Lausanne Cohort 65+
Networks
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Datasets
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Variables
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The objectives of this study are to:
* Contribute to the epidemiological and public health research on ageing with a particular focus on the determinants, manifestations and outcomes of frailty.
* Provide continuous health indicators to offer guidance on public health actions to the Public Health Department of the canton Vaud.
* Conduct geriatric research based on a broad range of measures that cover both self-reported and performance-based assessments.
- Start Year
- 2004
Visit Lc65
| Investigators | Contacts |
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Design
- Study design
- Cohort
- Follow Up
- After baseline, participants were followed-up with questionnaires each year and at an in-person interview and an examination every third year.
Marker Paper
Henchoz Y, Blanco JM, Fustinoni S, Nanchen D, Bula C, Seematter-Bagnoud L, von Gunten A, Santos-Eggimann B. Cohort Profile: The Lausanne cohort 65+ (Lc65+). Int J Epidemiol. Online ahead of print.
PUBMED 34849932
Recruitment
- Recruitment Target
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- Individuals
Number of Participants
- Number of Participants
- 4,731
- Number of Participants with Biological Samples
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
Timeline
Populations
The population is composed of non-institutionalized males and females aged 65 to 70 in 2004 (birth year 1934 to 1938).
Selection Criteria
- Minimum age
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65
- Maximum age
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70
- Newborns
- Twins
- Countries
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- Switzerland
- Territory
- Lausanne
- Ethnic Origin
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- Health Status
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- Individuals unable to respond due to cognitive impairment were excluded.
- Other Criteria
- Institutionalized individuals were excluded.
Recruitment
- Sources of recruitment
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- General population
- General Population
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- Selected sample
- Supplementary Information
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The first stage of sampling and recruitment in the Lc65+ study took place in 2004. Participants were selected by simple random sampling of city residents comprising 3236 individuals born between 1934 and 1938 extracted by the Population Office in April 2003. In March 2004, all selected individuals received a support letter from the Surgeon General of the Canton of Vaud, followed one week later by a mailing including a presentation of the study, an initial self-administered questionnaire, and a stamped return envelope. Non-respondents received two follow-up mailshots with the same contents. The last mailing included an anonymous form for reporting refusals and corresponding reasons.
Number of Participants
- Number of Participants
- 1,564
- Number of Participants with Biological Samples
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
Lc65 - Sample 1 - Baseline
|
A self-completed questionnaire covered specific life course characteristics such as life history from childhood, through adulthood and until the time of completing the questionnaire (i.e. 65 to 70 ... | 2004 | 2005 |
| 2 |
Lc65 - Sample 1 - Follow-up 1
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2006 | 2006 |
| 3 |
Lc65 - Sample 1 - Follow-up 2
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2007 | 2007 |
| 4 |
Lc65 - Sample 1 - Follow-up 3
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2008 | 2008 |
| 5 |
Lc65 - Sample 1 - Follow-up 4
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2009 | 2009 |
| 6 |
Lc65 - Sample 1 - Follow-up 5
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2010 | 2010 |
| 7 |
Lc65 - Sample 1 - Follow-up 6
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2011 | 2011 |
| 8 |
Lc65 - Sample 1 - Follow-up 7
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2012 | 2012 |
| 9 |
Lc65 - Sample 1 - Follow-up 8
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2013 | 2013 |
| 10 |
Lc65 - Sample 1 - Follow-up 9
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2014 | 2014 |
| 11 |
Lc65 - Sample 1 - Follow-up 10
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2015 | 2015 |
| 12 |
Lc65 - Sample 1 - Follow-up 11
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2016 | 2016 |
| 13 |
Lc65 - Sample 1 - Follow-up 12
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2017 | 2017 |
| 14 |
Lc65 - Sample 1 - Follow-up 13
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2018 | 2018 |
| 15 |
Lc65 - Sample 1 - Follow-up 14
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2019 | 2019 |
| 16 |
Lc65 - Sample 1 - Follow-up 15
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Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2020 | 2020 |
The population is composed of non-institutionalized males and females aged 65 to 70 in 2009 (birth year 1939 to 1943) .
Selection Criteria
- Minimum age
-
65
- Maximum age
-
70
- Newborns
- Twins
- Countries
-
- Switzerland
- Territory
- Lausanne
- Ethnic Origin
-
- Health Status
-
- Individuals unable to respond due to cognitive impairment were excluded.
- Other Criteria
- Institutionalized individuals were excluded.
Recruitment
- Sources of recruitment
-
- General population
- General Population
-
- Selected sample
- Supplementary Information
-
The second stage of sampling and recruitment in the Lc65+ study took place in 2009, with a similar procedure to that followed in the first stage.
Number of Participants
- Number of Participants
- 1,489
- Number of Participants with Biological Samples
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
Lc65 - Sample 2 - Baseline
|
A self-completed questionnaire covered specific life course characteristics such as life history from childhood, through adulthood and until the time of completing the questionnaire (i.e. 65 to 70 ... | 2009 | 2010 |
| 2 |
Lc65 - Sample 2 - Follow-up 1
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2011 | 2011 |
| 3 |
Lc65 - Sample 2 - Follow-up 2
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2012 | 2012 |
| 4 |
Lc65 - Sample 2 - Follow-up 3
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2013 | 2013 |
| 5 |
Lc65 - Sample 2 - Follow-up 4
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2014 | 2014 |
| 6 |
Lc65 - Sample 2 - Follow-up 5
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2015 | 2015 |
| 7 |
Lc65 - Sample 2 - Follow-up 6
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2016 | 2016 |
| 8 |
Lc65 - Sample 2 - Follow-up 7
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2017 | 2017 |
| 9 |
Lc65 - Sample 2 - Follow-up 8
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2018 | 2018 |
| 10 |
Lc65 - Sample 2 - Follow-up 9
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2019 | 2019 |
| 11 |
Lc65 - Sample 2 - Follow-up 10
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2020 | 2020 |
The population is composed of non-institutionalized males and females aged 65 to 70 in 2014 (birth year 1944 to 1948).
Selection Criteria
- Minimum age
-
65
- Maximum age
-
70
- Newborns
- Twins
- Countries
-
- Switzerland
- Territory
- Lausanne
- Ethnic Origin
-
- Health Status
-
- Individuals unable to respond due to cognitive impairment were excluded.
- Other Criteria
- Institutionalized individuals were excluded.
Recruitment
- Sources of recruitment
-
- General population
- General Population
-
- Selected sample
- Supplementary Information
-
The third stage of sampling and recruitment in the Lc65+ study took place in 2014, with a similar procedure to that followed in the first and second stages. As participation rates were expected to decline over time and particularly in baby boomers, the number of invited persons was somewhat higher in sample 3.
Number of Participants
- Number of Participants
- 1,678
- Number of Participants with Biological Samples
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
Lc65 - Sample 3 - Baseline
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A self-completed questionnaire covered specific life course characteristics such as life history from childhood, through adulthood and until the time of completing the questionnaire (i.e. 65 to 70 ... | 2014 | 2015 |
| 2 |
Lc65 - Sample 3 - Follow-up 1
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2016 | 2016 |
| 3 |
Lc65 - Sample 3 - Follow-up 2
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2017 | 2017 |
| 4 |
Lc65 - Sample 3 - Follow-up 3
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2018 | 2018 |
| 5 |
Lc65 - Sample 3 - Follow-up 4
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2019 | 2019 |
| 6 |
Lc65 - Sample 3 - Follow-up 5
|
Follow-up yearly questionnaires repeated a large set of baseline questions to assess longitudinal changes (e.g. self-rated health status), but also introduced additional measures over time as they ... | 2020 | 2020 |
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
- Cognitive functioning
- Personality
- Psychological distress and emotions
- Other psychological measures and assessments
- Perception of health
- Quality of life
- Life course development
- Functional limitations
- Other perception of health, quality of life and functional limitation-related information
- Tobacco
- Alcohol
- Drugs
- Nutrition
- Breastfeeding
- Physical activity
- Sleep
- Sexual behaviours and orientation
- Technological devices
- Misbehaviour and criminality
- Other and unspecified lifestyle information
Socio-demographic and economic characteristics
Age/birthdate
Sex/gender
Marital/partner status
Family and household structure
Education
Residence
Birthplace
Citizenship and immigrant status
Language
Labour force and retirement
Income, possessions, and benefits
Lifestyle and behaviours
Tobacco
Alcohol
Nutrition
Physical activity
Sleep
Sexual behaviours and orientation
Leisure activities
Technological devices
Other and unspecified lifestyle information
Birth, pregnancy and reproductive health history
Puberty, menstruation, menopause and andropause
Perception of health, quality of life, development and functional limitations
Perception of health
Quality of life
Functional limitations
Use of assistive devices
Diseases
Certain infectious and parasitic diseases (A00-B99)
Neoplasms (C00-D48)
Endocrine, nutritional and metabolic diseases (E00-E90)
Mental and behavioural disorders (F00-F99)
Diseases of the nervous system (G00-G99)
Diseases of the circulatory system (I00-I99)
Diseases of the respiratory system (J00-J99)
Diseases of the digestive system (K00-K93)
Diseases of the skin and subcutaneous tissue (L00-L99)
Diseases of the musculoskeletal system and connective tissue (M00-M99)
Diseases of the genitourinary system (N00-N99)
Certain conditions originating in the perinatal period (P00-P96)
Injury, poisoning and certain other consequences of external causes (S00-T98)
External causes of morbidity and mortality (V01-Y98)
Diseases without precise specification or falling into multiple categories
Symptoms and signs
Symptoms and signs involving the circulatory and respiratory systems (R00-R09)
Symptoms and signs involving cognition, perception, emotional state and behaviour (R40-R46)
General symptoms and signs (R50-R69)
Symptoms related to multiple categories
Medication and supplements
Medication and supplement intake
Non-pharmacological interventions
Surgical interventions
Educational and health promotion interventions
Health and community care services utilization
Visits to health professionals
Hospitalizations
Community and social care
Other health and community care
Death
Vital status
Cause of death
Other end of life or death-related information
Physical measures and assessments
Physical characteristics
Anthropometry
Circulation and respiration
Muscles, skeleton and mobility
Sensory and pain
Cognition, personality and psychological measures and assessments
Cognitive functioning
Personality
Psychological distress and emotions
Other psychological measures and assessments
Life events, life plans, beliefs and values
Life events
Beliefs and values
Social environment and relationships
Social network
Social participation
Social support
Physical environment
Built environment/neighbourhood characteristics
Administrative information
Identifiers
Date and time-related information
Questionnaire and interview-related information
Physical and cognitive measure and biosample-related information
Data and sample collection center-related information
Other administrative information
Cognitive functioning
Clock Drawing Test
Mini-Mental State Examination
Trail Making Test
Verbal Fluency
Personality
Pearlin Mastery Scale
Psychological distress and emotions
General Health Questionnaire
Philadelphia Geriatric Center Morale Scale
Quality of life
Short-Form 12 Health Survey
Functional limitations
Activities of Daily Living
Falls Efficacy Scale
Fried Frailty Phenotype Criteria
Nutrition
Mini Nutritional Assessment