Maelstrom Research Staging | CoLaus_PsyCoLaus_First_degree_relatives_Psychiatric_evaluation_followup

CoLaus_PsyCoLaus_First_degree_relatives_Psychiatric_evaluation_followup_2

Networks -

Variables -

Associated study CoLaus|PsyCoLaus Contingency Table

Population

CoLaus|PsyCoLaus - First-degree Relatives

The population is composed of adult first-degree relatives (biological parents and siblings) of the probands.

Selection Criteria

Minimum age

Newborns

Twins

Territory

Ethnic Origin

Health Status

Other Criteria

Recruitment

Sources of recruitment

General population

General Population

Selected sample

Supplementary Information

During the psychiatric evaluations between 2007 and 2012, all participants (probands) from the original cohort (probands) were systematically asked, whether they would allow the study to contact their first-degree relatives. If they agreed, written consent was requested for each relative in order to give the study permission to contact this person and to complete a brief self-report pedigree including the addresses and phone numbers of their relatives. These relatives were then invited by letter to participate. Those who agreed were contacted by a psychologist by phone, who provided further information on the study and sent them the detailed information letter and consent forms.

Number of Participants

Number of Participants

635

Number of Participants with Biological Samples

Supplementary Information about selection criteria

Parents: 219 participants

Siblings: 416 participants

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Data Collection Event

CoLaus|PsyCoLaus - First-degree Relatives - Psychiatric evaluation follow-up 2

Personality traits, attitudes, and functioning were assessed through a semi-structured diagnostic interview and a number of self-rating instruments. Diagnostic information was collected using the Diagnostic Interview for Genetic Studies (DIGS). Additional data was collected based on interview techniques, including headache symptoms (Diagnostic Interview for Headache Syndromes (DIHS)) and life events (F. Amiel-Lebigre interview). Complementary information on personality, temperamental features, social support, quality of life, job stress, and depression was obtained using a self-report battery including the following instruments: the State-Trait Anxiety Inventory (STAI), the Eysenck Personality Questionnaire (EPQ), the Hypomania Checklist-32 first revised version (HCL-32-R1), the Multidimensional Scale of Perceived Social Support (MSPSS), the Manchester Short Assessment of Quality of Life (MANSA), The Maastricht Vital Exhaustion Questionnaire (MVEQ), the Siegrist Job Stress Questionnaire, The Maslach Burnout Inventory (MBI), and a Depression screening (CES-D). Cognitive function was assessed using a diverse range of methodologies, including the Do 80 (Epreuve de dénomination orale d’images) Cognitive Complaint Questionnaire, the Grober and Buschke episodic memory test CERAD praxis items, the Lexical and semantic fluency tasks, the Stroop color test, and the Severity staging based on the Clinical Dementia Rating (CDR). This comprehensive approach ensured a thorough understanding of cognitive function in the study participants. Additional phenotypes included an EEG for abnormal functional connectivity and an MRI for brain morphology and noise measurements during sleep.

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Collected Dataset / CoLaus_PsyCoLaus_First_degree_relatives_Psychiatric_evaluation_followup_2

CoLaus_PsyCoLaus_First_degree_relatives_Psychiatric_evaluation_followup_2

Population

CoLaus|PsyCoLaus - First-degree Relatives

Data Collection Event

CoLaus|PsyCoLaus - First-degree Relatives - Psychiatric evaluation follow-up 2

Files

Variables Classifications