Lothian Birth Cohort 1936
The original aim of the LBC1936 study was to seek determinants of normal cognitive ageing in survivors of the Scottish Mental Survey 1947. Those determinants of lifetime cognitive ageing were to include genetic, information processing, medical, economic and psycho-social factors. Wave 2 of LBC1936 was intended to identify the mechanisms that cause white matter damage and how this causes cognitive decline with ageing. New to Wave 2 was that the LBC1936 subjects underwent detailed structural MRI brain scan.
- Start Year
- 2004
Visit LBC1936
| Investigators | Contacts |
|---|---|
|
|
Design
- Study design
- Cohort
- Follow Up
-
The LBC1936 participants undertook a general intelligence test at age 11 years and were recruited for the LBC1936 cohort at the mean age of 70. They have been examined at mean ages of 70, 73 and 76 years.
Marker Paper
Deary IJ, Gow AJ, Pattie A, Starr JM. Cohort profile: the Lothian Birth Cohorts of 1921 and 1936. Int J Epidemiol. 2012 Dec;41(6):1576-84.
PUBMED 22253310
Recruitment
- Recruitment Target
-
- Other : Sub-sample of the participants of the Scottish Mental Survey of 1947
Number of Participants
- Number of Participants
- 1,091
- Number of Participants with Biological Samples
- 1,091
- Supplementary Information
-
548 men and 543 women.
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
Timeline
LBC1936
A sub-sample of the Scottish Mental Survey 1947. The mean age of the participants was 70 years old at wave 1, 73 years old at wave 2 and 76 years old at wave 3.
Selection Criteria
- Newborns
- Twins
- Countries
-
- United Kingdom
- Territory
-
Edinburgh and the surrounding area.
- Other Criteria
-
Only the available participants who had completed all previous waves were invited.
Recruitment
- Sources of recruitment
-
- Participants from existing studies
- Participants from existing studies
- Supplementary Information
-
Between 2004 and 2007, individuals from Edinburgh and the Lothians who might have taken part in the 1947 Survey were invited to participate in the LBC1936.
- Participants from Existing Studies
-
- The Scottish Mental Survey 1947
Number of Participants
- Number of Participants
- 1,091
- Number of Participants with Biological Samples
- 1,091
- Supplementary Information about selection criteria
-
Wave 1: 1091 participants (548 men and 543 women)
Wave 2: 866 participants (448 men and 418 women)
Wave 3: 697 participants (360 men and 337 women)
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
LBC1936 - Wave 1
|
Cognitive ability: Moray House Test and psychometric battery consisting of executive function, reasoning, memory, and processing speed. Socio-demographic ... |
2004-01 | 2007-05 |
| 1 |
LBC1936 - Wave 2
|
Cognitive ability: Psychometric battery consisting of executive function, reasoning, memory, and processing speed. Socio-demographic information: marital ... |
2007-10 | 2010-05 |
| 2 |
LBC1936 - Wave 3
|
Cognitive ability: Psychometric battery consisting of executive function, reasoning, memory, and processing speed. Socio-demographic information: marital ... |
2011-07 | 2013-11 |
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
- Cognitive functioning
- Personality
- Psychological distress and emotions
- Other psychological measures and assessments
- Life events
- Beliefs and values
- Perception of health
- Quality of life
- Life course development
- Functional limitations
- Other perception of health, quality of life and functional limitation-related information
- Tobacco
- Alcohol
- Drugs
- Nutrition
- Breastfeeding
- Physical activity
- Sleep
- Sexual behaviours and orientation
- Technological devices
- Misbehaviour and criminality
- Other and unspecified lifestyle information
Socio-demographic and economic characteristics
Lifestyle and behaviours
Birth, pregnancy and reproductive health history
Perception of health, quality of life, development and functional limitations
Diseases
Symptoms and signs
Medication and supplements
Non-pharmacological interventions
Health and community care services utilization
Death
Physical measures and assessments
Laboratory measures
Cognition, personality and psychological measures and assessments
Life events, life plans, beliefs and values
Social environment and relationships
Physical environment
Administrative information
Cognitive functioning
Personality
Psychological distress and emotions
Beliefs and values
Quality of life
Other perception of health, quality of life and functional limitation-related information
Nutrition
Sleep