Individual Study / C19-IIRLTF

COVID-19 Infection and Immunity in Residents of Long-term Care Facilities
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COVID-19 Infection and Immunity in Residents of Long-term Care Facilities

C19-IIRLTF logo
Networks -
Datasets -
Variables -
Start Year
2021
End Year
2022
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Investigators Contacts
  • Dr. Dawn Bowdish
    McMaster University
  • Dr. Andrew Costa
    McMaster University
  • Dr. Dawn Bowdish
    McMaster University
  • Dr. Andrew Costa
    McMaster University
  • Tara Kajaks
    McMaster University

Design

Study design
Cohort
Follow Up
Residents were followed at the following timepoints, where applicable based on their time of recruitment: at the time of the first dose of the COVID vaccine, at the time of the second dose and 3 weeks, 3 months, 6 months, 9 and 12 months after the second dose. For those who obtained a 3rd dose of the vaccine, follow-up once vaccinated was at 3 weeks, 3 months, and 6 months post 3rd dose. Staff, essential visitors, and residents were followed up every week or at each visit for saliva surveillance testing between date of recruitment and October 2021.

Recruitment

Recruitment Target
  • Individuals

Number of Participants

Number of Participants
6,500
Number of Participants with Biological Samples

Access

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other
Yes
No
Not applicable
Don't know

Timeline

Populations

Selection Criteria
Newborns
Twins
Countries
  • Canada
Territory
Ethnic Origin
Health Status

Recruitment

Sources of recruitment
  • Specific population
Specific Population
  • Other specific population : Long-term care home and retirement home residents
Supplementary Information
Research coordinators from within the partner homes approach residents to invite them to participate in the study.

Number of Participants

Number of Participants
1,003
Number of Participants with Biological Samples
1,003
Supplementary Information about selection criteria
Long-term care residents: 715 Retirement home residents: 288
Data Collection Events
# Name Description Start End
0 C19-IIRLTF - Residents - Baseline Demographic data (age, sex, vaccination dates, vaccination type) was collected at study enrollment and updated as needed. A drop of blood from the fingertip was collected when enrolled and a ... 2021-01 2021-12
1 C19-IIRLTF - Residents - Vaccine 1st dose A drop of blood from the fingertip was collected. 2021-01
2 C19-IIRLTF - Residents - Vaccine 2nd dose A drop of blood from the fingertip was collected. 2021-02
3 C19-IIRLTF - Residents - 3 weeks post 2nd dose A drop of blood from the fingertip was collected. 2021-03
4 C19-IIRLTF - Residents - 5 months post 2nd dose A drop of blood from the fingertip was collected. 2021-07
5 C19-IIRLTF - Residents - 3 weeks post 3rd dose A drop of blood from the fingertip was collected. 2021-08
6 C19-IIRLTF - Residents - Vaccine 3rd dose A drop of blood from the fingertip was collected. 2021-07
7 C19-IIRLTF - Residents - 3 months post 3rd dose A drop of blood from the fingertip was collected and a blood sample was taken. 2021-10
8 C19-IIRLTF - Residents - 6 months post 3rd dose A drop of blood from the fingertip was collected and a blood sample was taken. 2022-01
9 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-01 2021-01
10 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-01 2021-01
11 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-01 2021-01
12 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-01 2021-01
13 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-02 2021-02
14 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-02 2021-02
15 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-02 2021-02
16 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-02 2021-02
17 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-03 2021-03
18 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-03 2021-03
19 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-03 2021-03
20 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-03 2021-03
21 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-04 2021-04
22 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-04 2021-04
23 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-04 2021-04
24 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-04 2021-04
25 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-05 2021-05
26 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-05 2021-05
27 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-05 2021-05
28 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-05 2021-05
29 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-06 2021-06
30 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-06 2021-06
31 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-06 2021-06
32 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-06 2021-06
33 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-07 2021-07
34 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-07 2021-07
35 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-07 2021-07
36 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-07 2021-07
37 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-08 2021-08
38 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-08 2021-08
39 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-08 2021-08
40 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-08 2021-08
41 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-09 2021-09
42 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-09 2021-09
43 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-09 2021-09
44 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-09 2021-09
45 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-10 2021-10
46 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-10 2021-10
47 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-10 2021-10
48 C19-IIRLTF - Residents - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-10 2021-10
Selection Criteria
Newborns
Twins
Countries
  • Canada
Territory
Ethnic Origin
Health Status

Recruitment

Sources of recruitment
  • Specific population
Specific Population
  • Other specific population : essential caregivers in long term care homes
Supplementary Information
Research coordinators from within the partner LTC homes are approaching LTC full- and part-time staff and designated essential caregivers.

Number of Participants

Number of Participants
126
Number of Participants with Biological Samples
126
Data Collection Events
# Name Description Start End
0 C19-IIRLTF - Essential caregivers - Baseline Information was collected from a questionnaire about participant characteristics (e.g. age, sex, ethnicity, household demographics, education level, employment, health conditions, COVID-19 testing ... 2021-01 2021-10
1 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-01 2021-01
2 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-01 2021-01
3 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-01 2021-01
4 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-01 2021-01
5 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-02 2021-02
6 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-02 2021-02
7 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-02 2021-02
8 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-02 2021-02
9 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-03 2021-03
10 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-03 2021-03
11 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-03 2021-03
12 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-03 2021-03
13 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-04 2021-04
14 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-04 2021-04
15 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-04 2021-04
16 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-04 2021-04
17 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-05 2021-05
18 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-05 2021-05
19 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-05 2021-05
20 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-05 2021-05
21 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-06 2021-06
22 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-06 2021-06
23 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-06 2021-06
24 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-06 2021-06
25 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-07 2021-07
26 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-07 2021-07
27 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-07 2021-07
28 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-07 2021-07
29 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-08 2021-08
30 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-08 2021-08
31 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-08 2021-08
32 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-08 2021-08
33 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-09 2021-09
34 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-09 2021-09
35 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-09 2021-09
36 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-09 2021-09
37 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-10 2021-10
38 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-10 2021-10
39 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-10 2021-10
40 C19-IIRLTF - Essential caregivers - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-10 2021-10
Selection Criteria
Newborns
Twins
Countries
  • Canada
Territory
Ethnic Origin
Health Status

Recruitment

Sources of recruitment
  • Specific population
Specific Population
  • Other specific population : staff from long-term care homes
Supplementary Information
Research coordinators from within the partner LTC homes are approaching LTC residents' substitute decision makers as required, to invite them to participate in the study.

Number of Participants

Number of Participants
138
Number of Participants with Biological Samples
138
Data Collection Events
# Name Description Start End
0 C19-IIRLTF - Staff - Baseline Information was collected from a questionnaire about participant characteristics (e.g. age, sex, ethnicity, household demographics, education level, employment, health conditions, COVID-19 testing ... 2021-01 2021-10
1 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-01 2021-01
2 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-01 2021-01
3 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-01 2021-01
4 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-01 2021-01
5 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-02 2021-02
6 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-02 2021-02
7 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-02 2021-02
8 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-02 2021-02
9 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-03 2021-03
10 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-03 2021-03
11 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-03 2021-03
12 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-03 2021-03
13 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-04 2021-04
14 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-04 2021-04
15 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-04 2021-04
16 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-04 2021-04
17 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-05 2021-05
18 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-05 2021-05
19 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-05 2021-05
20 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-05 2021-05
21 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-06 2021-06
22 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-06 2021-06
23 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-06 2021-06
24 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-06 2021-06
25 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-07 2021-07
26 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-07 2021-07
27 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-07 2021-07
28 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-07 2021-07
29 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-08 2021-08
30 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-08 2021-08
31 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-08 2021-08
32 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-08 2021-08
33 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-09 2021-09
34 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-09 2021-09
35 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-09 2021-09
36 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-09 2021-09
37 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-10 2021-10
38 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-10 2021-10
39 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-10 2021-10
40 C19-IIRLTF - Staff - Weekly saliva One saliva sample or swab was collected every week over the duration of the study. 2021-10 2021-10

Classifications

Socio-demographic and economic characteristics
Lifestyle and behaviours
Birth, pregnancy and reproductive health history
Perception of health, quality of life, development and functional limitations
Diseases
Symptoms and signs
Medication and supplements
Non-pharmacological interventions
Health and community care services utilization
Death
Physical measures and assessments
Laboratory measures
Cognition, personality and psychological measures and assessments
Life events, life plans, beliefs and values
Preschool, school and work life
Social environment and relationships
Physical environment
Administrative information
Perception of health
Quality of life
Life course development
Functional limitations
Other perception of health, quality of life and functional limitation-related information

Socio-demographic and economic characteristics

Age/birthdate
Sex/gender
Family and household structure
Ethnicity, race and religion

Lifestyle and behaviours

Physical activity
Leisure activities
Other and unspecified lifestyle information

Perception of health, quality of life, development and functional limitations

Perception of health
Quality of life
Functional limitations

Diseases

Certain infectious and parasitic diseases (A00-B99)
Neoplasms (C00-D48)
Endocrine, nutritional and metabolic diseases (E00-E90)
Mental and behavioural disorders (F00-F99)
Diseases of the nervous system (G00-G99)
Diseases of the eye and adnexa (H00-H59)
Diseases of the circulatory system (I00-I99)
Diseases of the respiratory system (J00-J99)
Diseases of the digestive system (K00-K93)
Diseases of the musculoskeletal system and connective tissue (M00-M99)
Diseases of the genitourinary system (N00-N99)
Diseases without precise specification or falling into multiple categories

Symptoms and signs

Symptoms and signs involving cognition, perception, emotional state and behaviour (R40-R46)
Symptoms related to multiple categories

Medication and supplements

Medication and supplement intake
Posology and protocol of administration

Non-pharmacological interventions

Surgical interventions
Other and unspecified non-pharmacological interventions

Health and community care services utilization

Visits to health professionals
Hospitalizations

Physical measures and assessments

Anthropometry

Laboratory measures

Virology

Physical environment

Housing characteristics
Biological exposure

Administrative information

Identifiers
Date and time-related information

Functional limitations

Activities of Daily Living
Instrumental Activities of Daily Living