Determinants of Community COVID-19 Transmission: Learning from the Hutterites
Networks
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Datasets
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Variables
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The overall goal of this study is to understand the community determinants of COVID-19 transmission.
Specific objectives are:
* To determine if pre-existing SARS- CoV-2 antibodies in children prevents subsequent infection in others (i.e. is there a herd effect),
* To define longitudinal SARS-CoV-2 viral load in children and its relationship to colony transmission,
* To determine the role of physical distancing in COVID-19 colony transmission,
* To assess the diagnostic accuracy of respiratory and serological specimens that are being used to detect COVID-19,
* To determine the effect of influenza on SARS-CoV-2 infection at the individual and community level,
* To assess re-introduction of SARS-CoV-2 viruses in colonies by whole genome sequencing.
- Start Year
- 2021
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Design
- Study design
- Cohort
- Follow Up
- In the main phase, colonies or participants are followed-up biweekly over 2 to 6 month (surveillance), at mid-point and at the end of the trial. In the extension phase, enrolled colonies and new colonies/participants are followed-up weekly for up to 3 months (active surveillance) and at the end of the trial. In the Omicron variant extension phase, enrolled colonies or participants are followed-up weekly for up to 6 months (active surveillance), at mid-point and at the end of the study.
Recruitment
- Recruitment Target
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- Other : Hutterite colonies living in Alberta and in Saskatchewan
Number of Participants
- Number of Participants
- 2,065
- Number of Participants with Biological Samples
- Supplementary Information
- This study was conducted in 20 Hutterite colonies in which the mean population size of the study colonies is 103 (range 62 to 143) members, with on average 24 households per colony.
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
Timeline
Populations
The population is composed of all Hutterite colony members, of any age, who are living in Alberta and in Saskatchewan.
Selection Criteria
- Newborns
- Twins
- Countries
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- Canada
- Territory
- Ethnic Origin
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- Hutterite
- Health Status
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- Supplementary Information about selection criteria
- Participants are either from one of the 15 colonies in Alberta or from one of the 5 colonies in Saskatchewan.
Recruitment
- Sources of recruitment
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- Specific population
- Specific Population
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- Other specific population : Hutterite colonies
- Supplementary Information
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Surveillance research assistants kept in communication with Hutterite colony members, after a close collaboration of at least 3 years with them and 10 colonies participated.
Number of Participants
- Number of Participants
- 697
- Number of Participants with Biological Samples
- Supplementary Information about selection criteria
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
DCCT - Main Cohort - Baseline
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Information about demographic (age, sex), past medical history (comorbidities), current medications, history of prior influenza immunization, COVID vaccination was collected. Blood (serum sample) ... | 2021-01 | 2021-01 |
| 1 |
DCCT - Main Cohort - Surveillance
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Information about signs and symptoms of COVID-19 was collected biweekly through telephone calls. A swab was collected if the participants reports a set of symptoms (two or more of the following: ... | 2021-01 | 2021-06 |
| 2 |
DCCT - Main Cohort - Mid-point serology
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Blood samples were collected. Mid-point blood collection will be omitted if baseline blood collection to end of study duration is 4 months or less. | 2021-03 | 2021-03 |
| 3 |
DCCT - Main Cohort - Final serology
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Blood samples were collected. | 2021-06 | 2021-06 |
The population is composed of both enrolled colonies of Hutterite in the main cohort and new colonies who are living in Alberta and in Saskatchewan.
Selection Criteria
- Newborns
- Twins
- Countries
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- Canada
- Territory
- Ethnic Origin
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- Hutterite
- Health Status
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- Supplementary Information about selection criteria
- Participants are either from one of the 15 colonies in Alberta or from one of the 5 colonies in Saskatchewan.
Recruitment
- Sources of recruitment
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- Specific population
- Specific Population
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- Other specific population : Hutterite colonies
- Supplementary Information
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Participants are recruited from 16 colonies: some continuing colonies from the main cohort and some new colonies.
Number of Participants
- Number of Participants
- 1,332
- Number of Participants with Biological Samples
- Supplementary Information about selection criteria
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Continuing colonies: 697 participants
New colonies: 635 participants
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
DCCT - Extension Cohort - Baseline
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Information about demographic (age, sex), past medical history (comorbidities), current medications, history of prior influenza immunization, COVID vaccination was collected for new participants ... | 2021-07 | 2021-07 |
| 1 |
DCCT - Extension Cohort - Surveillance
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Information about symptoms that were reported daily in a diary; physical distancing report completed by field staff; COVID-19 vaccinations status was collected during active surveillance. Nasal ... | 2021-07 | 2021-10 |
| 2 |
DCCT - Extension Cohort - Final serology
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Blood samples were collected. | 2021-10 | 2021-10 |
The population is composed of all Hutterite colony members, of any age, who are living in Alberta and in Saskatchewan under the emergence of the omicron variant of SARS-CoV-2 virus.
Selection Criteria
- Newborns
- Twins
- Countries
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- Canada
- Territory
- Ethnic Origin
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- Hutterite
- Health Status
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- Supplementary Information about selection criteria
- Participants are either from one of the 15 colonies in Alberta or from one of the 5 colonies in Saskatchewan.
Recruitment
- Sources of recruitment
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- Specific population
- Specific Population
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- Other specific population : Hutterite colonies
- Supplementary Information
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Participants are recruited from 14 continuing colonies.
Number of Participants
- Number of Participants
- 1,198
- Number of Participants with Biological Samples
- Supplementary Information about selection criteria
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
DCCT - Omicron Variant Cohort - Baseline
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Information about demographic (age, sex), past medical history (comorbidities), current medications, history of prior influenza immunization, COVID vaccination was collected. Blood samples were ... | 2022-01 | 2022-01 |
| 1 |
DCCT - Omicron Variant Cohort - Surveillance
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Information about symptoms reported daily in a diary; physical distancing report completed by field staff and COVID-19 vaccinations in real-time will be collected. Nasal swabs will be collected ... | 2022-01 | 2022-09 |
| 2 |
DCCT - Omicron Variant Cohort - Mid-point serology
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Blood samples will be collected. | 2022-05 | 2022-05 |
| 3 |
DCCT - Omicron Variant Cohort - Final serology
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Blood samples will be collected. | 2022-10 | 2022-10 |
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
Socio-demographic and economic characteristics
Age/birthdate
Sex/gender
Family and household structure
Residence
Lifestyle and behaviours
Tobacco
Perception of health, quality of life, development and functional limitations
Perception of health
Diseases
Certain infectious and parasitic diseases (A00-B99)
Neoplasms (C00-D48)
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Endocrine, nutritional and metabolic diseases (E00-E90)
Diseases of the nervous system (G00-G99)
Diseases of the circulatory system (I00-I99)
Diseases of the respiratory system (J00-J99)
Diseases of the digestive system (K00-K93)
Diseases of the genitourinary system (N00-N99)
Diseases without precise specification or falling into multiple categories
Symptoms and signs
Medication and supplements
Non-pharmacological interventions
Laboratory diagnosis interventions
Health and community care services utilization
Hospitalizations
Physical measures and assessments
Anthropometry
Laboratory measures
Virology
Immunology
Administrative information
Identifiers
Date and time-related information
Questionnaire and interview-related information
Physical and cognitive measure and biosample-related information
Other administrative information