COVID-19 Infections in MS & Related Diseases
Networks
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Datasets
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Variables
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The COViMS (COVID-19 Infections in MS & Related Diseases) registry is a joint effort of the National MS Society, the Consortium of MS Centers and the Multiple Sclerosis Society of Canada.
The objective of the registry is to define the impact of COVID-19 on patients with MS and other CNS demyelinating diseases (Neuromyelitis Optica Spectrum Disease, or MOG antibody disease) who have developed COVID-19.
- Start Year
- 2020
- End Year
- 2022
- Supplementary Information
Visit COViMS
| Investigators | Contacts |
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Design
- Study design
- Registry
- Follow Up
- Supplementary Information
- * To enable ease of information sharing, COViMS Registry data collection was harmonized with the Global Data Sharing ini-tiative acquiring information on SARS-CoV-2 infection world-wide. * This registry has been determined "not human subjects research" under US Federal Guidelines by the IRB at Washington University in St. Louis. The database contains only de-identified data, in accordance with HIPAA Safe Harbor De-Identification standards.
Marker Paper
Salter A, Fox RJ, Newsome SD, et al. Outcomes and Risk Factors Associated With SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis. JAMA Neurol. 2021 Jun 1;78(6):699-708. doi: 10.1001/jamaneurol.2021.0688. Erratum in: JAMA Neurol. 2021 Jun 1;78(6):765.
PUBMED 33739362
Recruitment
- Recruitment Target
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- Individuals
Number of Participants
- Number of Participants
- 5,208
- Number of Participants with Biological Samples
- Supplementary Information
- * 4602 participants had a positive laboratory result. * 606 participants were suspected but not confirmed positive cases.
Access
Availability of data and biosamples
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| Possible Access to Biosamples | |
| Other |
Availability of access information
On the study website : https://www.covims.org/
Timeline
COViMS population
The population is composed of patients with multiple sclerosis and related diseases who had laboratory-positive for SARS-CoV-2 or are highly suspected to be infected with SARS-CoV-2.
Selection Criteria
- Newborns
- Twins
- Countries
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- Canada
- United States of America
- Mexico
- Ethnic Origin
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- white
- Black or African American
- Asian
- American Indian, Alaska Native or Indigenous Canadian
- Native Hawaiian or Other Pacic Islander
- Other
- Health Status
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- Inclusion criteria : * Patients with multiple sclerosis and related diseases. * Laboratory confirmed COVID patients. * Suspected COVID-19 patients but not confirmed who have fever with following symptoms or diseases; Dry cough, +/- anorexia, myalgias, dyspnea, anosmia/ageusia and potential exposure.
- Supplementary Information about selection criteria
Recruitment
- Sources of recruitment
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- Specific population
- Specific Population
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- Clinic patients
- Supplementary Information
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Health care providers were asked to report patients for SARS-CoV-2 infection after a minimum of 7 days from initial infectious symptom onset and when sufficient time had passed to observe the COVID-19 disease course through resolution of acute illness or death.
Number of Participants
- Number of Participants
- 5,208
- Number of Participants with Biological Samples
Data Collection Event
Information on socio-demographic caracteristics, multiple sclerosis disease characteristics including multiple sclerosis disease duration and ambulation milsetones (fully ambulatory, walks with assistance, nonambulatory), comorbid conditions, cigarette use history and glucocorticoid treatment during the prior two months are collected. Information on time of SARS-CoV-2 infection and reinfection, symptoms, vaccination status and treatments is collected. Previous laboratory and radiological data, pregnant and post partum status, hospitalization and admission to intensive care unit, ventilation support use and vital status is also collected.
Height and weight measurements are collected.
- Start Date
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2020-04
- Data sources
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- Questionnaires
- Physical measures
- Other : Health care providers
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
Socio-demographic and economic characteristics
Age/birthdate
Sex/gender
Residence
Ethnicity, race and religion
Labour force and retirement
Lifestyle and behaviours
Tobacco
Drugs
Birth, pregnancy and reproductive health history
Pregnancy, delivery and birth
Perception of health, quality of life, development and functional limitations
Functional limitations
Diseases
Certain infectious and parasitic diseases (A00-B99)
Neoplasms (C00-D48)
Diseases of the nervous system (G00-G99)
Diseases of the respiratory system (J00-J99)
Diseases without precise specification or falling into multiple categories
Symptoms and signs
Symptoms and signs involving nervous and musculoskeletal systems (R25-R29)
Symptoms related to multiple categories
Medication and supplements
Medication and supplement intake
Non-pharmacological interventions
Radiological interventions
Laboratory diagnosis interventions
Other and unspecified non-pharmacological interventions
Health and community care services utilization
Visits to health professionals
Hospitalizations
Other health and community care
Death
Cause of death
Physical measures and assessments
Anthropometry
Circulation and respiration
Laboratory measures
Hematology
Virology
Preschool, school and work life
Work life
Administrative information
Identifiers
Physical and cognitive measure and biosample-related information
Other administrative information