Accelerating SARS-CoV-2 SEroprevalence SurveyS through Dried Blood Spots
Networks
-
Datasets
-
Variables
-
The specific aims of the study are to:
* Estimate the prevalence of antibodies against SARS-CoV-2 virus among people in British Columbia (BC) Provincial Correctional Centres.
* Investigate people’s willingness and barriers to getting assessed for antibodies against SARS-CoV-2 virus among people in BC Provincial Correctional Centres.
* Determine if Dried Blood Spots (DBS) samples and venepuncture samples are equivalent for measuring the presence of antibodies against SARS-CoV-2 virus in a real world setting such as correctional centres.
- Start Year
- 2020
- End Year
- 2021
| Investigators | Contacts |
|---|---|
|
|
Design
- Study design
- Cross-sectional
- Follow Up
- At baseline, asymptomatic and symptomatic for COVID-19 participants are tested with antibody assays (serology) and Nucleic Acid Testing (NAT). Participants are followed up depending on whether they were symptomatic or asymptomatic and the result of their test(s). If they were symptomatic and both tests (NAT and serology) were positive or one test (NAT) was positive and the other (serology) was negative, they were followed up 3 weeks after baseline. If they were asymptomatic and their test (serology) was positive, they were followed up immediately after baseline.
- Supplementary Information
Recruitment
- Recruitment Target
-
- Individuals
Number of Participants
- Number of Participants
- 836
- Number of Participants with Biological Samples
- 836
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
Timeline
Populations
The population is composed of people who are at least 18 years of age, incarcerated in British Columbia (BC) Provincial Correctional Centres (sentenced and remand) or staff who work in BC Provincial Correctional Centres and screened as asymptomatic for COVID-19.
Selection Criteria
- Minimum age
-
18
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Ethnic Origin
-
- Health Status
-
- Other Criteria
- Are currently incarcerated provincially in British Columbia or currently working in a British Columbia Provincial Correctional Centre
Recruitment
- Sources of recruitment
-
- Specific population
- Specific Population
-
- Other specific population : Incarcerated in BC Provincial Correctional Centres and staff who work in BC Provincial Correctional Centres
- Supplementary Information
-
The study will use stratified random sampling. Recruitment for this study will be facilitated by distributing information about the study to ward reps in every correctional centre, so they are able to advise residents on their ward about the study. Information will also be distributed to Corrections staff through usual staff communication channels (email distribution lists and staff notice boards, etc.) for both Corrections Officers and Correctional Health Services (CHS) staff.
Number of Participants
- Number of Participants
- Number of Participants with Biological Samples
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
ASSESS-DBS - Asymptomatic - Baseline
|
Clinical and demographic information are collected in questionnaire. Specimen are collected using the Dried blood spot and a venous blood sample to perform a SARS-CoV-2 serology testing. | 2021 | 2021 |
| 2 |
ASSESS-DBS - Asymptomatic - Follow-up
|
Clinical and demographic information are collected in questionnaire. Nasopharyngeal swab sample or saline gargle specimen are collected for Nucleic Acid Testing. | 2021 | 2021 |
The population is composed of people who are at least 18 years of age, incarcerated in British Columbia (BC) Provincial Correctional Centres (sentenced and remand) or staff who work in BC Provincial Correctional Centres and screened as symptomatic for COVID-19.
Selection Criteria
- Minimum age
-
18
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Ethnic Origin
-
- Health Status
-
- Other Criteria
- Are currently incarcerated provincially in British Columbia or currently working in a British Columbia Provincial Correctional Centre
Recruitment
- Sources of recruitment
-
- Specific population
- Specific Population
-
- Other specific population : Incarcerated in BC Provincial Correctional Centres and staff who work in BC Provincial Correctional Centres
- Supplementary Information
-
The study will use stratified random sampling. Recruitment for this study will be facilitated by distributing information about the study to ward reps in every correctional centre, so they are able to advise residents on their ward about the study. Information will also be distributed to Corrections staff through usual staff communication channels (email distribution lists and staff notice boards, etc.) for both Corrections Officers and Correctional Health Services (CHS) staff.
Number of Participants
- Number of Participants
- Number of Participants with Biological Samples
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
ASSESS-DBS - Symptomatic - Baseline
|
Clinical and demographic information are collected in questionnaire. Specimen are collected using the Dried blood spot and a venous blood sample. Nasopharyngeal swab or saline gargle specimen are ... | 2021 | 2021 |
| 1 |
ASSESS-DBS - Symptomatic - Follow-up
|
Clinical and demographic information are collected in questionnaire. Specimen are collected using the Dried blood spot and a venous blood sample. A saline gargle specimen is collected as well for ... | 2021 | 2021 |
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
Socio-demographic and economic characteristics
Age/birthdate
Sex/gender
Education
Residence
Ethnicity, race and religion
Labour force and retirement
Lifestyle and behaviours
Tobacco
Drugs
Leisure activities
Perception of health, quality of life, development and functional limitations
Quality of life
Diseases
Certain infectious and parasitic diseases (A00-B99)
Neoplasms (C00-D48)
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Endocrine, nutritional and metabolic diseases (E00-E90)
Diseases of the nervous system (G00-G99)
Diseases of the circulatory system (I00-I99)
Diseases of the respiratory system (J00-J99)
Diseases of the digestive system (K00-K93)
Diseases of the genitourinary system (N00-N99)
Symptoms and signs
Symptoms and signs involving the circulatory and respiratory systems (R00-R09)
Symptoms and signs involving the digestive system and abdomen (R10-R19)
Symptoms and signs involving nervous and musculoskeletal systems (R25-R29)
Symptoms and signs involving cognition, perception, emotional state and behaviour (R40-R46)
General symptoms and signs (R50-R69)
Symptoms related to multiple categories
Medication and supplements
Medication and supplement intake
Non-pharmacological interventions
Laboratory diagnosis interventions
Other and unspecified non-pharmacological interventions
Health and community care services utilization
Hospitalizations
Laboratory measures
Virology
Cognition, personality and psychological measures and assessments
Personality
Life events, life plans, beliefs and values
Life events
Beliefs and values
Administrative information
Identifiers
Date and time-related information