Swiss Ageing Citizen Reference
Networks
-
Datasets
-
Variables
-
The Swiss Ageing Citizen Reference (SACR) is a driver project from the Swiss Personalized Health Network that aims:
* To harmonize and apply data and biomaterial from existing Swiss citizen cohorts to build the well-embedded public health pillar of personalized health in Switzerland.
* To grant personalized health researchers responsible access to prospectively obtained information on health and health risks, to geocoded residential and work address history, and to archived biomaterial for testing the clinical and public health utility of candidate biomarkers and exposome features in predicting aging-related intermediate biomarkers (DNA methylation); MRI derived brain features), and subsequently aging-related (multi-) morbidities.
- Start Year
- 2020
- End Year
- 2023
- Supplementary Information
-
This study puts together three population-based cohorts:
* SAPALDIA
https://www.swisstph.ch/en/topics/non-communicable-diseases/human-biomonitoring/sapaldia/
* CoLaus|PsyCoLaus
http://www.colaus-psycolaus.ch/professionals/colaus/
http://www.colaus-psycolaus.ch/professionals/psycolaus/
* SKIPOGH
http://www.unisante.ch/fr/formation-recherche/recherche/projets-etudes/swiss-kidney-project-genes-hypertension-skipogh
https://www.maelstrom-research.org/study/skipogh
Visit SACR
| Investigators | Contacts |
|---|---|
|
|
Design
- Study design
- Cohort
- Follow Up
- Data collection was conducted between 2020 and 2023.
- Supplementary Information
Marker Paper
Jeong A, Bochud M, Cattin P, et al. SPHN - The Swiss Aging Citizen Reference (SACR). Stud Health Technol Inform. 2020 Jun 16;270:1168-1169. doi: 10.3233/SHTI200347.
PUBMED 32570565
Recruitment
- Recruitment Target
-
- Individuals
Number of Participants
- Number of Participants
- 902
- Number of Participants with Biological Samples
- 891
- Supplementary Information
- * Individuals recruited from the SAPALDIA cohort: 415 participants * Individuals recruited from the PsyCoLaus|CoLaus cohort: 360 participants * Individuals recruited from the SKIPOGH cohort: 127 participants
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
Access: https://www.swisstph.ch/en/projects/sacr
|
Timeline
SACR population
The population is composed of participants who were recruited within three existing population-based cohorts (SAPALDIA, CoLaus/PsyCoLaus, and SKIPOGH). The three original cohorts were composed of individuals from the general population in Switzerland living in Basel, Geneva, Lugano, Payerne, Wald, Aarau, Montana, and Davos for the SAPALDIA cohort; living in the City of Lausanne for the CoLaus/PsyCoLaus cohort; and living in Lausanne, Geneva, and Bern for the SKIPOGH cohort.
Selection Criteria
- Minimum age
-
18
- Maximum age
-
90
- Newborns
- Twins
- Countries
-
- Switzerland
- Territory
- Lausanne, Basel, Aarau, Davos, Payerne, Montana, Wald, Lugano, Geneva, Bern
- Ethnic Origin
-
- Health Status
-
- Other Criteria
Recruitment
- Sources of recruitment
-
- Participants from existing studies
- Participants from Existing Studies
-
- PsyCoLaus|CoLaus, SAPALDIA, SKIPOGH
Number of Participants
- Number of Participants
- 902
- Number of Participants with Biological Samples
- 891
- Supplementary Information about selection criteria
Data Collection Event
The following information is collected from harmonized data from 1991 to 2023 from pre-MRI cohort data:
* Address history, archived biomaterial-related information, socio-demographics (nutrition, exercise, alcohol consumption), lifestyle (behavours, exercise, alcohol consumption), medications, and aging parameters.
* Implicit memory function was assessed using a combined remember/know (PMID: 3210971) and pattern-separation (PMID: 23313292).
* Physical measures such as waist, hip and neck circumferences, height, weight, blood pressure, resting heart rate and peak handgrip measures.
* Blood samples data.
Raw voxel-based data into segmented data are measured per anatomical region and modality is collected through brain Magnetic Resonance Imaging (MRI).
DNA methylome and blood samples are collected.
- Start Date
-
2020
- End Date
-
2023
- Data sources
-
- Questionnaires
- Cognitive measures
- Physical measures
- Biosamples
- Other : Magnetic Resonance Imaging (MRI), DNA methylomne
- Data sources - Biosamples
-
- Blood
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
Socio-demographic and economic characteristics
Age/birthdate
Sex/gender
Education
Income, possessions, and benefits
Lifestyle and behaviours
Tobacco
Alcohol
Nutrition
Physical activity
Diseases
Endocrine, nutritional and metabolic diseases (E00-E90)
Mental and behavioural disorders (F00-F99)
Diseases of the circulatory system (I00-I99)
Diseases of the respiratory system (J00-J99)
Diseases of the genitourinary system (N00-N99)
Medication and supplements
Medication and supplement intake
Physical measures and assessments
Anthropometry
Circulation and respiration
Muscles, skeleton and mobility
Brain and nerves
Skin and subcutaneous tissue
Laboratory measures
Hematology
Biochemistry
Genomics
Administrative information
Identifiers
Date and time-related information
Physical and cognitive measure and biosample-related information