave a blood sample in the early follicular phase and a blood and urine sample in the mid-luteal phase of the menstrual cycle)
2006-08 cheek cells samples: 29,859 participants
2010-12 blood and urine samples: 17,275 participants