POPCORN: COVID-19 Platform Prospective Cohort Study
Networks
-
Datasets
-
Variables
-
This overarching study aims to follow children across their entire healthcare trajectory to advance our understanding of children that present to the emergency department (ED) and/or are admitted to the hospital for severe acute SARS-CoV-2 infections, multisystem inflammatory syndrome (MIS-C), myocarditis, and pericarditis and detect signals of emerging syndromes in children.
The specific aims of this study are;
* To evaluate the short and long-term clinical outcomes and health consequences among children diagnosed with acute COVID-19 illness and their families, compared to SARS-CoV-2 negative controls and their families.
* To evaluate the predictors (or risk factors) for severe disease and poor outcomes (hospitalization, critical illness, and mortality), from COVID-19 by comparing characteristics of children with/without COVID-19 who do and do not experience severe outcomes.
* To compare the short- and long-term outcomes and health consequences among children with myocarditis, pericarditis and MIS-C occurring as a) adverse events following SARS-CoV-2 immunization (AEFIs) and b) as complications of SARS-CoV-2 infection and to assess consequences for their families.
* To examine equity considerations in COVID-19 acute disease, events following vaccination, and long-term outcomes by applying social and structural determinants of health lens including but not limited to analyses based on race/ethnicity/Indigenous identity, immigration status, gender, LGBTQIA2S+ identity, language, disabilities, and household income level.
* To collect biological samples from patients with confirmed MIS-C, myocarditis, and pericarditis following SARS-CoV-2 vaccination or infection and appropriate, matched controls for biobanking and later inclusion in national and international studies into the causes and risk factors of AEFIs and MIS-C (Translational sub-study). Additionally, samples will be collected from unmatched controls.
- Start Year
- 2023
- End Year
- 2024
Visit POPCORN-COVID-19
| Investigators | Contacts |
|---|---|
|
Design
- Study design
- Cohort
- Follow Up
- * All the participants are followed up at 1 week, 2 months, 6 months and 12 months after baseline. * The follow-up "date" varies depending on the date the patient became eligible for the study.
Recruitment
- Recruitment Target
-
- Individuals
Number of Participants
- Number of Participants
- 40,000
- Number of Participants with Biological Samples
- Supplementary Information
- Target / planned size: ≈ 40,000+ participants
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
Timeline
Populations
The population is composed of children under 18 years of age who tested positive for SARS-CoV-2 infection by reverse transcription-polymerase chain reaction (RT-PCR Test) or equivalent and presenting with acute COVID-19-like symptoms.
Selection Criteria
- Maximum age
-
17
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Ethnic Origin
-
- Health Status
-
- Paricipants are included in the the study if they; * Presented or admitted to a participating pediatric ED, inpatient ward, or Pediatric Intensive Care Unit. * Presented with one or more COVID-19 compatible symptoms (respiratory, febrile young infant <60 days, gastrointestinal, other). * If they tested for SARS-CoV-2 infection.
- Other Criteria
- Supplementary Information about selection criteria
- Participants may consent to the biobank as a biobank control.
Recruitment
- Sources of recruitment
-
- Specific population
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Paricipants are recruited across 16 academic pediatric institutions which are BC Children’s Hospital (Vancouver), Stollery Children’s Hospital (Edmonton), Alberta Children’s Hospital (Calgary), Jim Pattison Children’s Hospital (Saskatoon), The Children’s Hospital of Winnipeg (Winnipeg), McMaster Children’s Hospital (Hamilton), The Hospital for Sick Children (Toronto), Kingston Health Sciences Centre (Kingston), Children’s Hospital of Eastern Ontario (Ottawa), Children's Hospital London Health Sciences Centre (London), Montreal Children’s Hospital (Montreal), CHU Sainte-Justine (Montreal), CHU de Sherbrooke (Sherbrooke), CHU de Quebec l‘Université de Laval (Quebec City), Janeway Children’s Health and Rehabilitation Centre (St. John’s), and IWK Health Centre (Halifax).
Number of Participants
- Number of Participants
- 2,000
- Number of Participants with Biological Samples
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
POPCORN-COVID-19 - SARS-CoV-2 positive Case - Baseline
|
Information on demographics, height and weight, premature birth, SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine manufacturer, number of doses), ... | 2023-01 | 2024-03 |
| 1 |
POPCORN-COVID-19 - SARS-CoV-2 positive Case - First follow-up (0 to 9 days)
|
Information on patient status, quality of life (Pediatric Quality of Life Inventory) and disability (Functional Status Scale Survey) is collected. | 2023-01 | 2024-03 |
| 2 |
POPCORN-COVID-19 - SARS-CoV-2 positive Case - Second follow-up (2 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-03 | 2024-03 |
| 4 |
POPCORN-COVID-19 - SARS-CoV-2 positive Case - Third follow-up (6 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-07 | 2024-03 |
| 5 |
POPCORN-COVID-19 - SARS-CoV-2 positive Case - Fourth follow-up (12 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2024-01 | 2024-03 |
The population is composed of children under 18 years of age who tested positive for SARS-CoV-2 infection by reverse transcription-polymerase chain reaction (RT-PCR Test) or equivalent and did not present with acute COVID-19-like symptoms.
Selection Criteria
- Maximum age
-
17
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Ethnic Origin
-
- Health Status
-
- Paricipants are included in the the study if they; * Presented or admitted to a participating pediatric ED, inpatient ward, or Pediatric Intensive Care Unit. * If they tested for SARS-CoV-2 infection.
- Other Criteria
- Supplementary Information about selection criteria
- Participants were enrolled but not matched to controls.
Recruitment
- Sources of recruitment
-
- Specific population
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Paricipants are recruited across 16 academic pediatric institutions which are BC Children’s Hospital (Vancouver), Stollery Children’s Hospital (Edmonton), Alberta Children’s Hospital (Calgary), Jim Pattison Children’s Hospital (Saskatoon), The Children’s Hospital of Winnipeg (Winnipeg), McMaster Children’s Hospital (Hamilton), The Hospital for Sick Children (Toronto), Kingston Health Sciences Centre (Kingston), Children’s Hospital of Eastern Ontario (Ottawa), Children's Hospital London Health Sciences Centre (London), Montreal Children’s Hospital (Montreal), CHU Sainte-Justine (Montreal), CHU de Sherbrooke (Sherbrooke), CHU de Quebec l‘Université de Laval (Quebec City), Janeway Children’s Health and Rehabilitation Centre (St. John’s), and IWK Health Centre (Halifax).
Number of Participants
- Number of Participants
- No Limit
- Number of Participants with Biological Samples
- No Limit
- Supplementary Information about selection criteria
- As of September 2023, the total number of participants is 9. There is no limit to the number of participants that can be recruited for this population.
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
POPCORN-COVID-19 - SARS-CoV-2 positive incidental Case - Baseline
|
Information on demographics, height and weight, premature birth, SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine manufacturer, number of doses), ... | 2023-01 | 2024-03 |
| 1 |
POPCORN-COVID-19 - SARS-CoV-2 positive incidental Case - First follow-up (0 to 9 days)
|
Information on patient status, quality of life (Pediatric Quality of Life Inventory) and disability (Functional Status Scale Survey) is collected. | 2023-01 | 2024-03 |
| 2 |
POPCORN-COVID-19 - SARS-CoV-2 positive incidental Case - Second follow-up (2 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-03 | 2024-03 |
| 3 |
POPCORN-COVID-19 - SARS-CoV-2 positive incidental Case - Third follow-up (6 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-07 | 2024-03 |
| 4 |
POPCORN-COVID-19 - SARS-CoV-2 positive incidental Case - Fourth follow-up (12 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2024-01 | 2024-03 |
The population is composed of children under 18 years of age who are pediatric ED patients or inpatient ward units with acute non-febrile or mild febrile illness, accidental injury, or outpatients requiring bloodwork for other reasons and who tested negative for SARS-CoV-2 infection by reverse transcription-polymerase chain reaction (RT-PCR) or equivalent and presenting with acute COVID-19-like symptoms.
Selection Criteria
- Maximum age
-
17
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Ethnic Origin
-
- Health Status
-
- Participants are included if they tested for SARS-CoV-2 infection. Presented symptoms related other respiratory infectious syndromes (e.g., respiratory syncytial virus, influenza), febrile young infant < 60 days, gastrointestinal symptoms – including hepatitis, and others (e.g., neurological)).
- Supplementary Information about selection criteria
- Participants consented to the biobank only as a biobank control.
Recruitment
- Sources of recruitment
-
- Specific population
- Specific Population
-
- Clinic patients
- Supplementary Information
-
* Paricipants are recruited across 16 academic pediatric institutions which are BC Children’s Hospital (Vancouver), Stollery Children’s Hospital (Edmonton), Alberta Children’s Hospital (Calgary), Jim Pattison Children’s Hospital (Saskatoon), The Children’s Hospital of Winnipeg (Winnipeg), McMaster Children’s Hospital (Hamilton), The Hospital for Sick Children (Toronto), Kingston Health Sciences Centre (Kingston), Children’s Hospital of Eastern Ontario (Ottawa), Children's Hospital London Health Sciences Centre (London), Montreal Children’s Hospital (Montreal), CHU Sainte-Justine (Montreal), CHU de Sherbrooke (Sherbrooke), CHU de Quebec l‘Université de Laval (Quebec City), Janeway Children’s Health and Rehabilitation Centre (St. John’s), and IWK Health Centre (Halifax).
Number of Participants
- Number of Participants
- 4,000
- Number of Participants with Biological Samples
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
POPCORN-COVID-19 - SARS-CoV-2 negative Control - Baseline
|
Information on demographics, height and weight, premature birth, SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine manufacturer, number of doses), ... | 2023-01 | 2024-03 |
| 1 |
POPCORN-COVID-19 - SARS-CoV-2 negative Control - First follow-up (0 to 9 days)
|
Information on patient status, quality of life (Pediatric Quality of Life Inventory) and disability (Functional Status Scale Survey) is collected. | 2023-01 | 2024-03 |
| 2 |
POPCORN-COVID-19 - SARS-CoV-2 negative Control - Second follow-up (2 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-03 | 2024-03 |
| 4 |
POPCORN-COVID-19 - SARS-CoV-2 negative Control - Third follow-up (6 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-07 | 2024-03 |
| 5 |
POPCORN-COVID-19 - SARS-CoV-2 negative Control - Fourth follow-up (12 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2024-01 | 2024-03 |
The population is composed of children under 18 years of age with clinical criteria consistent with myocarditis or pericarditis presenting to the ED or participating pediatric institution to be assessed by a physician.
Selection Criteria
- Maximum age
-
17
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Ethnic Origin
-
- Health Status
-
- Paricipants are included in the the study if they; * Presented or admitted to a participating pediatric ED, inpatient ward, or Pediatric Intensive Care Unit. * Diagnostic bloodwork for Myocarditis and Pericarditis was ordered or expected to be ordered based on assessment by triage or admitting teams. * Activation of a myocarditis or pericarditis clinical pathway * Another known cause for the child’s presentation determined prior to blood draw
- Other Criteria
- Supplementary Information about selection criteria
- Participants may consent to the biobank as a biobank case.
Recruitment
- Sources of recruitment
-
- Specific population
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Paricipants are recruited across 16 academic pediatric institutions which are BC Children’s Hospital (Vancouver), Stollery Children’s Hospital (Edmonton), Alberta Children’s Hospital (Calgary), Jim Pattison Children’s Hospital (Saskatoon), The Children’s Hospital of Winnipeg (Winnipeg), McMaster Children’s Hospital (Hamilton), The Hospital for Sick Children (Toronto), Kingston Health Sciences Centre (Kingston), Children’s Hospital of Eastern Ontario (Ottawa), Children's Hospital London Health Sciences Centre (London), Montreal Children’s Hospital (Montreal), CHU Sainte-Justine (Montreal), CHU de Sherbrooke (Sherbrooke), CHU de Quebec l‘Université de Laval (Quebec City), Janeway Children’s Health and Rehabilitation Centre (St. John’s), and IWK Health Centre (Halifax).
Number of Participants
- Number of Participants
- 100
- Number of Participants with Biological Samples
- 50
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
POPCORN-COVID-19 - Myocarditis and Pericarditis Case - Baseline
|
Information on demographics, height and weight, premature birth, SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine manufacturer, number of doses), ... | 2023-01 | 2024-03 |
| 1 |
POPCORN-COVID-19 - Myocarditis and Pericarditis Case - First follow-up (0 to 9 days)
|
Information on patient status, quality of life (Pediatric Quality of Life Inventory) and disability (Functional Status Scale Survey) is collected. | 2023-01 | 2024-03 |
| 2 |
POPCORN-COVID-19 - Myocarditis and Pericarditis Case - Second follow-up (2 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-03 | 2024-03 |
| 4 |
POPCORN-COVID-19 - Myocarditis and Pericarditis Case - Third follow-up (6 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-07 | 2024-03 |
| 5 |
POPCORN-COVID-19 - Myocarditis and Pericarditis Case - Fourth follow-up (12 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2024-01 | 2024-03 |
The population is composed of children under 18 years of age who are pediatric ED patients or inpatient ward units with acute non-febrile or mild febrile illness, accidental injury, or outpatients requiring bloodwork for other reasons and who have a recent history of COVID-19 vaccination (past 30 days) or with clinical criteria consistent with myocarditis or pericarditis cases but, upon assessment by a physician, did not receive the diagnosis.
Selection Criteria
- Maximum age
-
17
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Ethnic Origin
-
- Health Status
-
- Paricipants are included in the the study if they; * Presented or admitted to a participating pediatric ED, inpatient ward, or Pediatric Intensive Care Unit. * Diagnostic bloodwork for Myocarditis and pericarditis was ordered or expected to be ordered based on assessment by triage or admitting teams however, an alternate diagnosis was determined, or investigations were normal.
- Other Criteria
- Supplementary Information about selection criteria
- Participants consented to the biobank only as a biobank control.
Recruitment
- Sources of recruitment
-
- Specific population
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Paricipants are recruited across 16 academic pediatric institutions which are BC Children’s Hospital (Vancouver), Stollery Children’s Hospital (Edmonton), Alberta Children’s Hospital (Calgary), Jim Pattison Children’s Hospital (Saskatoon), The Children’s Hospital of Winnipeg (Winnipeg), McMaster Children’s Hospital (Hamilton), The Hospital for Sick Children (Toronto), Kingston Health Sciences Centre (Kingston), Children’s Hospital of Eastern Ontario (Ottawa), Children's Hospital London Health Sciences Centre (London), Montreal Children’s Hospital (Montreal), CHU Sainte-Justine (Montreal), CHU de Sherbrooke (Sherbrooke), CHU de Quebec l‘Université de Laval (Quebec City), Janeway Children’s Health and Rehabilitation Centre (St. John’s), and IWK Health Centre (Halifax).
Number of Participants
- Number of Participants
- 100
- Number of Participants with Biological Samples
- 200
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
POPCORN-COVID-19 - Myocarditis and Pericarditis Control - Baseline
|
Information on demographics, height and weight, premature birth, SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine manufacturer, number of doses), ... | 2023-01 | 2024-03 |
| 1 |
POPCORN-COVID-19 - Myocarditis and Pericarditis Control - First follow-up (0 to 9 days)
|
Information on patient status, quality of life (Pediatric Quality of Life Inventory) and disability (Functional Status Scale Survey) is collected. | 2023-01 | 2024-03 |
| 2 |
POPCORN-COVID-19 - Myocarditis and Pericarditis Control - Second follow-up (2 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-03 | 2024-03 |
| 4 |
POPCORN-COVID-19 - Myocarditis and Pericarditis Control - Third follow-up (6 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-07 | 2024-03 |
| 5 |
POPCORN-COVID-19 - Myocarditis and Pericarditis Control - Fourth follow-up (12 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2024-01 | 2024-03 |
The population is composed of children under 18 years of age with clinical criteria consistent with MIS-C presenting to the ED or participating pediatric institution to be assessed by a physician.
Selection Criteria
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Ethnic Origin
-
- Health Status
-
- Paricipants are included in the the study if they; * Presented or admitted to a participating pediatric ED, inpatient ward, or PICU * Fever in last 24 hours * Activation of a MIS-C clinical pathway * Another known cause for the child’s presentation determined prior to blood draw * Diagnostic bloodwork for MIS-C was ordered or expected to be ordered based on assessment by triage or admitting teams
- Other Criteria
- Supplementary Information about selection criteria
- Participants may consent to the biobank as a biobank case.
Recruitment
- Sources of recruitment
-
- Specific population
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Paricipants are recruited across 16 academic pediatric institutions which are BC Children’s Hospital (Vancouver), Stollery Children’s Hospital (Edmonton), Alberta Children’s Hospital (Calgary), Jim Pattison Children’s Hospital (Saskatoon), The Children’s Hospital of Winnipeg (Winnipeg), McMaster Children’s Hospital (Hamilton), The Hospital for Sick Children (Toronto), Kingston Health Sciences Centre (Kingston), Children’s Hospital of Eastern Ontario (Ottawa), Children's Hospital London Health Sciences Centre (London), Montreal Children’s Hospital (Montreal), CHU Sainte-Justine (Montreal), CHU de Sherbrooke (Sherbrooke), CHU de Quebec l‘Université de Laval (Quebec City), Janeway Children’s Health and Rehabilitation Centre (St. John’s), and IWK Health Centre (Halifax).
Number of Participants
- Number of Participants
- 300
- Number of Participants with Biological Samples
- 150
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
POPCORN-COVID-19 - MIS-C Case - Baseline
|
Information on demographics, height and weight, premature birth, SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine manufacturer, number of doses), ... | 2023-01 | 2024-03 |
| 1 |
POPCORN-COVID-19 - MIS-C Case - First follow-up (0 to 9 days)
|
Information on patient status, quality of life (Pediatric Quality of Life Inventory) and disability (Functional Status Scale Survey) is collected. | 2023-01 | 2024-03 |
| 2 |
POPCORN-COVID-19 - MIS-C Case - Second follow-up (2 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-03 | 2024-03 |
| 4 |
POPCORN-COVID-19 - MIS-C Case - Third follow-up (6 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-07 | 2024-03 |
| 5 |
POPCORN-COVID-19 - MIS-C Case - Fourth follow-up (12 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2024-01 | 2024-03 |
The population is composed of children under 18 years of age who are pediatric ED patients or inpatient ward units with acute non-febrile or mild febrile illness, accidental injury, or outpatients requiring bloodwork for other reasons and who have a recent history of COVID-19 vaccination (past 30 days) or with clinical criteria consistent with MIS-C cases but, upon assessment by a physician, did not receive the diagnosis.
Selection Criteria
- Maximum age
-
17
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Ethnic Origin
-
- Health Status
-
- Paricipants are included in the the study if they; * Presented or admitted to a participating pediatric ED, inpatient ward, or PICU * Fever in last 24 hours * Diagnostic bloodwork for MIS-C was ordered or expected to be ordered based on assessment by triage or admitting teams however, an alternate diagnosis was determined, or investigations were normal. * Another known cause for the child’s presentation determined prior to blood draw
- Other Criteria
- Supplementary Information about selection criteria
- Participants consented to the biobank only as a biobank control.
Recruitment
- Sources of recruitment
-
- Specific population
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Paricipants are recruited across 16 academic pediatric institutions which are BC Children’s Hospital (Vancouver), Stollery Children’s Hospital (Edmonton), Alberta Children’s Hospital (Calgary), Jim Pattison Children’s Hospital (Saskatoon), The Children’s Hospital of Winnipeg (Winnipeg), McMaster Children’s Hospital (Hamilton), The Hospital for Sick Children (Toronto), Kingston Health Sciences Centre (Kingston), Children’s Hospital of Eastern Ontario (Ottawa), Children's Hospital London Health Sciences Centre (London), Montreal Children’s Hospital (Montreal), CHU Sainte-Justine (Montreal), CHU de Sherbrooke (Sherbrooke), CHU de Quebec l‘Université de Laval (Quebec City), Janeway Children’s Health and Rehabilitation Centre (St. John’s), and IWK Health Centre (Halifax).
Number of Participants
- Number of Participants
- 300
- Number of Participants with Biological Samples
- 200
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
POPCORN-COVID-19 - MIS-C Control - Baseline
|
Information on demographics, height and weight, premature birth, SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine manufacturer, number of doses), ... | 2023-01 | 2024-03 |
| 1 |
POPCORN-COVID-19 - MIS-C Control - First follow-up (0 to 9 days)
|
Information on patient status, quality of life (Pediatric Quality of Life Inventory) and disability (Functional Status Scale Survey) is collected. | 2023-01 | 2024-03 |
| 2 |
POPCORN-COVID-19 - MIS-C Control - Second follow-up (2 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-03 | 2024-03 |
| 4 |
POPCORN-COVID-19 - MIS-C Control - Third follow-up (6 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2023-07 | 2024-03 |
| 5 |
POPCORN-COVID-19 - MIS-C Control - Fourth follow-up (12 months)
|
Information on patient status, healthcare encounters (visits and stays at the hospital/ED), SARS-CoV-2 infections (symptoms, history, testing, exposure) and vaccinations (dates, vaccine ... | 2024-01 | 2024-03 |
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
- Cognitive functioning
- Personality
- Psychological distress and emotions
- Other psychological measures and assessments
- Perception of health
- Quality of life
- Life course development
- Functional limitations
- Other perception of health, quality of life and functional limitation-related information
Socio-demographic and economic characteristics
Age/birthdate
Sex/gender
Marital/partner status
Family and household structure
Education
Residence
Birthplace
Citizenship and immigrant status
Ethnicity, race and religion
Language
Labour force and retirement
Income, possessions, and benefits
Lifestyle and behaviours
Tobacco
Physical activity
Other and unspecified lifestyle information
Perception of health, quality of life, development and functional limitations
Quality of life
Life course development
Functional limitations
Diseases
Certain infectious and parasitic diseases (A00-B99)
Neoplasms (C00-D48)
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Endocrine, nutritional and metabolic diseases (E00-E90)
Diseases of the nervous system (G00-G99)
Diseases of the circulatory system (I00-I99)
Diseases of the respiratory system (J00-J99)
Diseases of the digestive system (K00-K93)
Diseases of the skin and subcutaneous tissue (L00-L99)
Diseases of the musculoskeletal system and connective tissue (M00-M99)
Diseases of the genitourinary system (N00-N99)
Certain conditions originating in the perinatal period (P00-P96)
Injury, poisoning and certain other consequences of external causes (S00-T98)
Diseases without precise specification or falling into multiple categories
Symptoms and signs
Symptoms and signs involving the circulatory and respiratory systems (R00-R09)
Symptoms and signs involving cognition, perception, emotional state and behaviour (R40-R46)
General symptoms and signs (R50-R69)
Symptoms related to multiple categories
Medication and supplements
Medication and supplement intake
Posology and protocol of administration
Non-pharmacological interventions
Radiological interventions
Laboratory diagnosis interventions
Other and unspecified non-pharmacological interventions
Health and community care services utilization
Visits to health professionals
Hospitalizations
Death
Vital status
Cause of death
Physical measures and assessments
Anthropometry
Circulation and respiration
Other physical measures and assessments
Laboratory measures
Hematology
Biochemistry
Microbiology
Virology
Immunology
Histology
Other laboratory measures
Cognition, personality and psychological measures and assessments
Psychological distress and emotions
Physical environment
Chemical exposure
Biological exposure
Administrative information
Identifiers
Date and time-related information
Questionnaire and interview-related information
Physical and cognitive measure and biosample-related information
Data and sample collection center-related information
Other administrative information
Psychological distress and emotions
Revised Children's Anxiety and Depression Scale
Quality of life
Pediatric Quality of Life Inventory
Functional limitations
Functional Status Scale