Prospective Investigation of the Vasculature in Uppsala Seniors
Networks
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Datasets
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Variables
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The primary aim of the PIVUS study was to study the pathogenesis of atherosclerosis and its related diseases by investigating the predictive power of different measurements of endothelial function and arterial compliance regarding future cardiovascular events. As secondary aims, the study also included measurements of cardiac function and structure by ultrasound and MRI, evaluation of atherosclerosis by ultrasound and MRI, 7-day food intake recordings, detailed ECG analysis, cardiovascular autonomic function, body composition by DXA, DNA analysis and lung function, cognitive function tests, as well as a number of biochemical markers.
- Start Year
- 2001
- End Year
- 2014
Visit PIVUS
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Design
- Study design
- Cohort
- Follow Up
- Participants were followed-up twice, at 5-year intervals.
- Supplementary Information
Marker Paper
Lind L, Fors N, Hall J, Marttala K, Stenborg A. A comparison of three different methods to evaluate endothelium-dependent vasodilation in the elderly: the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Arterioscler Thromb Vasc Biol. 2005;25(11):2368-2375.
PUBMED 16141402
Recruitment
- Recruitment Target
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- Individuals
Number of Participants
- Number of Participants
- 1,016
- Number of Participants with Biological Samples
- 1,016
- Supplementary Information
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
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Supplementary Information
http://www.medsci.uu.se/pivus/publications/
Timeline
PIVUS population
The population consisted of subjects aged 70 years, who were living in the community of Uppsala, Sweden, chosen from the register of community living and invited to participate in a randomized order.
Selection Criteria
- Minimum age
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70
- Maximum age
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70
- Newborns
- Twins
- Countries
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- Sweden
- Territory
- Uppsala
- Ethnic Origin
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- Health Status
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- Supplementary Information about selection criteria
Recruitment
- Sources of recruitment
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- General population
- General Population
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- Selected sample
- Supplementary Information
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All individuals aged 70 years living in the community of Uppsala, Sweden were eligible to participate. Participants were chosen randomly from the register of community living and received an invitation letter within 2 months of their 70th birthday.
Number of Participants
- Number of Participants
- 1,016
- Number of Participants with Biological Samples
- 1,016
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
PIVUS – 70 years
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Through a questionnaire, information was obtained about history of diseases and medication, as well as several other items regarding lifestyle, such as exercise, smoking, alcohol intake, education ... | 2001-04 | 2004-06 |
| 1 |
PIVUS – 75 years
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The major measurements performed at age 70 were repeated at age 75. Through a questionnaire, information was obtained about history of diseases and medication, as well as several other items ... | 2006-03 | 2009-07 |
| 2 |
PIVUS – 80 years
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Through a questionnaire, information was obtained about history of diseases and medication, as well as several other items regarding lifestyle, such as exercise, smoking, alcohol intake, education ... | 2011-04 | 2014-06 |
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
- Cognitive functioning
- Personality
- Psychological distress and emotions
- Other psychological measures and assessments
- Tobacco
- Alcohol
- Drugs
- Nutrition
- Breastfeeding
- Physical activity
- Sleep
- Sexual behaviours and orientation
- Technological devices
- Misbehaviour and criminality
- Other and unspecified lifestyle information
Socio-demographic and economic characteristics
Age/birthdate
Sex/gender
Education
Lifestyle and behaviours
Tobacco
Nutrition
Physical activity
Sleep
Birth, pregnancy and reproductive health history
Puberty, menstruation, menopause and andropause
Pregnancy, delivery and birth
Diseases
Endocrine, nutritional and metabolic diseases (E00-E90)
Diseases of the circulatory system (I00-I99)
Diseases of the respiratory system (J00-J99)
Symptoms and signs
Symptoms and signs involving the circulatory and respiratory systems (R00-R09)
Medication and supplements
Medication and supplement intake
Non-pharmacological interventions
Surgical interventions
Other and unspecified non-pharmacological interventions
Health and community care services utilization
Hospitalizations
Death
Vital status
Cause of death
Physical measures and assessments
Physical characteristics
Anthropometry
Circulation and respiration
Muscles, skeleton and mobility
Laboratory measures
Hematology
Biochemistry
Immunology
Cognition, personality and psychological measures and assessments
Cognitive functioning
Preschool, school and work life
Work life
Social environment and relationships
Social network
Administrative information
Identifiers
Date and time-related information
Physical and cognitive measure and biosample-related information
Other administrative information
Cognitive functioning
Mini-Mental State Examination
Nutrition
7-Day Dietary Record