Collected Dataset / CAHHM_Enrollment

The population is composed of men and women aged 35-69 years, recruited from all participating cohorts of the Canadian Partnership for Tomorrow Project (CanPath), the Prospective Urban Rural Evaluation (PURE)-Canada cohort, and the Montreal Heart Institute (MHI) Biobank.

Detailed information on individuals’ cancer and cardiovascular risk factors, health behaviors’ including dietary assessment, physical fitness and smoking, and social factors, was obtained using questionnaires. Information about community factors (Individual Perception), immigration, acculturation, CVD related health services was collected. The CPTP Core Baseline Health and Lifestyle Questionnaire was also used to collect information. Measures of cognitive function using the Digit Symbol Substitution (DSS) test and the Montréal Cognitive Assessment (MoCA) were performed. Physical measures including: height, weight, percent body fat using the Tanita BIA machine, waist circumference, hip circumference, resting heart rate, and blood pressure were assessed. A standardized, comprehensive and cost-efficient multi-parametric MRI scan was attempted on all subjects. This includes the brain (ischemic white matter disease, covert strokes, cerebral atrophy and cerebral connectivity), the heart (morphology, volumes and mass, global and regional wall motion, pericardial fat, covert myocardial infarction, non-ischemic fibrosis, infiltration, perfusion and oxygenation), blood vessels (plaque volume) and the abdomen (visceral adipose tissue and liver fat). Urine and blood samples were collected. Participants’ cardiovascular and general health history, and vital status before enrollment was extracted from health care administrative databases through linkage of data.