Alberta Pregnancy Outcomes and Nutrition
- Examine the associations between maternal prenatal nutritional intake and status and mothers' and children's mental health and children's neurodevelopment;
- Investigate the risk factors associated with maternal and paternal perinatal mood, and the impact of maternal and paternal perinatal mood on pregnancy and birth outcomes, as well as children's mental health and neurodevelopment;
- Establish a DNA biobank that could be used to examine the influence of genomics on children's mental health and neurodevelopment.
- Start Year
- 2009
- Supplementary Information
Visit APrON
| Investigators | Contacts |
|---|---|
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Design
- Study design
- Cohort
- Follow Up
- Women had their first visit in either their first or second trimester prior to 27 weeks gestation. Women were seen again in the research lab in each remaining trimester and at 3 months postpartum with their babies. Questionnaires were given to mothers approximately 6, 12, 24 and 36 months after delivery.
- Supplementary Information
Marker Paper
Kaplan BJ, Giesbrecht GF, Leung BM, Field CJ, Dewey D, Bell RC, Manca DP, O'Beirne M, Johnston DW, Pop VJ, Singhal N, Gagnon L, Bernier FP, Eliasziw M, McCargar LJ, Kooistra L, Farmer A, Cantell M, Goonewardene L, Casey LM, Letourneau N, Martin JW; APrON Study Team. The Alberta Pregnancy Outcomes and Nutrition (APrON) cohort study: rationale and methods. Maternal and Child Nutrition. 2014 Jan;10(1):44-60.
PUBMED 22805165
Recruitment
- Recruitment Target
-
- Families
Number of Participants
- Number of Participants
- 5,841
- Number of Participants with Biological Samples
- 5,175
- Supplementary Information
-
Mothers: 2189 participants
Partners: 1483 participants
Children: 2169 participants
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Availability of access information
On the study website : https://apronstudy.ca/
By contacting the study representative
Sector of research
| Possible Access to Data | Possible Access to Biosamples | |
|---|---|---|
| Investigators from the public sector | ||
| Investigators from the private sector | ||
| Investigators from not-for-profit organization |
Transfer
| Possible Access to Data | Possible Access to Biosamples | |
|---|---|---|
| Can leave the study facility | ||
| Can leave the country |
In order for requesting researchers to receive APrON data, all data requests must be reviewed and approved by a Principal Investigator; all data requests must be made in agreement with the researcher’s supervisor (if applicable); all data must be anonymized by the study team; and all researchers must sign a confidentiality agreement to not share the data with anyone else who was not approved in the request.
Cost
| Possible Access to Data | Variable Cost |
| Possible Access to Biosamples | Variable Cost |
We charge the amount of time it takes our staff to fill the request.
Cost reduction for co-analyses
| Possible Access to Data | |
| Possible Access to Biosamples |
Timeline
Populations
Selection Criteria
- Sex
-
Women
- Minimum age
-
16
- Pregnant Women
-
- First trimester
- Second trimester
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Metropolitan areas of Calgary and Edmonton in Alberta
- Ethnic Origin
-
- Health Status
-
- Other Criteria
- Gestational age of less than 27 weeks
Recruitment
- Sources of recruitment
-
- General population
- Specific population
- General Population
-
- Volunteer enrolment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Calgary recruitment included stationing research assistants in waiting rooms of high-volume maternity care and ultrasound clinics. Edmonton recruitment was organized through a collaborative process with the Women and Children’s Health Research Institute at the University of Alberta, distributing information across the city’s many clinics. Other recruitment strategies used in both cities included posters and media advertising.
Number of Participants
- Number of Participants
- 2,189
- Number of Participants with Biological Samples
- 2,041
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
APrON - Mothers - First trimester
|
The first pregnancy trimester (1-13 weeks) only assesses women recruited before 13 weeks of gestation. A questionnaire was used to assess pregnancy information, current physical ... |
2009-01 | 2012-06 |
| 1 |
APrON - Mothers - Second trimester
|
A questionnaire was used to assess pregnancy information, physical activity within 12 months preceding pregnancy, current physical activity, current mental health, current medical conditions, ... |
2009-05 | 2012-09 |
| 2 |
APrON - Mothers - Third trimester
|
A questionnaire was used to assess pregnancy information, physical activity, current mental health, current medical conditions, social support, life events, medication use, recreational drug ... |
2009-07 | 2012-11 |
| 3 |
APrON - Mothers - Birth
|
Information about delivery and birth outcomes was abstracted from hospital or midwife records. Labor and delivery information reviewed includes duration of labor, pain management, induction, ... |
2009-08 | 2013-02 |
| 4 |
APrON - Mothers - 12 weeks postpartum
|
A questionnaire inquired about details that could change from the maternal questionnaires that were administered during pregnancy (i.e. current mental health, medication use, social support, ... |
2009-11 | 2013-05 |
| 5 |
APrON - Mothers - 24 weeks postpartum
|
A questionnaire inquired about details that could change from questionnaire completed at 12 weeks postpartum (i.e. current mental health, medication use, social support, physical activity, and ... |
2010-02 | 2013-11 |
| 6 |
APrON - Mothers - 12 months postpartum
|
A questionnaire inquired about details that could change from the questionnaire completed at 24 weeks postpartum (i.e. current mental health, medication use, social support, physical activity, ... |
2010-09 | 2014-06 |
| 7 |
APrON - Mothers - 24 months postpartum
|
A questionnaire inquired about details that could change from the questionnaire completed at 12 months postpartum (i.e. current mental health, medication use, social support, physical activity, ... |
2011-08 | 2015-02 |
| 8 |
APrON - Mothers - 3 years postpartum
|
A questionnaire inquired about details that could change from the questionnaire completed at 24 months postpartum (i.e. current mental health, medication use, social support, physical ... |
2012-09 | 2016-05 |
| 9 |
APrON - Mothers - 5 years postpartum
|
A questionnaire inquired about details that could change from the questionnaire completed at 3 years postpartum (i.e. current mental health, medication use, social support, physical activity, ... |
2014-08 | 2018-05 |
Selection Criteria
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Metropolitan areas of Calgary and Edmonton in Alberta
- Ethnic Origin
-
- Health Status
-
Recruitment
- Sources of recruitment
-
- Specific population
- Specific Population
-
- Other specific population : Partners of the pregnant women already recruited.
Number of Participants
- Number of Participants
- 1,483
- Number of Participants with Biological Samples
- 1,343
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
APrON - Partners - Second trimester
|
For the paternal questionnaire, partners answered questions pertaining to sociodemographic information, a 24 hour food recall for the day prior to the visit, a 3 hour food recall for the 3 ... |
2009-04 | 2012-12 |
| 1 |
APrON - Partners - 12 weeks postpartum
|
A questionnaire inquired about details that could change from the questionnaire that was administered during pregnancy (i.e. current mental health, medication use, social support, physical ... |
2009-11 | 2013-05 |
| 2 |
APrON - Partners - 5 years postpartum
|
A questionnaire inquired about details that could change from the questionnaire completed at 12 weeks postpartum (i.e. current mental health, medication use, social support, physical activity, ... |
2014-08 | 2018-05 |
Selection Criteria
- Newborns
- Twins
- Countries
-
- Canada
- Territory
- Metropolitan areas of Calgary and Edmonton in Alberta
- Ethnic Origin
-
- Health Status
-
Recruitment
- Sources of recruitment
-
- Specific population
- Specific Population
-
- Other specific population : Newborn children of the women enrolled in the study.
Number of Participants
- Number of Participants
- 2,169
- Number of Participants with Biological Samples
- 1,791
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
APrON - Children - Birth
|
Information about delivery and birth outcomes was abstracted from hospital or midwife records. Newborn information collected includes newborn health, birth weight, gestational age at birth, ... |
2009-08 | 2013-05 |
| 1 |
APrON - Children - 12 weeks postpartum
|
A parent-report of infant health and behavior, infant feeding practices, and breastfeeding was collected for the infant questionnaire. Mothers were also asked about their employment patterns ... |
2009-11 | 2013-05 |
| 2 |
APrON - Children - 24 weeks postpartum
|
A parent-report of infant health and behavior, infant feeding practices, and breastfeeding was collected for the infant questionnaire. Mothers were also asked about their employment patterns ... |
2010-02 | 2013-08 |
| 3 |
APrON - Children - 12 months postpartum
|
A parent-report of infant health and behavior, infant feeding practices, and breastfeeding was collected for the infant questionnaire. Mothers were also asked about their employment patterns ... |
2010-09 | 2014-02 |
| 4 |
APrON - Children - 24 months postpartum
|
A parent-report of infant health and behavior, infant feeding practices, and breastfeeding was collected for the child questionnaire. Mothers were also asked about their employment patterns and ... |
2011-08 | 2015-02 |
| 5 |
APrON - Children - 3 years postpartum
|
A parent-report of infant health, behavior, and feeding practices was collected for the child questionnaire. Mothers were also asked about their employment patterns and utilization of child ... |
2012-09 | 2016-05 |
| 6 |
APrON - Children - 5 years postpartum
|
A parent-report of infant health, behavior, and feeding practices was collected for the child questionnaire. Mothers were also asked about their employment patterns and utilization of child ... |
2014-08 | 2018-05 |
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
- Cognitive functioning
- Personality
- Psychological distress and emotions
- Other psychological measures and assessments
- Life events
- Beliefs and values
- Perception of health
- Quality of life
- Life course development
- Functional limitations
- Other perception of health, quality of life and functional limitation-related information
- Tobacco
- Alcohol
- Drugs
- Nutrition
- Breastfeeding
- Physical activity
- Sleep
- Sexual behaviours and orientation
- Technological devices
- Misbehaviour and criminality
- Other and unspecified lifestyle information
Socio-demographic and economic characteristics
Lifestyle and behaviours
Birth, pregnancy and reproductive health history
Perception of health, quality of life, development and functional limitations
Diseases
Symptoms and signs
Medication and supplements
Non-pharmacological interventions
Health and community care services utilization
Physical measures and assessments
Cognition, personality and psychological measures and assessments
Life events, life plans, beliefs and values
Preschool, school and work life
Social environment and relationships
Physical environment
Administrative information
Cognitive functioning
Personality
Psychological distress and emotions
Other psychological measures and assessments
Life events
Beliefs and values
Quality of life
Life course development
Nutrition
Physical activity
Sleep