Individual Study / CONSTANCES

Cohorte des consultants des Centres d'examens de santé

Cohorte des consultants des Centres d'examens de santé

Networks -
Datasets -
Variables -
Start Year
2012
Visit CONSTANCES

Members

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Investigators Contacts
  • Dr. Marie Zins
    Institut national de la santé et de la recherche médicale (INSERM)
  • Dr. Marcel Goldberg
    Institut national de la santé et de la recherche médicale (INSERM)
  • Dr. Marcel Goldberg
    Institut national de la santé et de la recherche médicale (INSERM)
  • Dr. Marie Zins
    Institut national de la santé et de la recherche médicale (INSERM)

Design

Study design
Cohort
Follow Up

The self-administered questionnaire is sent annually. Participants are also asked to go to the Health Screening Center every four years for medical and laboratory examinations. Moreover, health and socio-professional data, along with causes of death, are regularly retrieved from the national health insurance, retirement pension fund and mortality databases.

Supplementary Information

Marker Paper

Zins M, Goldberg M, and the CONSTANCES team. The French CONSTANCES population-based cohort: design, inclusion and follow-up. Eur J Epidemiology. 2015, 30:1317-1328

PUBMED 26520638

Recruitment

Recruitment Target
  • Individuals

Number of Participants

Number of Participants
220,000
Number of Participants with Biological Samples
39,000
Supplementary Information

Access

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other
Possible to collect additional data from cohort participants.

Timeline

CONSTANCES population

Selection Criteria
Minimum age
18
Maximum age
69
Newborns
Twins
Countries
  • France
Ethnic Origin
Health Status

Recruitment

Sources of recruitment
  • General population
General Population
  • Selected sample
Supplementary Information

Participants are drawn randomly from the persons covered by the French National Health Insurance Fund (CNAM). Everyone with health insurance from CNAM as well as their dependents, is entitled to receive health examinations that include free extensive work-ups conducted in selected Health Screening Centers (HSCs). Randomly selected persons received an invitation to come to their HSC for inclusion in the CONSTANCES cohort. Inclusion in CONSTANCES took place over a 6-year period (2012-2019).

Number of Participants

Number of Participants
220,000
Number of Participants with Biological Samples
39,000
Supplementary Information about selection criteria
Inclusion: 8000 participants
Follow-up 2013: 20 000 participants
Follow-up 2014: 25 000 participants
Follow-up 2015: 32 000 participants
Follow-up 2016: 40 000 participants
Follow-up 2017: 150 000 participants
Follow-up 2018: 185 000 participants
Follow-up 2019: 220 000 participants
Data Collection Events
# Name Description Start End
0 CONSTANCES - Inclusion version 1

Information was collected through a questionnaire and a Health Screening Center (HSC) visit for a comprehensive health examination. Information was collected on health and lifestyle as well as ...

2012 2014
1 CONSTANCES - Inclusion version 2

Information was collected through a questionnaire and a Health Screening Center (HSC) visit for a comprehensive health examination. Information was collected on health and lifestyle as well as ...

2013 2016
2 CONSTANCES - Follow-up 2013 - w1

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, ...

2013-05 2013-10
3 CONSTANCES - Follow-up 2013 - w2

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, ...

2013-11 2014-04
4 CONSTANCES - Follow-up 2014

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, ...

2014-05 2015-04
5 CONSTANCES - Inclusion version 3

Information was collected through a questionnaire and a Health Screening Center (HSC) visit for a comprehensive health examination. Information was collected on health and lifestyle as well as ...

2015 2019
6 CONSTANCES - Follow-up 2015

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, ...

2015-05 2016-04
7 CONSTANCES - Follow-up 2016 - w1

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, ...

2016-05 2016-10
8 CONSTANCES - Follow-up 2016 - w2

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, ...

2016-11 2017-04
9 CONSTANCES - Follow-up 2017

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, ...

2017-05 2018-04
10 CONSTANCES - Health exam

At the Health Center, an evaluation of specific health problems of the elderly is performed and comprises the Instrumental Activities of Daily Living questionnaire, the French ...

2017-05 2019-11
11 CONSTANCES - Follow-up 2018

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, ...

2018-05 2019-04
12 CONSTANCES - Follow-up 2019

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, ...

2019-05 2020-04
13 CONSTANCES - Follow-up 2020 The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, socioeconomic ... 2020-09 2021-05

Classifications

Socio-demographic and economic characteristics
Lifestyle and behaviours
Birth, pregnancy and reproductive health history
Perception of health, quality of life, development and functional limitations
Diseases
Symptoms and signs
Medication and supplements
Non-pharmacological interventions
Health and community care services utilization
Death
Physical measures and assessments
Laboratory measures
Cognition, personality and psychological measures and assessments
Life events, life plans, beliefs and values
Preschool, school and work life
Social environment and relationships
Physical environment
Administrative information
Cognitive functioning
Personality
Psychological distress and emotions
Other psychological measures and assessments
Perception of health
Quality of life
Life course development
Functional limitations
Other perception of health, quality of life and functional limitation-related information
Tobacco
Alcohol
Drugs
Nutrition
Breastfeeding
Physical activity
Sleep
Sexual behaviours and orientation
Technological devices
Misbehaviour and criminality
Other and unspecified lifestyle information

Socio-demographic and economic characteristics

Age/birthdate
Sex/gender
Marital/partner status
Family and household structure
Education
Citizenship and immigrant status
Ethnicity, race and religion
Language
Labour force and retirement
Income, possessions, and benefits

Lifestyle and behaviours

Tobacco
Alcohol
Drugs
Nutrition
Breastfeeding
Physical activity
Transportation
Sleep
Sexual behaviours and orientation
Technological devices

Birth, pregnancy and reproductive health history

Puberty, menstruation, menopause and andropause
Contraception
Pregnancy, delivery and birth
Fertility and sexual health

Perception of health, quality of life, development and functional limitations

Perception of health
Quality of life
Functional limitations

Diseases

Certain infectious and parasitic diseases (A00-B99)
Neoplasms (C00-D48)
Endocrine, nutritional and metabolic diseases (E00-E90)
Mental and behavioural disorders (F00-F99)
Diseases of the nervous system (G00-G99)
Diseases of the eye and adnexa (H00-H59)
Diseases of the ear and mastoid process (H60-H95)
Diseases of the circulatory system (I00-I99)
Diseases of the respiratory system (J00-J99)
Diseases of the digestive system (K00-K93)
Diseases of the skin and subcutaneous tissue (L00-L99)
Diseases of the musculoskeletal system and connective tissue (M00-M99)
Diseases of the genitourinary system (N00-N99)
Pregnancy, childbirth and the puerperium (O00-O9A)
Congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
Injury, poisoning and certain other consequences of external causes (S00-T98)
External causes of morbidity and mortality (V01-Y98)
Diseases without precise specification or falling into multiple categories

Symptoms and signs

Symptoms and signs involving the circulatory and respiratory systems (R00-R09)
Symptoms and signs involving the digestive system and abdomen (R10-R19)
Symptoms and signs involving the urinary system (R30-R39)
Symptoms and signs involving cognition, perception, emotional state and behaviour (R40-R46)
General symptoms and signs (R50-R69)
Symptoms related to multiple categories

Medication and supplements

Medication and supplement intake
Posology and protocol of administration

Non-pharmacological interventions

Surgical interventions
Radiological interventions
Laboratory diagnosis interventions
Other and unspecified non-pharmacological interventions

Health and community care services utilization

Visits to health professionals
Hospitalizations
Community and social care

Physical measures and assessments

Anthropometry

Cognition, personality and psychological measures and assessments

Psychological distress and emotions
Other psychological measures and assessments

Life events, life plans, beliefs and values

Life events
Beliefs and values

Preschool, school and work life

Work life

Social environment and relationships

Social network
Social participation
Social support
Other social environment characteristics

Physical environment

Workplace characteristics
Other physical environment characteristics

Administrative information

Identifiers
Date and time-related information
Questionnaire and interview-related information
Other administrative information

Psychological distress and emotions

Center for Epidemiological Studies Depression Scale
SCOFF Questionnaire

Quality of life

Short-Form 12 Health Survey

Functional limitations

Instrumental Activities of Daily Living

Alcohol

Alcohol Use Disorders Identification Test

Nutrition

Food Frequency Questionnaire (different forms)

Sleep

Epworth Sleepiness Scale
Jenkins Sleep Scale