Prospective investigation of Obesity, Energy and Metabolism
Networks
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Datasets
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Variables
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The Prospective investigation of Obesity, Energy and Metabolism is aiming to study pathophysiological links between obesity and vascular dysfunction and future cardiovascular disorders.
- Start Year
- 2010
- End Year
- 2016
- Supplementary Information
Visit POEM
| Investigators | Contacts |
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Design
- Study design
- Cohort
Marker Paper
Lind L. Relationships between three different tests to evaluate endothelium-dependent vasodilation and cardiovascular risk in a middle-aged sample. J Hypertens. 2013;31(8):1570-1574.
PUBMED 23625114
Recruitment
- Recruitment Target
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- Individuals
Number of Participants
- Number of Participants
- 502
- Number of Participants with Biological Samples
- 502
- Supplementary Information
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
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Timeline
POEM population
The population is composed of inhabitants of Uppsala, Sweden aged 50.
Selection Criteria
- Minimum age
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50
- Maximum age
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50
- Newborns
- Twins
- Countries
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- Sweden
- Territory
- Uppsala
- Ethnic Origin
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- Health Status
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- Other Criteria
- Participants needed to have a Swedish identification number.
- Supplementary Information about selection criteria
- To obtain a sufficient power, the study will also include a certain number of obese subjects.
Recruitment
- Sources of recruitment
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- General population
- General Population
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- Selected sample
- Supplementary Information
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The individuals were invited in a random order from the register of inhabitants in the city 1 month following their 50th birthday.
Number of Participants
- Number of Participants
- 502
- Number of Participants with Biological Samples
- 502
- Supplementary Information about selection criteria
Data Collection Event
Self-reported history of diseases and medication, as well as lifestyle behaviors (exercise, smoking, alcohol intake), education, social network, number of teeth etc. were collected through questionnaires. Food intake was also assessed using the Food Frequency Questionnaire (FFQ).
A number of tests evaluating endothelial function, arterial compliance, atherosclerosis, myocardial geometry and function and heart rate variability were performed together with a 24h ambulatory blood pressure recording. Regarding energy and metabolism, basal energy expenditure was measured by indirect calorimetry; maximum rate of oxygen consumption (maximal VO2) was evaluated by a maximal bicycle test; physical activity was evaluated by an accelerometer. Anthropometrical measurements were taken by bioimpedance, abdominal fat by MRI scan; and bone mineralization, fat mass and lean mass by DXA - scanning. Sleep apnea was diagnosed from an overnight sleep registration using the Watch-Path device.
A number of serum/plasma samples were collected and an oral glucose tolerance test (OGTT) was performed. Urine samples were collected.
- Start Date
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2010-10
- End Date
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2016-10
- Data sources
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- Questionnaires
- Physical measures
- Biosamples
- Data sources - Biosamples
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- Blood
- Urine
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
Socio-demographic and economic characteristics
Age/birthdate
Sex/gender
Education
Birthplace
Lifestyle and behaviours
Tobacco
Physical activity
Sleep
Birth, pregnancy and reproductive health history
Puberty, menstruation, menopause and andropause
Pregnancy, delivery and birth
Fertility and sexual health
Diseases
Endocrine, nutritional and metabolic diseases (E00-E90)
Diseases of the circulatory system (I00-I99)
Diseases of the respiratory system (J00-J99)
Pregnancy, childbirth and the puerperium (O00-O9A)
Medication and supplements
Medication and supplement intake
Non-pharmacological interventions
Surgical interventions
Other and unspecified non-pharmacological interventions
Physical measures and assessments
Physical characteristics
Anthropometry
Circulation and respiration
Skin and subcutaneous tissue
Digestion
Other physical measures and assessments
Laboratory measures
Hematology
Biochemistry
Administrative information
Identifiers
Date and time-related information