Individual Study / RS

Rotterdam Study

Rotterdam Study

Networks -
Datasets -
Variables -
Start Year
1989
Visit RS

Members

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Investigators Contacts
  • Prof. Albert Hofman
    Harvard University
  • Rotterdam Study Management team
    Erasmus MC University Medical Center Rotterdam

Design

Study design
Cohort
Follow Up
Following the initial phase (from 1989-1993), participants were followed up every 3 to 4 years.
Supplementary Information

Marker Paper

Ikram MA, Brusselle GGO, Murad SD, Van Duijn CM, Franco OH, Goedegebure A, Klaver CCW, Nijsten TEC, Peeters RP, Stricker BH, Tiemeier H, Uitterlinden G, Vernooij Meike W, Hofman A.The Rotterdam Study: 2018 update on objectives, design and main results. Eur J Epidemiol. 2017 Oct 24;32(9):807-850.

PUBMED 29064009

Recruitment

Recruitment Target
  • Individuals

Number of Participants

Number of Participants
18,926
Number of Participants with Biological Samples
10,000
Supplementary Information

Initially, there were 7983 participants. In 2000, 3011 participants (out of 4472 invitees) who had become 55 years of age or moved into the study district since the start of the study were added to the cohort. In 2006 a further extension of the cohort was initiated in which 3932 subjects were included, aged 45–54 years, out of 6057 invited, living in the Ommoord district. Since summer of 2016, another extension has started that includes all participants aged 40 years and over. The recruitment of this extension is expected to be completed in 2019 and yield around 4000 new participants.

Access

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other

Timeline

Rotterdam study population

Selection Criteria
Minimum age
40
Newborns
Twins
Countries
  • Netherlands
Territory
Ommoord district in the city of Rotterdam
Ethnic Origin
Health Status

Recruitment

Sources of recruitment
  • General population
General Population
  • Selected sample

Number of Participants

Number of Participants
18,926
Number of Participants with Biological Samples
10,000
Supplementary Information about selection criteria
RS-I-1: 7983 participants
RS-I-2: 6315 participants
RS-I-3: 4797 participants
RS-I-4: 3550 participants
RS-I-5: 2140 participants
RS-II-1: 3011 participants
RS-II-2: 2389 participants
RS-III-1: 3932 participants
RS-IV-1: 4000 participants
Data Collection Events
# Name Description Start End
0 RS-I-1

The participants were interviewed at home and then had an extensive set of examinations in a specially built research facility.

Information was obtained by questionnaire on current ...

1989-09 1993-09
1 RS-I-2

The participants were interviewed at home and then had an extensive set of examinations in a specially built research facility.

Information was obtained by questionnaire on current ...

1993-09 1995-12
2 RS-I-3

The participants were interviewed at home and then had an extensive set of examinations in a specially built research facility.

Information was obtained by questionnaire on current ...

1997-03 1999-12
3 RS-II-1

New participants were added to the cohort.

The participants were interviewed at home and then had an extensive set of examinations in a specially built research facility.

...
2000-02 2001-12
4 RS-I-4

The participants were interviewed at home and then had an extensive set of examinations in a specially built research facility.

Information was obtained by questionnaire on current ...

2002-01 2004-07
5 RS-II-2

The participants were interviewed at home and then had an extensive set of examinations in a specially built research facility.

Information was obtained by questionnaire on current ...

2004-07 2005-12
6 RS-III-1

New participants were added to the cohort.

The participants were interviewed at home and then had an extensive set of examinations in a specially built research facility.

...
2006-02 2008-12
7 RS-I-5

The participants were interviewed at home and then had an extensive set of examinations in a specially built research facility.

Information was obtained by questionnaire on current ...

2009-03 2011-01
8 RS-II-3

The participants were interviewed at home and then had an extensive set of examinations in a specially built research facility.

Information was obtained by questionnaire on current ...

2011-02 2012-02
9 RS-III-2

The participants were interviewed at home and then had an extensive set of examinations in a specially built research facility.

Information was obtained by questionnaire on current ...

2012-03 2014-06
10 RS-I-6

The participants were interviewed at home and then had an extensive set of examinations in a specially built research facility.

Information was obtained by questionnaire on current ...

2014-05 2015-07
11 RS-II-4

The participants were interviewed at home and then had an extensive set of examinations in a specially built research facility.

Information was obtained by questionnaire on current ...

2015-04 2016-02
12 RS-IV-1

New participants were added to the cohort.

The participants were interviewed at home and then had an extensive set of examinations in a specially built research facility.

...
2016-06 2020

Classifications

Socio-demographic and economic characteristics
Lifestyle and behaviours
Birth, pregnancy and reproductive health history
Perception of health, quality of life, development and functional limitations
Diseases
Symptoms and signs
Medication and supplements
Non-pharmacological interventions
Health and community care services utilization
Death
Physical measures and assessments
Laboratory measures
Cognition, personality and psychological measures and assessments
Life events, life plans, beliefs and values
Preschool, school and work life
Social environment and relationships
Physical environment
Administrative information

Socio-demographic and economic characteristics

Lifestyle and behaviours

Diseases

Health and community care services utilization

Death

Physical measures and assessments

Laboratory measures

Cognition, personality and psychological measures and assessments

Administrative information