CHILD Cohort Study
- Start Year
- 2008
Visit CHILD
| Investigators | Contacts |
|---|---|
|
|
Design
- Study design
- Cohort
- Follow Up
- After recruitment, participants are followed at 36 weeks, at birth, and 3 months, 6 months, 1 year, 1.5 years, 2 years, 2.5 years, 3 years, 4 years, 5 years, 8 years and 12 years postpartum.
- Supplementary Information
Marker Paper
Subbarao P, Anand SS, Becker AB, et al. The Canadian Healthy Infant Longitudinal Development (CHILD) Study: examining developmental origins of allergy and asthma. Thorax. 2015 Oct;70(10):998-1000. doi: 10.1136/thoraxjnl-2015-207246. Epub 2015 Jun 11.
PUBMED 26069286
Recruitment
- Recruitment Target
-
- Families
Number of Participants
- Number of Participants
- 9,875
- Number of Participants with Biological Samples
- 9,464
- Supplementary Information
-
Mothers: 3579 participants
Fathers: 2841 participants
Children: 3455 participants
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
Availability of access information
By contacting the study representative
Sector of research
| Possible Access to Data | Possible Access to Biosamples | |
|---|---|---|
| Investigators from the public sector | ||
| Investigators from the private sector | ||
| Investigators from not-for-profit organization |
If an industry partner or private sector researcher are interested in working with the CHILD Cohort study, the study takes a collaborative research approach whereas the industry partner or private sector researcher is linked up with a CHILD Cohort Study Executive or Advisory Board member.
Transfer
| Possible Access to Data | Possible Access to Biosamples | |
|---|---|---|
| Can leave the study facility | ||
| Can leave the country |
All Investigators must apply to access CHILD data and samples, and sign a Materials and Information Transfer Agreement, which includes the conditions for access.
Cost
| Possible Access to Data | Not yet defined |
| Possible Access to Biosamples | Fixed Cost |
Cost reduction for co-analyses
| Possible Access to Data | |
| Possible Access to Biosamples |
larger sample numbers allow better pricing from analysis labs
Timeline
Populations
Selection Criteria
- Sex
-
Women
- Minimum age
-
18
- Pregnant Women
-
- Second trimester
- Third trimester
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Vancouver, Edmonton, Winnipeg, Morden, Winkler, Toronto
- Ethnic Origin
-
- Health Status
-
- Other Criteria
- Second or third trimester of pregnancy
- Supplementary Information about selection criteria
- Approximately 25% non-Caucasian families
Recruitment
- Sources of recruitment
-
- General population
- Specific population
- General Population
-
- Volunteer enrolment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Parents are recruited at routine antenatal obstetrical ultrasound visits, person to person referrals, social media advertising, at kiosks at community events, malls and baby shows, and in health care locations.
Number of Participants
- Number of Participants
- 3,579
- Number of Participants with Biological Samples
- 3,487
- Supplementary Information about selection criteria
- 82 children failed inclusion criteria or met exclusion criteria at birth resulting in 3542 eligible mothers for follow-up.
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
CHILD - Mothers - 18 weeks gestation
|
At 18 weeks the mothers answered questionnaires concerning their profile, health, nutrition, vitamins, medications and stress. Household exposures were assessed using a home environment ... |
2008-01 | 2012-12 |
| 1 |
CHILD - Mothers - 36 weeks gestation
|
At 36 weeks the mothers answered a psychosocial questionnaire, collecting information about socioeconomic status, stress, depressive symptoms and social relationships. A mother life stress ... |
2008-05 | 2013-04 |
| 2 |
CHILD - Mothers - Birth
|
At the time of birth, the mothers answered a questionnaire concerning their medications. |
2008-05 | 2013-05 |
| 3 |
CHILD - Mothers - 3 months postpartum
|
At 3 months postpartum, mothers answered questionnaires concerning their profile/residence, nutrition, vitamins and supplements, and medications. A breast milk sample was collected. |
2008-08 | 2013-08 |
| 4 |
CHILD - Mothers - 6 months postpartum
|
At 6 months postpartum, the mothers answered questionnaires concerning their medications and level of stress. |
2008-11 | 2013-11 |
| 5 |
CHILD - Mothers - 1 year postpartum
|
At 1 year postpartum, the mothers answered questionnaires concerning their profile/residence, health, nutrition, vitamins and supplements, medications and socio-economic status. Maternal ... |
2009-05 | 2014-05 |
| 6 |
CHILD - Mothers - 1.5 years postpartum
|
At 1.5 years postpartum, the mothers answered a questionnaire concerning their level of stress. | 2009-11 | 2014-11 |
| 7 |
CHILD - Mothers - 2 years postpartum
|
At 2 years postpartum, the mothers answered questionnaires concerning their profile/residence, stress and parenting stress. | 2010-05 | 2015-05 |
| 8 |
CHILD - Mothers - 2.5 years postpartum
|
At 2.5 years postpartum, the mothers answered a questionnaire concerning their level of stress. |
2010-11 | 2015-11 |
| 9 |
CHILD - Mothers - 3 years postpartum
|
At 3 years postpartum, the mothers answered questionnaires concerning their profile/residence and socio-economic status. Maternal psychosocial characteristics were assessed by self-report which ... |
2011-05 | 2016-05 |
| 10 |
CHILD - Mothers - 4 years postpartum
|
At 4 years postpartum, the mothers answered questionnaires concerning their profile/residence and socio-economic status. Maternal psychosocial characteristics were assessed by self-report which ... |
2012-05 | 2017-05 |
| 11 |
CHILD - Mothers - 5 years postpartum
|
At 5 years postpartum, the mothers answered questionnaires concerning their profile/residence, health, nutrition, vitamins and supplements, medications and socio-economic status. Maternal ... |
2013-05 | 2018-05 |
| 12 |
CHILD - Mothers - 8 years postpartum
|
At 8 years postpartum, the mothers answered questionnaires concerning their profile/residence, health, nutrition, vitamins and supplements, medications and socio-economic status. Maternal ... |
2018-08 | 2020-12 |
| 13 |
CHILD - Mothers - 12 years postpartum
|
Information on profile/residence, health, nutrition and socio-economic status are collected. Maternal psychosocial characteristics are assessed by self-report which included stress, and parenting ... | 2021-01 |
Selection Criteria
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Vancouver, Edmonton, Winnipeg, Morden, Winkler, Toronto
- Ethnic Origin
-
- Health Status
-
- Apparently healthy children
- Other Criteria
- Premature, in vitro and children that were expected to spend less than 80% of their time in the primary home or if there was any expectation to move away from a recruitment center within 1 year were excluded. Children with major congenital abnormalities or respiratory distress syndrome, or children of multiple births were excluded as well.
Recruitment
- Sources of recruitment
-
- Specific population
- Specific Population
-
- Other specific population : Children of mothers who were participating in the study when they were born.
Number of Participants
- Number of Participants
- 3,455
- Number of Participants with Biological Samples
- 3,417
- Supplementary Information about selection criteria
- The number of participants with biological samples varies depending on the nature of sample and time point for collection (range 2000-3300).
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
CHILD - Children - Birth
|
At birth, the parents answered questionnaires concerning the child delivery and his medication intake. A nitric oxide test was also performed. During this visit a meconium/stool ... |
2008-05 | 2012-05 |
| 1 |
CHILD - Children - 3 months postpartum
|
At 3 months postpartum, the parents answered questionnaires concerning the child's health, nutrition and diet, and medications. Household exposures were assessed using a home environment ... |
2008-08 | 2013-08 |
| 2 |
CHILD - Children - 6 months postpartum
|
At 6 months postpartum, the parents answered questionnaires concerning the child's health, nutrition and diet, and medications. Household exposures were assessed using a home environment ... | 2008-11 | 2013-11 |
| 3 |
CHILD - Children - 1 year postpartum
|
At 1 year postpartum, the parents answered questionnaires concerning the child's health, nutrition and diet, and medications. Household exposures were assessed using a home environment ... |
2009-05 | 2014-05 |
| 4 |
CHILD - Children - 1.5 years postpartum
|
At 1.5 years postpartum, the parents answered questionnaires concerning the child's health, nutrition and diet, and medications. Household exposures were assessed using a home environment ... |
2009-11 | 2014-11 |
| 5 |
CHILD - Children - 2 years postpartum
|
At 2 years postpartum, the parents answered questionnaires concerning the child's health, nutrition and diet, and medications. Household exposures were assessed using a home environment questionnaire | 2010-05 | 2015-05 |
| 6 |
CHILD - Children - 2.5 years postpartum
|
At 2.5 years postpartum, the parents answered questionnaires concerning the child's health, nutrition and diet, and medications. Household exposures were assessed using a home environment ... |
2010-11 | 2015-11 |
| 7 |
CHILD - Children - 3 years postpartum
|
At 3 years postpartum, the parents answered questionnaires concerning the child's health, nutrition and diet, and medications. Household exposures were assessed using a home environment ... |
2011-05 | 2016-05 |
| 8 |
CHILD - Children - 4 years postpartum
|
At 4 years postpartum, the parents answered questionnaires concerning the child's health, nutrition and diet, and medications. Household exposures were assessed using a home environment ... | 2012-05 | 2017-05 |
| 9 |
CHILD - Children - 5 years postpartum
|
At 5 years postpartum, the parents answered questionnaires concerning the child's health, nutrition and diet, and medications. Household exposures were assessed using a home environment ... |
2013-05 | 2018-05 |
| 10 |
CHILD - Children - 8 years postpartum
|
At 8 years postpartum, the parents answered questionnaires concerning the child's health, nutrition and diet, medications, behavior, sleep and stress. Children completed questionnaires ... |
2018-08 | 2020-12 |
| 12 |
CHILD - Children - 12 years postpartum
|
Health, nutrition and diet, medications, behavior (child behaviour checklist), sleep and stress. Children complete questionnaires concerning physical activity, bullying, depression and anxiety ... | 2021-01 |
Selection Criteria
- Sex
-
Men
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Vancouver, Edmonton, Winnipeg, Morden, Winkler, Toronto
- Ethnic Origin
-
- Health Status
-
- Supplementary Information about selection criteria
- Participation of fathers is not a mandatory requirement. Fathers were eligible to join the study at any time during follow-up.
Recruitment
- Sources of recruitment
-
- Specific population
- Specific Population
-
- Other specific population : Partners of the women and fathers of the children who were recruited to participate in the CHILD study.
- Supplementary Information
-
Fathers are recruited at routine antenatal obstetrical ultrasound visits, person to person referrals, social media advertising, at kiosks at community events, malls and baby shows, and in health care locations.
Number of Participants
- Number of Participants
- 2,841
- Number of Participants with Biological Samples
- 2,560
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
CHILD - Fathers - 18 weeks gestation
|
At 18 weeks gestation, fathers answered questionnaires concerning their health and socio-economic status. Information about medication and supplements was also collected. A skin prick ... |
2008-01 | 2012-12 |
| 1 |
CHILD - Fathers - 1 year postpartum
|
At 1 year postpartum, fathers answered a questionnaire concerning their socio-economic status. If samples were not collected during the prenatal visit, a blood (whole blood, plasma, ... |
2009-05 | 2014-05 |
| 2 |
CHILD - Fathers - 5 years postpartum
|
At 5 years postpartum, fathers answered questionnaires concerning their health and socio-economic status. |
2013-05 | 2018-05 |
| 3 |
CHILD - Fathers - 8 years postpartum
|
At 8 years postpartum, fathers answered questionnaires concerning their health and acitivity habits. A clinical assessment was also completed. If samples were not collected during the ... |
2018-08 | 2020-12 |
| 4 |
CHILD - Fathers - 12 years postpartum
|
Information is collected on socioeconomic status, eating habits, health, stress, and home environment. A spirometry test is performed. The body composition is also measured. Blood and saliva ... | 2021-01 |
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
- Cognitive functioning
- Personality
- Psychological distress and emotions
- Other psychological measures and assessments
- Life events
- Beliefs and values
- Perception of health
- Quality of life
- Life course development
- Functional limitations
- Other perception of health, quality of life and functional limitation-related information
- Tobacco
- Alcohol
- Drugs
- Nutrition
- Breastfeeding
- Physical activity
- Sleep
- Sexual behaviours and orientation
- Technological devices
- Misbehaviour and criminality
- Other and unspecified lifestyle information
Socio-demographic and economic characteristics
Lifestyle and behaviours
Birth, pregnancy and reproductive health history
Perception of health, quality of life, development and functional limitations
Diseases
Symptoms and signs
Medication and supplements
Non-pharmacological interventions
Health and community care services utilization
Physical measures and assessments
Laboratory measures
Cognition, personality and psychological measures and assessments
Life events, life plans, beliefs and values
Preschool, school and work life
Social environment and relationships
Physical environment
Administrative information
Cognitive functioning
Personality
Psychological distress and emotions
Life events
Life course development
Nutrition
Sleep