Hertfordshire Ageing Study
The principal objective of the HAS is to examine life course influences on healthy ageing. The outcomes of interest are sarcopenia, frailty, falls, physical performance and cognitive function. The main potential determinants of healthy ageing under investigation are intra-uterine and post-natal size and growth, genetic characteristics and adult physical activity, diet, lifestyle and socioeconomic status.
- Start Year
- 1920
Visit HAS
| Investigators | Contacts |
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Design
- Study design
- Cohort
- Follow Up
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The NHSCR (National Health Service Central Register) was used to trace 6,803 men and women born in North Hertfordshire between 1920 and 1930, for whom birth and infancy data had been recorded. The NHSCR identified 2,621 men and women as resident in the UK in 1994; 1,428 of these were still resident in North Hertfordshire. With permission from their GP, we invited these men and women to participate in a home interview and clinic at which a wide panel of markers of ageing were characterised (including grip strength, cognitive function, anthropometry, visual acuity and lens opacity, hearing threshold and skin thickness). This first HAS follow-up was conducted between 1994 and 1995 when the participants ranged in age from 63 to 73 years. A second follow-up was conducted in 2003-05, a median of 9 years after the first follow-up, when participants were aged 72-83 years.
- Supplementary Information
Marker Paper
Syddall HE, Simmonds SJ, Martin HJ, Watson C, Dennison EM, Cooper C, Sayer AA; Hertfordshire Cohort Study Group. Cohort profile: The Hertfordshire Ageing Study (HAS). Int J Epidemiol. 2010 Feb;39(1):36-43. doi: 10.1093/ije/dyn275.
PUBMED 19131391
Recruitment
- Recruitment Target
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- Individuals
Number of Participants
- Number of Participants
- 1,428
- Number of Participants with Biological Samples
- 717
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
Timeline
HAS - Population
The HAS population consists of 1,428 live singleton births in North Hertfordshire between 1920 and 1930.
Selection Criteria
- Newborns
- Twins
- Countries
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- United Kingdom
- Territory
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North Hertfordshire
- Ethnic Origin
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- Health Status
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Recruitment
- Sources of recruitment
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- General population
- General Population
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- Selected sample
Number of Participants
- Number of Participants
- 1,428
- Number of Participants with Biological Samples
- 717
- Supplementary Information about selection criteria
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Baseline: 1428 individuals
Follow-up 1: Target population: 1428 individuals residing in North Hertfordshire: 824 participants for the interview of which 717 with biological samples.
Follow-up 2: Target population: 717 individuals with biological samples from follow-up 1: 359 participants for the interview of which 294 with biological samples.
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
HAS - Baseline
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Baseline assessment of participants during the age of 0-5 years. Early life measures (weight at birth, method of infant feeding, weight at one year of age, illness and development to ... |
1920 | 1930 |
| 1 |
HAS - Follow-up 1
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The first HAS follow-up was conducted in 1994-95 when the participants' age ranged from 63 to 73 years. Data were collected from home interview and clinic assessment and cover an extensive ... |
1994 | 1995 |
| 2 |
HAS - Follow-up 2
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The second formal follow-up was conducted in 2003-05 when participant members of the cohort were aged 72-83 years. Data were collected from home interview and clinic assessment and cover ... |
2003 | 2005 |
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
- Cognitive functioning
- Personality
- Psychological distress and emotions
- Other psychological measures and assessments
- Life events
- Beliefs and values
- Perception of health
- Quality of life
- Life course development
- Functional limitations
- Other perception of health, quality of life and functional limitation-related information
- Tobacco
- Alcohol
- Drugs
- Nutrition
- Breastfeeding
- Physical activity
- Sleep
- Sexual behaviours and orientation
- Technological devices
- Misbehaviour and criminality
- Other and unspecified lifestyle information
Socio-demographic and economic characteristics
Lifestyle and behaviours
Birth, pregnancy and reproductive health history
Perception of health, quality of life, development and functional limitations
Diseases
Symptoms and signs
Medication and supplements
Non-pharmacological interventions
Health and community care services utilization
Death
Physical measures and assessments
Laboratory measures
Cognition, personality and psychological measures and assessments
Life events, life plans, beliefs and values
Preschool, school and work life
Social environment and relationships
Physical environment
Administrative information
Cognitive functioning
Personality
Psychological distress and emotions
Beliefs and values
Quality of life
Functional limitations
Nutrition