Sydney Centenarian Study
- To determine the “cognitive profile” of exceptionally old individuals (95+ years, hereafter “centenarians”);
- To relate cognition in this age group to brain imaging parameters on MRI and to neuropathology in brain donors within the group;
- To examine centenarians from neuropsychiatric, medical, nutritional, and lifestyle perspectives to establish a “centenarian phenotype”; and
- To examine the determinants of “autonomy” in centenarians.
- Start Year
- 2009
Visit SCS
| Investigators | Contacts |
|---|---|
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Design
- Study design
- Cohort
- Follow Up
- Participants were followed up 6, 12 and 18 months after their baseline assessment.
- Supplementary Information
Marker Paper
Sachdev P., Levitan C., Crawford J., Sidhu M., Slavin M., Richmond R., Kochan N., Brodaty H., Wen W., Kang K., Mather K.A., Sydney Centenarian Study team. The Sydney Centenarian Study: Methodology And Profile Of Centenarians And Near-Centenarians. International Psychogeriatrics. 2013; 25(6): 993-1005.
PUBMED 23510643
Recruitment
- Recruitment Target
-
- Individuals
Number of Participants
- Number of Participants
- 345
- Number of Participants with Biological Samples
- 224
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
Timeline
SCS - Centenarians
Selection Criteria
- Minimum age
-
95
- Newborns
- Twins
- Countries
-
- Australia
- Territory
- Suburbs within the Randwick, Waverley, Woollahra, Botany Bay, Kogarah, Rockdale, and Marrickville local government areas in New South Wales.
- Ethnic Origin
-
- Health Status
-
- Supplementary Information about selection criteria
- People suffering from a terminal illness were excluded.
Recruitment
- Sources of recruitment
-
- General population
- Specific population
- Participants from existing studies
- General Population
-
- Volunteer enrolment
- Selected sample
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Individuals 95 years and older were recruited from seven electoral districts in Sydney using a multi-pronged approach. Sources of recruitment included: the Australian Electoral Commission, Medicare Australia databases, media campaigns through community newspapers and local radio, approaching directors of residential aged care facilities to pass information to potential participants or family members, monitoring hospital and outpatient aged care service contacts, attending meetings of senior citizens' organizations, and leaving information about the study in private physicians' surgeries in the area. Participants were also recruited from the 45 & Up Study and the Sydney Memory and Ageing Study.
- Participants from Existing Studies
-
- 45 & Up Study
- Sydney Memory and Ageing Study
Number of Participants
- Number of Participants
- 345
- Number of Participants with Biological Samples
- 224
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
SCS - Baseline
|
The baseline assessment comprised three separate home visits. Data gathered during the first visit included; demographics, lifetime medical history, current medications, fall history, ... |
2009-01 | 2016-12 |
| 1 |
SCS - 6 months follow-up
|
Brief follow-up assessments were conducted 6, 12 and 18 months after each participant’s baseline assessment. They included a cognitive screen, interval medical history, interval fall ... |
2009-07 | 2017-06 |
| 2 |
SCS - 12 months follow-up
|
Brief follow-up assessments were conducted 6, 12 and 18 months after each participant’s baseline assessment. They included a cognitive screen, interval medical history, interval fall ... |
2010-01 | 2017-12 |
| 3 |
SCS - 18 months follow-up
|
Brief follow-up assessments were conducted 6, 12 and 18 months after each participant’s baseline assessment. They included a cognitive screen, interval medical history, interval fall ... |
2010-07 | 2018-06 |
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
- Cognitive functioning
- Personality
- Psychological distress and emotions
- Other psychological measures and assessments
- Perception of health
- Quality of life
- Life course development
- Functional limitations
- Other perception of health, quality of life and functional limitation-related information
Socio-demographic and economic characteristics
Lifestyle and behaviours
Perception of health, quality of life, development and functional limitations
Diseases
Symptoms and signs
Medication and supplements
Non-pharmacological interventions
Health and community care services utilization
Death
Physical measures and assessments
Laboratory measures
Cognition, personality and psychological measures and assessments
Preschool, school and work life
Social environment and relationships
Administrative information
Cognitive functioning
Psychological distress and emotions
Quality of life
Functional limitations