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Seroprevalence of SARS-CoV-2 among African Canadians: Clinical and Epidemiological Correlates
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Seroprevalence of SARS-CoV-2 among African Canadians: Clinical and Epidemiological Correlates

Networks -
Datasets -
Variables -
Start Year
2020
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Investigators Contacts
  • Dr. Upton Allen
    The Hospital for Sick Children
  • Dr. Upton Allen
    The Hospital for Sick Children

Design

Study design
Cross-sectional
Follow Up
After baseline, participants who had a negative result for antibodies will have a chance for a re-test at 4-6 months following baseline visit. Participants who had a positive test for antibodies, will be followed-up at 6, 12, 18, and 24 months.

Recruitment

Recruitment Target
  • Individuals

Number of Participants

Number of Participants
3,000
Number of Participants with Biological Samples
3,000
Supplementary Information
The study includes 2000 adults and children from African Canadian communities within Ontario along with 1000 non-African Canadians. Only 300 individuals less than 19 years old will be included.

Access

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other
Yes
No
Not applicable
Don't know

Timeline

Populations

Selection Criteria
Minimum age
2
Newborns
Twins
Countries
  • Canada
Territory
Ethnic Origin
  • African Canadian
Health Status
  • Participants who are COVID-19 symptom-free at the time of enrollment are included.
    Participants who present symptomatic respiratory tract infection or other symptoms consistent with COVID-19 are excluded.
Supplementary Information about selection criteria
300 participants are less than 19 years old.

Recruitment

Sources of recruitment
  • General population
  • Specific population
General Population
  • Volunteer enrolment
Specific Population
  • Clinic patients
  • Other specific population : African Canadians
Supplementary Information
The majority of subjects are enrolled from the community. Some individuals are enrolled through hospitals. The 4 main models of enrollment based on the venues where subjects are enrolled are: * Model 1: hospitals * Model 2: community centre/church hall * Model 3: community health clinic * model 4: remote In model 1 (hospitals), the patient’s primary care team introduces the study. If the participant is interested in participating or obtaining more information, the research team would become engaged. Model 2 and Model 3 provide community venues where the study team enrolls participants and performs the study visit(s).

Number of Participants

Number of Participants
2,000
Number of Participants with Biological Samples
2,000
Data Collection Events
# Name Description Start End
0 seroMARK - African Canadians - Baseline Information about socio-demographic and medical conditions was collected. Blood samples were collected. 2020-12 2021-03
1 seroMARK - African Canadians - 4-6 month follow-up Blood samples were collected from COVID-19 negative participants. 2021-04 2021-09
2 seroMARK - African Canadians - 6 month follow-up Blood samples were collected from COVID-19 positive participants. 2021-06 2021-09
3 seroMARK - African Canadians - 12 month follow-up Blood samples were collected from COVID-19 positive participants. 2021-12 2022-03
4 seroMARK - African Canadians - 18 month follow-up Blood samples were collected from COVID-19 positive participants. 2022-06 2022-09
5 seroMARK - African Canadians - 24 month follow-up Blood samples were collected from COVID-19 positive participants. 2022-12 2023-03
Selection Criteria
Minimum age
2
Newborns
Twins
Countries
  • Canada
Territory
Ethnic Origin
Health Status
  • Participants who are COVID-19 symptom-free at the time of enrollment are included.
    Participants who present symptomatic respiratory tract infection or other symptoms consistent with COVID-19 are excluded.
Supplementary Information about selection criteria
300 participants are less than 19 years of age.

Recruitment

Sources of recruitment
  • General population
General Population
  • Selected sample
Supplementary Information
The majority of subjects are enrolled from the community. Some individuals are enrolled through hospitals. In this regard, 4 main models of enrollment based on the venues where subjects are enrolled are; * Model 1: hospitals * Model 2: community centre/church hall * Model 3: community health clinic * Model 4: remote. In model 1 (hospitals), the patient’s primary care team introduces the study. If the participant is interested in participating or obtaining more information, the research team would become engaged. Model 2 and Model 3 provide community venues where the study team enrolls participants and performs the study visit(s).

Number of Participants

Number of Participants
1,000
Number of Participants with Biological Samples
1,000
Data Collection Events
# Name Description Start End
0 seroMARK - Non-African Canadians - Baseline Information about sociodemographic and chronic medical conditions was collected. Blood samples were collected. 2020-12 2021-03
1 seroMARK - Non-African Canadians - 4-6 month follow-up Blood samples were collected from COVID-19 negative participants. 2021-04 2021-09
2 seroMARK - Non-African Canadians - 6 month follow-up Blood samples were collected from COVID-19 positive participants. 2021-06 2021-09
3 seroMARK - Non-African Canadians - 12 month follow-up Blood samples were collected from COVID-19 positive participants. 2021-12 2022-03
4 seroMARK - Non-African Canadians - 18 month follow-up Blood samples were collected from COVID-19 positive participants. 2022-06 2022-09
5 seroMARK - Non-African Canadians - 24 month follow-up Blood samples were collected from COVID-19 positive participants. 2022-12 2023-03

Classifications

Socio-demographic and economic characteristics
Lifestyle and behaviours
Birth, pregnancy and reproductive health history
Perception of health, quality of life, development and functional limitations
Diseases
Symptoms and signs
Medication and supplements
Non-pharmacological interventions
Health and community care services utilization
Death
Physical measures and assessments
Laboratory measures
Cognition, personality and psychological measures and assessments
Life events, life plans, beliefs and values
Preschool, school and work life
Social environment and relationships
Physical environment
Administrative information

Socio-demographic and economic characteristics

Age/birthdate
Sex/gender
Family and household structure
Education
Residence
Birthplace
Ethnicity, race and religion
Labour force and retirement
Income, possessions, and benefits
Other socio-demographic and economic characteristics

Lifestyle and behaviours

Transportation

Diseases

Certain infectious and parasitic diseases (A00-B99)
Neoplasms (C00-D48)
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Endocrine, nutritional and metabolic diseases (E00-E90)
Diseases of the nervous system (G00-G99)
Diseases of the circulatory system (I00-I99)
Diseases of the respiratory system (J00-J99)
Diseases of the genitourinary system (N00-N99)
Diseases without precise specification or falling into multiple categories

Medication and supplements

Medication and supplement intake

Non-pharmacological interventions

Laboratory diagnosis interventions
Other and unspecified non-pharmacological interventions

Health and community care services utilization

Visits to health professionals
Hospitalizations

Physical measures and assessments

Anthropometry

Laboratory measures

Virology

Social environment and relationships

Social participation

Physical environment

Housing characteristics

Administrative information

Identifiers
Date and time-related information
Physical and cognitive measure and biosample-related information