Maelstrom Research Staging

Avon Longitudinal Study of Parents and Children

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Datasets -

Variables -

Start Year: 1990

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Investigators	Contacts
Prof. Paul Burton Newcastle University Paul Burton Title Prof. Name Paul Burton Email paul.burton@newcastle.ac.uk Institution Newcastle University Department Institute of Health and Society Address Newcastle upon Tyne United Kingdom Prof. George Smith University of Bristol George Smith Title Prof. Name George Smith Email kz.davey-smith@bristol.ac.uk Phone +44 (0) 117 3310095 Institution University of Bristol Department School of Social and Community Medicine Address Bristol United Kingdom Dr Nicholas Timpson University of Bristol Nicholas Timpson Title Dr Name Nicholas Timpson Email n.j.timpson@bristol.ac.uk Phone +44 (0) 117 3310131 Institution University of Bristol Department Department of Epidemiology Address Bristol United Kingdom	Lynn Molloy University of Bristol Lynn Molloy Name Lynn Molloy Email lynn.molloy@bristol.ac.uk Phone +44 (0) 117 3310080 Institution University of Bristol Department School of Social and Community Medicine Address Bristol United Kingdom

Investigators

Contacts

Prof. Paul Burton
Newcastle University

Paul Burton

Title

Prof.

Name

Paul Burton

Email

paul.burton@newcastle.ac.uk

Institution

Newcastle University

Department

Institute of Health and Society

Address

Newcastle upon Tyne United Kingdom
Prof. George Smith
University of Bristol

George Smith

Title

Prof.

Name

George Smith

Email

kz.davey-smith@bristol.ac.uk

Phone

+44 (0) 117 3310095

Institution

University of Bristol

Department

School of Social and Community Medicine

Address

Bristol United Kingdom
Dr Nicholas Timpson
University of Bristol

Nicholas Timpson

Title

Dr

Name

Nicholas Timpson

Email

n.j.timpson@bristol.ac.uk

Phone

+44 (0) 117 3310131

Institution

University of Bristol

Department

Department of Epidemiology

Address

Bristol United Kingdom

Lynn Molloy
University of Bristol

Lynn Molloy

Name

Lynn Molloy

Email

lynn.molloy@bristol.ac.uk

Phone

+44 (0) 117 3310080

Institution

University of Bristol

Department

School of Social and Community Medicine

Address

Bristol United Kingdom

Design

Study design

Cohort

Follow Up

During the index pregnancy, most women were sent 3 questionnaires. Since then, over a period of some 25 years, women have been sent 22 additional questionnaires that refer to their own health and well-being. Since 2008, women have attended four focus clinical ssessments

Assessments of the children have been administered frequently, with 64 data collection time points between birth and 24 years of age. These include 34 child-completed questionnaires, 20 focus clinical assessments and 23 questionnaires about the child completed by the mother or other main caregiver.

Partners have been sent 17 questionnaires and have attended 1 focus clinic assessment.

Siblings and grandparents have been recruited.

Supplementary Information

Marker Paper

Boyd A., Golding J., Macleod J., Lawlor D.A., Fraser A., Henderson J., Molloy L., Ness A., Ring S., Davey Smith G. Cohort Profile: The ‘Children of the 90s’—the index offspring of the Avon Longitudinal Study of Parents and Children. International Journal of Epidemiology 2012;1-17

PUBMED 22507743

Recruitment

Recruitment Target

Families

Number of Participants

Number of Participants

42,710

Number of Participants with Biological Samples

22,000 (No Limit)

Supplementary Information

ALSPAC recruited 14,541 pregnant women resident in Avon, UK with expected dates of delivery 1st April 1991 to 31st December 1992. 14,541 is the initial number of pregnancies for which the mother enrolled in the ALSPAC study and had either returned at least one questionnaire or attended a “Children in Focus” clinic by 19/07/99. Of these initial pregnancies, there was a total of 14,676 fetuses, resulting in 14,062 live births and 13,988 children who were alive at 1 year of age.

When the oldest children were approximately 7 years of age, an attempt was made to bolster the initial sample with eligible cases who had failed to join the study originally. As a result, when considering variables collected from the age of seven onwards (and potentially abstracted from obstetric notes) there are data available for more than the 14,541 pregnancies mentioned above.

The number of new pregnancies not in the initial sample (known as Phase I enrolment) that are currently represented on the built files and reflecting enrolment status at the age of 18 is 706 (452 and 254 recruited during Phases II and III respectively), resulting in an additional 713 children being enrolled. The phases of enrolment are described in more detail in the cohort profile paper which should be used for referencing purposes: <http://ije.oxfordjournals.org/content/early/2012/04/14/ije.dys064.full.pdf+html>.

The total sample size for analyses using any data collected after the age of seven is therefore 15,247 pregnancies, resulting in 15,458 fetuses. Of this total sample of 15,458 fetuses, 14,775 were live births and 14,701 were alive at 1 year of age.

A 10% sample of the ALSPAC cohort, known as the Children in Focus (CiF) group, attended clinics at the University of Bristol at various time intervals between 4 to 61 months of age. The CiF group were chosen at random from the last 6 months of ALSPAC births (1432 families attended at least one clinic). Excluded were those mothers who had moved out of the area or were lost to follow-up, and those partaking in another study of infant development in Avon.

Access

General Information

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other

Yes

Not applicable

Don't know

Timeline

Populations

Selection Criteria

Sex

Women

Pregnant Women

First trimester
Second trimester
Third trimester

Newborns

Twins

Countries

United Kingdom

Territory

Old administrative county of Avon, South West England.

Ethnic Origin

Health Status

Recruitment

Sources of recruitment

General population
Specific population

General Population

Volunteer enrolment

Specific Population

Clinic patients

Supplementary Information

ALSPAC attempted to make contact with eligible women through media information encouraging study contact and recruitment staff visiting community locations. In parallel, routine antenatal and maternity health services were used to promote the study and distribute an ‘expression of interest’ card. Through returning this card, women were able to request further information on the study or to decline participation. Completed cards contained sufficient detail to allow ALSPAC staff to determine eligibility.

Posters were printed for display in a variety of different places - including chemist shops, libraries, mother and toddler groups, and pre-school playgroups, general practitioner waiting-rooms, antenatal clinics and any other area where a mother in early pregnancy was likely to be. In addition, there was considerable local and national coverage in the press, radio and television.

Number of Participants

Number of Participants: 14,541
Number of Participants with Biological Samples: 10,000 (No Limit)

Data Collection Events

#	Name	Description	Start	End
0	ALSPAC - Mothers - Biosample collection 1990 to 1992 ALSPAC - Mothers - Biosample collection 1990 to 1992 Start Date 1990-07 End Date 1992-03 Data sources Biosamples Data sources - Biosamples Blood Urine Files No files could be found.	A blood and urine sample were collected.	1990-07	1992-03
1	ALSPAC - Mothers - 8 to 42 weeks gestation ALSPAC - Mothers - 8 to 42 weeks gestation Start Date 1990-09 End Date 1992-10 Data sources Questionnaires Physical measures Administrative databases Other : Obstetric clinical records Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Using a questionnaire, information was collected about environment; where participant lives and works, and about ...	1990-09	1992-10
2	ALSPAC - Mothers - 18 weeks gestation ALSPAC - Mothers - 18 weeks gestation Start Date 1990-11 End Date 1992-09 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Using a questionnaire, information was collected about feelings during pregnancy. In addition, information was ...	1990-11	1992-09
3	ALSPAC - Mothers - 12 weeks gestation ALSPAC - Mothers - 12 weeks gestation Start Date 1990-11 End Date 1993-08 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Using a questionnaire, information was collected about health, partner, home, childhood and beliefs and attitudes. ...	1990-11	1993-08
4	ALSPAC - Mothers - 32 weeks gestation ALSPAC - Mothers - 32 weeks gestation Start Date 1991-03 End Date 1993-01 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Using a questionnaire, information was collected about feelings, background, plans and preparations for the baby. In ...	1991-03	1993-01
5	ALSPAC - Mothers - 8 weeks ALSPAC - Mothers - 8 weeks Start Date 1991-05 End Date 1993-04 Data sources Questionnaires Administrative databases Other : Obstetric medical records Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Using a questionnaire information was collected about feelings, amount of sleep, and reaction to the actual birth of baby. In addition, information was collected about general physical ...	1991-05	1993-04
6	ALSPAC - Mothers - 8 months ALSPAC - Mothers - 8 months Start Date 1992-04 End Date 1993-10 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Using a questionnaire information was collected about lifestyle. In addition, information was collected about general physical health, obstetric health, mental health, diet and nutrition, ...	1992-04	1993-10
7	ALSPAC - Mothers - 21 months ALSPAC - Mothers - 21 months Start Date 1992-09 End Date 1994-11 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Using a questionnaire information was collected about problems toddlers and their parents have. In addition, information was collected about general physical health, obstetric health, mental ...	1992-09	1994-11
8	ALSPAC - Mothers - 33 months ALSPAC - Mothers - 33 months Start Date 1993-10 End Date 1995-11 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaire collected information about parents' problems. In addition, information was collected about general ...	1993-10	1995-11
9	ALSPAC - Mothers - Biosample collection 1993 ALSPAC - Mothers - Biosample collection 1993 Start Date 1993-11 End Date 1993-11 Data sources Biosamples Data sources - Biosamples Hair Nail Files No files could be found.	A hair and nail sample were collected.	1993-11	1993-11
10	ALSPAC - Mothers - 47 months ALSPAC - Mothers - 47 months Start Date 1994-11 End Date 1997-01 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaire collected information about problems parents have. In addition, information was collected about ...	1994-11	1997-01
11	ALSPAC - Mothers - 61 months ALSPAC - Mothers - 61 months Start Date 1996-01 End Date 1998-03 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaire collected information about health and other problems. In addition, information was collected about ...	1996-01	1998-03
12	ALSPAC - Mothers - 73 months ALSPAC - Mothers - 73 months Start Date 1997-02 End Date 1999-03 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaire collected information about lifestyle. In addition, information was collected about general physical ...	1997-02	1999-03
13	ALSPAC - Mothers - 85 months ALSPAC - Mothers - 85 months Start Date 1998-08 End Date 2000-03 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaire collected information about the mother and the home. In addition, information was collected about ...	1998-08	2000-03
14	ALSPAC - Mothers - 97 months ALSPAC - Mothers - 97 months Start Date 1999-09 End Date 2001-05 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaire collected information about the other and the family. In addition, information was collected about ...	1999-09	2001-05
15	ALSPAC - Mothers - 110 months ALSPAC - Mothers - 110 months Start Date 2000-10 End Date 2002-04 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaire collected information about having a 9-year-old. In addition, information was collected about general ...	2000-10	2002-04
16	ALSPAC - Mothers - 122 months ALSPAC - Mothers - 122 months Start Date 2001-08 End Date 2003-04 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaire collected information about the participant and their surroundings. In addition, information was ...	2001-08	2003-04
17	ALSPAC - Mothers - 134 months ALSPAC - Mothers - 134 months Start Date 2002-07 End Date 2004-05 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaire collected information about problems, as well as some features of lifestyle. In addition, information ...	2002-07	2004-05
18	ALSPAC - Mothers - 145 months ALSPAC - Mothers - 145 months Start Date 2003-05 End Date 2005-05 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaire collected information about problems and lifestyle. Education was also assessed. In addition, ...	2003-05	2005-05
19	ALSPAC - Mothers - Biosample collection 2004 to 2008 ALSPAC - Mothers - Biosample collection 2004 to 2008 Start Date 2004 End Date 2008 Data sources Biosamples Data sources - Biosamples Blood Urine Files No files could be found.	A blood and urine sample were collected.	2004	2008
20	ALSPAC - Mothers - 156 months ALSPAC - Mothers - 156 months Start Date 2004-05 End Date 2004-10 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Information was collected about what types of adult learning have been undertaken, reasons for studying, location ...	2004-05	2004-10
21	ALSPAC - Mothers - Focus on mothers 1 ALSPAC - Mothers - Focus on mothers 1 Start Date 2008-12 End Date 2011-07 Data sources Questionnaires Physical measures Biosamples Data sources - Biosamples Blood Files No files could be found.	Information was collected about menstrual cycle, reproductive health, hormone use and medication use. Anthropometry, blood pressure, and carotid intima media thickness were measured. A ...	2008-12	2011-07
22	ALSPAC - Mothers - 18 years ALSPAC - Mothers - 18 years Start Date 2009-05 End Date 2010-09 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Information was collected using 2 questionnaires. The first questionnaire collected information about home life, ...	2009-05	2010-09
23	ALSPAC - Mothers - Focus on mothers 2 ALSPAC - Mothers - Focus on mothers 2 Start Date 2011-07 End Date 2013-06 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Files No files could be found.	Information was collected about menstrual cycle, reproductive health, hormone use and medication use. Anthropometry, blood pressure, grip strength, allergies, chair rise test and ...	2011-07	2013-06
24	ALSPAC - Mothers - 20 years ALSPAC - Mothers - 20 years Start Date 2011-09 End Date 2012-02 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Information was collected about whether study child is in school or working, friendships and relationships with ...	2011-09	2012-02
25	ALSPAC - Mothers - 22 years ALSPAC - Mothers - 22 years Start Date 2012-09 End Date 2014-12 Data sources Questionnaires Administrative databases Data sources - Administrative databases Health databases Vital statistics databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Information was collected about family and home life, employment and finances, health, reproductive health, sexual ...	2012-09	2014-12
26	ALSPAC - Mothers - Focus on mothers 3 ALSPAC - Mothers - Focus on mothers 3 Start Date 2013-03 End Date 2014-03 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Files No files could be found.	Information was collected about menstrual cycle, reproductive health, hormone use and medication use. Anthropometry, blood pressure, grip strength, allergies, acceleration forces ...	2013-03	2014-03
27	ALSPAC - Mothers - Focus on mothers 4 ALSPAC - Mothers - Focus on mothers 4 Start Date 2014-04 End Date 2015-03 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Files No files could be found.	Information was collected about menstrual cycle, reproductive health, hormone use and medication use. Anthropometry, BCG injection and scarring, blood pressure, carotid intima media ...	2014-04	2015-03

Selection Criteria

Newborns

Twins

Countries

United Kingdom

Territory

Old administrative county of Avon.

Ethnic Origin

Health Status

Other Criteria

Recruitment

Sources of recruitment

Specific population

Specific Population

Other specific population :
Mothers’ partners or fathers of the children recruited in ALSPAC.

Number of Participants

Number of Participants

10,207

Number of Participants with Biological Samples

1,000

Supplementary Information about selection criteria

Partners of the mothers were invited to complete self completion questionnaires from pregnancy onwards by the mother.

Fathers were then enrolled into the study in their own right - 3000 were enrolled in 2010 and were invited to attend a hands-on clinical assessment and complete further questionnaries.

Data Collection Events

#	Name	Description	Start	End
0	ALSPAC - Partners - 18 weeks gestation ALSPAC - Partners - 18 weeks gestation Start Date 1990-11 End Date 1992-09 Data sources Questionnaires Files No files could be found.	Information was collected about the participant and their feelings at this stage in their partner's pregnancy from the Partner’s Questionnaire. In addition, information was collected about ...	1990-11	1992-09
1	ALSPAC - Partners - 12 weeks gestation ALSPAC - Partners - 12 weeks gestation Start Date 1990-11 End Date 1993-08 Data sources Questionnaires Files No files could be found.	Information was collected about the participant’s health, their partner, their childhood and their beliefs and attitudes from the You and Your Environment Questionnaire. In addition, ...	1990-11	1993-08
2	ALSPAC - Partners - 8 weeks ALSPAC - Partners - 8 weeks Start Date 1991-05 End Date 1993-04 Data sources Questionnaires Files No files could be found.	Information was collected about the participant's state since the birth of the baby (how they felt, whether they got enough sleep and how they reacted to the actual birth) from the Being a ...	1991-05	1993-04
3	ALSPAC - Partners - 8 months ALSPAC - Partners - 8 months Start Date 1992-04 End Date 1993-10 Data sources Questionnaires Files No files could be found.	Information was collected about health and lifestyle once the baby was over 6 months old from the The Baby and Me Questionnaire. In addition, information was collected about general physical ...	1992-04	1993-10
4	ALSPAC - Partners - 21 months ALSPAC - Partners - 21 months Start Date 1992-09 End Date 1994-11 Data sources Questionnaires Files No files could be found.	Information was collected about lifestyle, having and bringing up a toddler, and about yourself from the A Toddler in the House Questionnaire. In addition, information was collected about ...	1992-09	1994-11
5	ALSPAC - Partners - 33 months ALSPAC - Partners - 33 months Start Date 1993-10 End Date 1995-11 Data sources Questionnaires Files No files could be found.	Information was collected about lifestyle, the role in bringing up a child and any problems from the Partner’s Health Events and Feelings Questionnaire. In addition, information was collected ...	1993-10	1995-11
6	ALSPAC - Partners - Biosample collection 1993 ALSPAC - Partners - Biosample collection 1993 Start Date 1993-11 End Date 1993-11 Data sources Biosamples Data sources - Biosamples Hair Nail Files No files could be found.	A hair and nails sample was collected.	1993-11	1993-11
7	ALSPAC - Partners - 47 months ALSPAC - Partners - 47 months Start Date 1994-11 End Date 1997-01 Data sources Questionnaires Files No files could be found.	Information was collected about problems parents have from the Partner’s new questionnaire. In addition, information was collected about general physical health, mental health, diet and ...	1994-11	1997-01
8	ALSPAC - Partners - 61 months ALSPAC - Partners - 61 months Start Date 1996-01 End Date 1998-03 Data sources Questionnaires Files No files could be found.	Information was collected about lifestyle, the role in bringing up a child and any problems from the Study Partner’s Questionnaire. In addition, information was collected about general physical ...	1996-01	1998-03
9	ALSPAC - Partners - 73 months ALSPAC - Partners - 73 months Start Date 1997-02 End Date 1999-03 Data sources Questionnaires Files No files could be found.	Information was collected from the Partner’s Lifestyle Questionnaire. In addition, information was collected about general physical health, mental health, social characteristics, partner ...	1997-02	1999-03
10	ALSPAC - Partners - 85 months ALSPAC - Partners - 85 months Start Date 1998-08 End Date 2000-03 Data sources Questionnaires Files No files could be found.	Information was collected about accidents and injuries, the home, the household, how participant feels, occupation and lifestyle, and drinking, from the Partner and Home Questionnaire. In ...	1998-08	2000-03
11	ALSPAC - Partners - 97 months ALSPAC - Partners - 97 months Start Date 1999-09 End Date 2001-05 Data sources Questionnaires Files No files could be found.	Information was collected about life circumstances, health, diet and lifestyle from the Father and Family Questionnaire. In addition, information was collected about general physical health, ...	1999-09	2001-05
12	ALSPAC - Partners - 110 months ALSPAC - Partners - 110 months Start Date 2000-10 End Date 2002-04 Data sources Questionnaires Files No files could be found.	Information was collected about health, recent events, partner, family and friends, thoughts and feelings, and chemicals in the environment from the Father of a 9-Year-Old Questionnaire. In ...	2000-10	2002-04
13	ALSPAC - Partners - 122 months ALSPAC - Partners - 122 months Start Date 2001-08 End Date 2003-04 Data sources Questionnaires Files No files could be found.	Information was collected about activities, medications, occupation and lifestyle from the Father and Surroundings Questionnaire. In addition, information was collected about general ...	2001-08	2003-04
14	ALSPAC - Partners - 134 months ALSPAC - Partners - 134 months Start Date 2002-07 End Date 2004-05 Data sources Questionnaires Files No files could be found.	Information was collected about health problems you may have, as well as some features of your lifestyle from the Lifestyle and Health of Partner Questionnaire. In addition, information was ...	2002-07	2004-05
15	ALSPAC - Partners - 145 months ALSPAC - Partners - 145 months Start Date 2003-05 End Date 2005-05 Data sources Questionnaires Files No files could be found.	Information was collected about health, life in the last 4 weeks, partner, medications, breaking the law, family and friends, diet and environment from the About Me Questionnaire. In addition, ...	2003-05	2005-05
16	ALSPAC - Partners - Biosample collection 2004-2008 ALSPAC - Partners - Biosample collection 2004-2008 Start Date 2004-01 End Date 2008-12 Data sources Biosamples Data sources - Biosamples Blood Files No files could be found.	A blood sample was collected.	2004-01	2008-12
17	ALSPAC - Partners - 156 months ALSPAC - Partners - 156 months Start Date 2004-05 End Date 2004-10 Data sources Questionnaires Files No files could be found.	Information was collected about the types of adult learning undertaken, reasons for studying, location and methods of study and learning outcomes. In addition, information about attitudes to ...	2004-05	2004-10
18	ALSPAC - Partners - Biosample collection 2010 ALSPAC - Partners - Biosample collection 2010 Start Date 2010-05 End Date 2010-05 Data sources Biosamples Data sources - Biosamples Blood Files No files could be found.	A blood sample was collected.	2010-05	2010-05
19	ALSPAC - Partners - 20 years ALSPAC - Partners - 20 years Start Date 2011-01 End Date 2012-12 Data sources Questionnaires Files No files could be found.	Information was collected about mental health, social characteristics, partner information, parenting, housing and neighbourhood, and environmental characteristics. Social information such as ...	2011-01	2012-12
20	ALSPAC - Partners - 21/22 years ALSPAC - Partners - 21/22 years Start Date 2011-09 End Date 2013-02 Data sources Questionnaires Files No files could be found.	Information was collected about home life, neighborhood, family, friends, employment, coping with life, physical activity and lifestyle and health from the Focusing on You Questionnaire. ...	2011-09	2013-02
21	ALSPAC - Partners - Focus on father 1 ALSPAC - Partners - Focus on father 1 Start Date 2011-09 End Date 2013-02 Data sources Physical measures Files No files could be found.	Anthropometric measurements were taken. Also, a full body DXA Scan, a 3D face shape scan, a blood pressure, carotid intima media thickness, and a pulse wave velocity measurement were done.	2011-09	2013-02

Selection Criteria

Newborns

Twins

Countries

United Kingdom

Territory

Old administrative county of Avon, South West England.

Ethnic Origin

Health Status

Recruitment

Sources of recruitment

Specific population

Specific Population

Other specific population :
Children of the mothers recruited in ALSPAC.

Number of Participants

Number of Participants: 14,062
Number of Participants with Biological Samples: 10,000 (No Limit)
Supplementary Information about selection criteria

Data Collection Events

#	Name	Description	Start	End
0	ALSPAC - Children - Biosample collection birth ALSPAC - Children - Biosample collection birth Start Date 1991-04 End Date 1992-12 Data sources Biosamples Data sources - Biosamples Blood Tissues : cord slices Other : placenta Files No files could be found.	Blood samples, cord slices and placenta were collected.	1991-04	1992-12
1	ALSPAC - Children - 4 weeks ALSPAC - Children - 4 weeks Start Date 1991-04 End Date 1993-04 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages, Obstetric clinical records Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires and registries. Some questions were child based and some were child completed. A questionnaire collected information about ...	1991-04	1993-04
2	ALSPAC - Children - 6 months ALSPAC - Children - 6 months Start Date 1991-07 End Date 1993-08 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires and registries. Some questions were child based and some were child completed. A questionnaire specifically collected ...	1991-07	1993-08
3	ALSPAC - Children - Biosample collection 6 to 18 months ALSPAC - Children - Biosample collection 6 to 18 months Start Date 1991-10 End Date 1994-06 Data sources Biosamples Data sources - Biosamples Hair Nail Files No files could be found.	Hair and nail samples were collected.	1991-10	1994-06
4	ALSPAC - Children - 15 months ALSPAC - Children - 15 months Start Date 1992-08 End Date 1994-05 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaire collected information about ...	1992-08	1994-05
5	ALSPAC - Children - Children in focus 4 months ALSPAC - Children - Children in focus 4 months Start Date 1992-10 End Date 1993-04 Data sources Questionnaires Cognitive measures Physical measures Files No files could be found.	At the “children in focus” clinic, cognitive, environmental, physical, and seeing, hearing and speaking measures were taken. Information about diet, vision history, external eye ...	1992-10	1993-04
6	ALSPAC - Children - 18 months ALSPAC - Children - 18 months Start Date 1992-10 End Date 1994-08 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires and registries. Some questions were child based and some were child completed. Questionnaire specifically collected ...	1992-10	1994-08
7	ALSPAC - Children - 24 months ALSPAC - Children - 24 months Start Date 1993-01 End Date 1995-02 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaire specifically collected ...	1993-01	1995-02
8	ALSPAC - Children - Children in focus 8 months ALSPAC - Children - Children in focus 8 months Start Date 1993-02 End Date 1993-08 Data sources Questionnaires Physical measures Files No files could be found.	At the “children in focus” clinic, environmental, physical and seeing, hearing and speaking measures were taken. Information was collected about diet, vision history, external eye ...	1993-02	1993-08
9	ALSPAC - Children - Children in focus 12 months ALSPAC - Children - Children in focus 12 months Start Date 1993-06 End Date 1993-12 Data sources Questionnaires Physical measures Biosamples Data sources - Biosamples Blood Files No files could be found.	At the “children in focus” clinic, environmental, parenting, physical and seeing, hearing and speaking measures were taken. Information was collected about vision history, external eye ...	1993-06	1993-12
10	ALSPAC - Children - Children in focus 18 months ALSPAC - Children - Children in focus 18 months Start Date 1993-12 End Date 1994-06 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Files No files could be found.	At the “children in focus” clinic, cognitive, day care, environmental, physical and seeing, hearing and speaking measures were taken. Information was collected about day care, diet, ...	1993-12	1994-06
11	ALSPAC - Children - 30 months ALSPAC - Children - 30 months Start Date 1994-01 End Date 1995-08 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaire specifically collected ...	1994-01	1995-08
12	ALSPAC - Children - 38 months ALSPAC - Children - 38 months Start Date 1994-03 End Date 1996-04 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaire specifically collected ...	1994-03	1996-04
13	ALSPAC - Children - Biosample collection 3 years ALSPAC - Children - Biosample collection 3 years Start Date 1994-04 End Date 1995-12 Data sources Biosamples Data sources - Biosamples Hair Nail Files No files could be found.	A hair sample and a nail sample were collected.	1994-04	1995-12
14	ALSPAC - Children - Children in focus 25 months ALSPAC - Children - Children in focus 25 months Start Date 1994-07 End Date 1995-01 Data sources Questionnaires Cognitive measures Physical measures Files No files could be found.	At the “children in focus” clinic, day care, environmental, physical and seeing, hearing and speaking measures were taken. Information was collected about day care diet vision history ...	1994-07	1995-01
15	ALSPAC - Children - 42 months ALSPAC - Children - 42 months Start Date 1994-07 End Date 1996-10 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaire specifically collected ...	1994-07	1996-10
16	ALSPAC - Children - Children in focus 31 months ALSPAC - Children - Children in focus 31 months Start Date 1995-01 End Date 1995-07 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Files No files could be found.	At the “children in focus” clinic, physical and seeing, hearing and speaking measures were taken. Information about eye colour was collected. Anthropometry measures were ...	1995-01	1995-07
17	ALSPAC - Children - Biosample collection 4 years ALSPAC - Children - Biosample collection 4 years Start Date 1995-04 End Date 1996-12 Data sources Biosamples Data sources - Biosamples Hair Nail Files No files could be found.	A hair sample and nail sample were collected.	1995-04	1996-12
18	ALSPAC - Children - Children in focus 37 months ALSPAC - Children - Children in focus 37 months Start Date 1995-07 End Date 1996-01 Data sources Questionnaires Cognitive measures Physical measures Files No files could be found.	At the “children in focus” clinic, cognitive, daycare, environmental, physical and seeing, hearing and speaking measures were taken. Information was collected about day care, diet, ...	1995-07	1996-01
19	ALSPAC - Children - 54 months ALSPAC - Children - 54 months Start Date 1995-07 End Date 1997-08 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaire specifically collected ...	1995-07	1997-08
20	ALSPAC - Children - Children in focus 43 months ALSPAC - Children - Children in focus 43 months Start Date 1996-01 End Date 1996-07 Data sources Questionnaires Physical measures Biosamples Data sources - Biosamples Blood Files No files could be found.	At the “children in focus” clinic, daycare, environmental, physical and seeing, hearing and speaking measures were taken. Information was collected about day care and diet, eye colour, ...	1996-01	1996-07
21	ALSPAC - Children - 57 months ALSPAC - Children - 57 months Start Date 1996-01 End Date 1997-11 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaire specifically collected ...	1996-01	1997-11
22	ALSPAC - Children - Biosample collection 5 to 7 years ALSPAC - Children - Biosample collection 5 to 7 years Start Date 1996-04 End Date 1999-12 Data sources Biosamples Data sources - Biosamples Other : Teeth Files No files could be found.	A teeth sample was collected.	1996-04	1999-12
23	ALSPAC - Children - Children in focus 49 months ALSPAC - Children - Children in focus 49 months Start Date 1996-07 End Date 1997-01 Data sources Cognitive measures Physical measures Files No files could be found.	At the “children in focus” clinic, cognitive, physical and seeing, hearing and speaking measures were taken. Cognitive development was assessed. Anthropometry measures, blood ...	1996-07	1997-01
24	ALSPAC - Children - 65 months ALSPAC - Children - 65 months Start Date 1996-10 End Date 1998-07 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaires specifically collected ...	1996-10	1998-07
25	ALSPAC - Children - 69 months ALSPAC - Children - 69 months Start Date 1997-02 End Date 1998-12 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaires specifically collected ...	1997-02	1998-12
26	ALSPAC - Children - 73 months ALSPAC - Children - 73 months Start Date 1997-02 End Date 1999-03 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. At this time point the questionnaire was child completed. Questionnaire collected information from child’s ...	1997-02	1999-03
27	ALSPAC - Children - Children in focus 61 months ALSPAC - Children - Children in focus 61 months Start Date 1997-07 End Date 1998-04 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Files No files could be found.	At the “children in focus” clinic, cognitive, environmental, parenting, physical and seeing, hearing and speaking measures were taken. Information on diet and parenting was collected. ...	1997-07	1998-04
28	ALSPAC - Children - 77 months ALSPAC - Children - 77 months Start Date 1997-11 End Date 1999-07 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaires collected information about ...	1997-11	1999-07
29	ALSPAC - Children - 81 months ALSPAC - Children - 81 months Start Date 1998-03 End Date 1999-11 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaires specifically collected ...	1998-03	1999-11
30	ALSPAC - Children - Biosample collection 7 to 8 years ALSPAC - Children - Biosample collection 7 to 8 years Start Date 1998-04 End Date 2000-12 Data sources Biosamples Data sources - Biosamples Blood Urine Files No files could be found.	A blood and urine sample were collected.	1998-04	2000-12
31	ALSPAC - Children - 91 months ALSPAC - Children - 91 months Start Date 1998-07 End Date 2000-10 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaires specifically collected ...	1998-07	2000-10
32	ALSPAC - Children - 85 months ALSPAC - Children - 85 months Start Date 1998-08 End Date 2000-03 Data sources Questionnaires Files No files could be found.	Information was collected through the use of questionnaires, and registries. At this time point the questionnaire was child completed. Questionnaire collected information from child’s ...	1998-08	2000-03
33	ALSPAC - Children - Children in focus 7 years ALSPAC - Children - Children in focus 7 years Start Date 1998-09 End Date 2000-09 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Files No files could be found.	At the focus clinic, health, literacy/numeracy, motor skills, physiological and social information was assessed. Information was collected about food and activity, nutrition, general ...	1998-09	2000-09
34	ALSPAC - Children - 97 months ALSPAC - Children - 97 months Start Date 1999-09 End Date 2001-05 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. At this time point the questionnaire was child completed. Questionnaire specifically collected information ...	1999-09	2001-05
35	ALSPAC - Children - Children in focus 8 years ALSPAC - Children - Children in focus 8 years Start Date 1999-10 End Date 2001-12 Data sources Questionnaires Physical measures Files No files could be found.	At the focus clinic, motor skills, physiological, psychological and social information was assessed. Information about friends and peers was collected. Psychological measure ...	1999-10	2001-12
36	ALSPAC - Children - 103 months ALSPAC - Children - 103 months Start Date 2000-05 End Date 2001-09 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaires specifically collected ...	2000-05	2001-09
37	ALSPAC - Children - 110 months ALSPAC - Children - 110 months Start Date 2000-10 End Date 2002-04 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. At this time point the questionnaire was child completed. Questionnaire specifically collected information ...	2000-10	2002-04
38	ALSPAC - Children - Children in focus 9 years ALSPAC - Children - Children in focus 9 years Start Date 2001-01 End Date 2003-01 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Files No files could be found.	At the focus clinic, health, literacy/numeracy, physiological information was assessed. Reading skills were assessed. Fitness, hearing, and oto-acoustic emissions were ...	2001-01	2003-01
39	ALSPAC - Children - 115 months ALSPAC - Children - 115 months Start Date 2001-02 End Date 2002-11 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaires specifically collected ...	2001-02	2002-11
40	ALSPAC - Children - 122 months ALSPAC - Children - 122 months Start Date 2001-11 End Date 2003-04 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. At this time point the questionnaire was child completed. Questionnaire specifically collected information ...	2001-11	2003-04
41	ALSPAC - Children - Children in focus 10 years ALSPAC - Children - Children in focus 10 years Start Date 2002-02 End Date 2003-10 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Urine Saliva Files No files could be found.	At the focus clinic, health, physiological, psychological and social information was assessed. Information was collected about food and activity, nutrition, and antisocial activities. ...	2002-02	2003-10
42	ALSPAC - Children - 128 months ALSPAC - Children - 128 months Start Date 2002-02 End Date 2003-11 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaires collected information about ...	2002-02	2003-11
43	ALSPAC - Children - 134 months ALSPAC - Children - 134 months Start Date 2002-07 End Date 2004-05 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. At this time point the questionnaire was child completed. Questionnaire specifically collected information ...	2002-07	2004-05
44	ALSPAC - Children - 140 months ALSPAC - Children - 140 months Start Date 2002-12 End Date 2004-11 Data sources Questionnaires Cognitive measures Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questionnaires were child based and some were child completed. Questionnaires specifically collected ...	2002-12	2004-11
45	ALSPAC - Children - Children in focus 11 years ALSPAC - Children - Children in focus 11 years Start Date 2003-01 End Date 2005-01 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Saliva Files No files could be found.	At the focus clinic, health, motor skills, physiological, psychological and social information was assessed. Borderline personality disorder, romantic relations, and friendships were ...	2003-01	2005-01
46	ALSPAC - Children - 145 months ALSPAC - Children - 145 months Start Date 2003-05 End Date 2005-05 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaires specifically collected ...	2003-05	2005-05
47	ALSPAC - Children - Teen in focus 12 years ALSPAC - Children - Teen in focus 12 years Start Date 2004-02 End Date 2005-11 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Urine Saliva Files No files could be found.	At the focus clinic, literacy/numeracy, motor skills, psychological and social information were assessed. Antisocial activities, depression, parent-child interaction, psychosis, ...	2004-02	2005-11
48	ALSPAC - Children - 157 months ALSPAC - Children - 157 months Start Date 2004-05 End Date 2006-04 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaires specifically collected ...	2004-05	2006-04
49	ALSPAC - Children - Teen in focus 13 years ALSPAC - Children - Teen in focus 13 years Start Date 2005-01 End Date 2006-09 Data sources Questionnaires Physical measures Biosamples Data sources - Biosamples Blood Urine Files No files could be found.	At the focus clinic, health, psychological, and puberty information was assessed. Nutrition and menstruation information was collected. Personality was assessed as well. ...	2005-01	2006-09
50	ALSPAC - Children - 166 months ALSPAC - Children - 166 months Start Date 2005-07 End Date 2006-12 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaires specifically collected ...	2005-07	2006-12
51	ALSPAC - Children - 167 months ALSPAC - Children - 167 months Start Date 2005-09 End Date 2007-01 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. At this time point the questionnaire was child completed. Questionnaire specifically collected information ...	2005-09	2007-01
52	ALSPAC - Children - 169 months ALSPAC - Children - 169 months Start Date 2006-01 End Date 2007-03 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. At this time point the questionnaire was child completed. Questionnaire specifically collected information ...	2006-01	2007-03
53	ALSPAC - Children - Teen in focus 15 years ALSPAC - Children - Teen in focus 15 years Start Date 2006-10 End Date 2008-11 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Urine Saliva Hair Files No files could be found.	At the focus clinic, health, physiological, psychological and puberty information was assessed. Information was collected about puberty. Inhibition and IQ were measured. ...	2006-10	2008-11
54	ALSPAC - Children - 192 months ALSPAC - Children - 192 months Start Date 2007-03 End Date 2009-02 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaires collected information about ...	2007-03	2009-02
55	ALSPAC - Children - Biosample collection 17 years ALSPAC - Children - Biosample collection 17 years Start Date 2008-04 End Date 2009-12 Data sources Biosamples Data sources - Biosamples Blood Urine Hair Files No files could be found.	A blood, hair, and urine sample was collected.	2008-04	2009-12
56	ALSPAC - Children - 17 years ALSPAC - Children - 17 years Start Date 2008-04 End Date 2010-12 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaires were child completed. Information was collected from the “you and your friends”, “internet ...	2008-04	2010-12
57	ALSPAC - Children - 198 months ALSPAC - Children - 198 months Start Date 2008-10 End Date 2009-09 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Some questions were child based and some were child completed. Questionnaires specifically ...	2008-10	2009-09
58	ALSPAC - Children - Teen in focus 17 years ALSPAC - Children - Teen in focus 17 years Start Date 2008-12 End Date 2011-06 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Urine Saliva Hair Files No files could be found.	At the focus clinic, health, physiological, psychological and puberty information was assessed. Information was collected about antisocial activities, depression, psychosis, romantic ...	2008-12	2011-06
59	ALSPAC - Children - 18 years ALSPAC - Children - 18 years Start Date 2010-09 End Date 2011-05 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaire was child completed. Questionnaire specifically collected information about how time’s spent, ...	2010-09	2011-05
60	ALSPAC - Children - 19 years ALSPAC - Children - 19 years Start Date 2011-10 End Date 2012-01 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected on education, employment, relationships with friends and family, and overall well-being. Data on bladder health and puberty-related topics, such as menstruation and body ...	2011-10	2012-01
61	ALSPAC - Children - Biosample collection 21 to 22 years ALSPAC - Children - Biosample collection 21 to 22 years Start Date 2012-04 End Date 2014-12 Data sources Biosamples Data sources - Biosamples Blood Urine Files No files could be found.	A blood and urine sample was collected.	2012-04	2014-12
62	ALSPAC - Children - 20 years ALSPAC - Children - 20 years Start Date 2012-09 End Date 2013-07 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaire was child completed. Questionnaire specifically collected information about any children, ...	2012-09	2013-07
63	ALSPAC - Children - 21 years ALSPAC - Children - 21 years Start Date 2013-12 End Date 2014-10 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaires were child completed. Information about mental health, sexual health, general health and ...	2013-12	2014-10
64	ALSPAC - Children - 22 years ALSPAC - Children - 22 years Start Date 2014-11 End Date 2015-10 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaires were child completed. Information about health, physical activity, vision, substance use, ...	2014-11	2015-10
65	ALSPAC - Children - Biosample collection 24 to 25 years ALSPAC - Children - Biosample collection 24 to 25 years Start Date 2015-04 End Date 2017-12 Data sources Biosamples Data sources - Biosamples Blood Urine Files No files could be found.	A blood and urine sample was collected.	2015-04	2017-12
66	ALSPAC - Children - Children in focus 24 years ALSPAC - Children - Children in focus 24 years Start Date 2015-06 End Date 2017-09 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood Urine Files No files could be found.	Information about depression, psychotic experiences, alcohol, substance use, victimisation and trauma, moods and feelings, antisocial behaviour, reproductive health was collected through ...	2015-06	2017-09
67	ALSPAC - Children - 23 years ALSPAC - Children - 23 years Start Date 2015-12 End Date 2016-09 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaires were child completed. Information about social media, sexual experience, wellbeing, eating ...	2015-12	2016-09
68	ALSPAC - Children - 24 years ALSPAC - Children - 24 years Start Date 2016-11 End Date 2017-08 Data sources Questionnaires Administrative databases Other : Geo-spatial linkages Data sources - Administrative databases Health databases Socioeconomic databases Files No files could be found.	Information was collected through the use of questionnaires, and registries. Questionnaires were child completed. Information about social media usage, gambling, eating behaviour, ...	2016-11	2017-08
69	ALSPAC - Children - 25 years ALSPAC - Children - 25 years Start Date 2017-11 End Date 2018-07 Data sources Questionnaires Files No files could be found.	Information was collected about being a parent, and obtains details of any children born; about strengths and difficulties; about anxiety; information on healthcare and accidents; behaviour, ...	2017-11	2018-07
70	ALSPAC - Children - 26 years ALSPAC - Children - 26 years Start Date 2018-11 End Date 2019-09 Data sources Questionnaires Files No files could be found.	Information was collected about health, well-being, physical activity, behaviour, monetary choice, life events, family and fertility, unusual experiences, education, attitudes to data sharing.	2018-11	2019-09
71	ALSPAC - Children - 27 years ALSPAC - Children - 27 years Start Date 2019-11 End Date 2020-07 Data sources Questionnaires Files No files could be found.	Information was collected on childhood, faith and beliefs, feelings, parenting, and aspirations. Data on employment, education, family structure, life events, income, quality of life, ethnicity, ...	2019-11	2020-07

Selection Criteria

Newborns

Twins

Countries

United Kingdom

Territory

Old administrative county of Avon.

Ethnic Origin

Health Status

Recruitment

Sources of recruitment

Specific population

Specific Population

Other specific population :
Children of the children recruited in ALSPAC.

Number of Participants

Number of Participants: 1,100
Number of Participants with Biological Samples: 1,000

Data Collection Events

#	Name	Description	Start	End
0	ALSPAC - Generation 2 - Birth ALSPAC - Generation 2 - Birth Start Date 2012 End Date 2019 Data sources Physical measures Biosamples Data sources - Biosamples Tissues : Placenta, cord Other : meconium Files No files could be found.	Information was collected about child measurements by midwife or from health records. Biosamples were also collected including cord, placenta, meconium.	2012	2019
1	ALSPAC - Generation 2 - 7 to 15 days ALSPAC - Generation 2 - 7 to 15 days Start Date 2012 End Date 2019 Data sources Questionnaires Physical measures Biosamples Administrative databases Data sources - Biosamples Cord blood Tissues : Placenta Other : Meconium, stool Data sources - Administrative databases Health databases Files No files could be found.	Information was collected about feeding and general health (from parent). At the “children in focus” clinic, anthropometry and skinfold measures were taken. Meconium, cord ...	2012	2019
2	ALSPAC - Generation 2 - 6 months ALSPAC - Generation 2 - 6 months Start Date 2012 End Date 2019 Data sources Questionnaires Cognitive measures Physical measures Biosamples Administrative databases Data sources - Biosamples Other : Stools Data sources - Administrative databases Health databases Files No files could be found.	Information was collected about diet, general health, prescription and non-prescription medication, parent, grandparent, sibling interaction asthma/ eczema, allergies, activities/play, ...	2012	2019
3	ALSPAC - Generation 2 - 12 months ALSPAC - Generation 2 - 12 months Start Date 2013 End Date 2019 Data sources Questionnaires Cognitive measures Physical measures Biosamples Administrative databases Data sources - Biosamples Other : Stools Data sources - Administrative databases Health databases Files No files could be found.	Information was collected about feeding, general health, prescription and non-prescription medication, parent, grandparent, sibling interaction asthma/ eczema, allergies, activities/play, ...	2013	2019
4	ALSPAC - Generation 2 - 24 months ALSPAC - Generation 2 - 24 months Start Date 2014 End Date 2019 Data sources Questionnaires Cognitive measures Physical measures Administrative databases Data sources - Administrative databases Health databases Files No files could be found.	Information was collected about feeding, general health, prescription and non-prescription medication, parent, grandparent, sibling interaction, allergies, activities/play, temperament, and ...	2014	2019
5	ALSPAC - Generation 2 - 36 months ALSPAC - Generation 2 - 36 months Start Date 2015 End Date 2019 Data sources Questionnaires Cognitive measures Physical measures Biosamples Administrative databases Data sources - Biosamples Blood Saliva Data sources - Administrative databases Health databases Files No files could be found.	Information was collected about feeding, general health, prescription and non-prescription medication, parent, grandparent, sibling interaction, asthma/ eczema, allergies, activities/play, ...	2015	2019
6	ALSPAC - Generation 2 - 48 months ALSPAC - Generation 2 - 48 months Start Date 2016 End Date 2019 Data sources Questionnaires Cognitive measures Physical measures Administrative databases Data sources - Administrative databases Health databases Files No files could be found.	Information was collected about feeding, diet, general health, prescription and non-prescription medication, parent, grandparent, sibling interaction, asthma/ eczema, allergies, ...	2016	2019
7	ALSPAC - Generation 2 - 60 months ALSPAC - Generation 2 - 60 months Start Date 2017 End Date 2019 Data sources Questionnaires Cognitive measures Physical measures Biosamples Administrative databases Data sources - Biosamples Other : Stools Data sources - Administrative databases Health databases Files No files could be found.	Information was collected about feeding, diet, general health, prescription and non-prescription medication, asthma/ eczema, allergies, activities/play, screen time, temperament, behavior and ...	2017	2019
8	ALSPAC - Generation 2 - 72 months ALSPAC - Generation 2 - 72 months Start Date 2018 End Date 2019 Data sources Questionnaires Cognitive measures Physical measures Biosamples Administrative databases Data sources - Biosamples Blood Saliva Data sources - Administrative databases Health databases Files No files could be found.	Information was collected about general health, prescription and non-prescription medication, parents, grandparent, sibling interaction, asthma/ eczema, allergies, activities/play, ...	2018	2019
9	ALSPAC - Generation 2 - 84 months ALSPAC - Generation 2 - 84 months Start Date 2019 End Date 2019 Data sources Questionnaires Physical measures Administrative databases Data sources - Administrative databases Health databases Files No files could be found.	Information was collected about feeding, diet, general health, prescription and non-prescription medication, parents, grandparent, sibling interaction, asthma/ eczema, allergies, ...	2019	2019

Selection Criteria

Newborns

Twins

Countries

United Kingdom

Territory

Old administrative county of Avon.

Ethnic Origin

Health Status

Recruitment

Sources of recruitment

Specific population

Specific Population

Other specific population :
Siblings of the children recruited in ALSPAC.

Number of Participants

Number of Participants: 1,800 (No Limit)
Number of Participants with Biological Samples
Supplementary Information about selection criteria: Initial target is 1800 (but not limited to this)

Data Collection Event

Start Date: 2014
End Date: 2015

Data sources

Questionnaires
Biosamples

Data sources - Biosamples

Saliva

Selection Criteria

Newborns

Twins

Countries

United Kingdom

Territory

Old administrative county of Avon.

Ethnic Origin

Health Status

Recruitment

Sources of recruitment

Specific population

Specific Population

Other specific population :
Grandparents of the children recruited in ALSPAC.

Number of Participants

Number of Participants: 1,000
Number of Participants with Biological Samples
Supplementary Information about selection criteria: Initital target for einrollment is 1000 (but not limited to this)

Data Collection Event

Start Date: 2014-09
End Date: 2015

Data sources

Questionnaires
Biosamples

Data sources - Biosamples

Saliva

Classifications

Socio-demographic and economic characteristics
Lifestyle and behaviours
Birth, pregnancy and reproductive health history
Perception of health, quality of life, development and functional limitations
Diseases
Symptoms and signs
Medication and supplements
Non-pharmacological interventions
Health and community care services utilization
Death
Physical measures and assessments
Laboratory measures
Cognition, personality and psychological measures and assessments
Life events, life plans, beliefs and values
Preschool, school and work life
Social environment and relationships
Physical environment
Administrative information

Cognitive functioning
Personality
Psychological distress and emotions
Other psychological measures and assessments

Life events
Beliefs and values

Perception of health
Quality of life
Life course development
Functional limitations
Other perception of health, quality of life and functional limitation-related information

Tobacco
Alcohol
Drugs
Nutrition
Breastfeeding
Physical activity
Sleep
Sexual behaviours and orientation
Technological devices
Misbehaviour and criminality
Other and unspecified lifestyle information

Social network
Social participation
Social support
Parenting and familial environment
Other social environment characteristics

Socio-demographic and economic characteristics

Age/birthdate

Sex/gender

Twin

Marital/partner status

Family and household structure

Education

Residence

Birthplace

Ethnicity, race and religion

Language

Labour force and retirement

Income, possessions, and benefits

Other socio-demographic and economic characteristics

Lifestyle and behaviours

Tobacco

Alcohol

Drugs

Nutrition

Breastfeeding

Physical activity

Transportation

Personal hygiene

Sleep

Sexual behaviours and orientation

Leisure activities

Technological devices

Misbehaviour and criminality

Other and unspecified lifestyle information

Birth, pregnancy and reproductive health history

Puberty, menstruation, menopause and andropause

Contraception

Pregnancy, delivery and birth

Fertility and sexual health

Other reproductive health-related information

Perception of health, quality of life, development and functional limitations

Perception of health

Quality of life

Life course development

Functional limitations

Use of assistive devices

Other perception of health, quality of life and functional limitation-related information

Diseases

Certain infectious and parasitic diseases (A00-B99)

Neoplasms (C00-D48)

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Endocrine, nutritional and metabolic diseases (E00-E90)

Mental and behavioural disorders (F00-F99)

Diseases of the nervous system (G00-G99)

Diseases of the eye and adnexa (H00-H59)

Diseases of the ear and mastoid process (H60-H95)

Diseases of the circulatory system (I00-I99)

Diseases of the respiratory system (J00-J99)

Diseases of the digestive system (K00-K93)

Diseases of the skin and subcutaneous tissue (L00-L99)

Diseases of the musculoskeletal system and connective tissue (M00-M99)

Diseases of the genitourinary system (N00-N99)

Pregnancy, childbirth and the puerperium (O00-O9A)

Certain conditions originating in the perinatal period (P00-P96)

Congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)

Injury, poisoning and certain other consequences of external causes (S00-T98)

External causes of morbidity and mortality (V01-Y98)

Diseases without precise specification or falling into multiple categories

Symptoms and signs

Symptoms and signs involving the circulatory and respiratory systems (R00-R09)

Symptoms and signs involving the digestive system and abdomen (R10-R19)

Symptoms and signs involving the skin and subcutaneous tissue (R20-R23)

Symptoms and signs involving nervous and musculoskeletal systems (R25-R29)

Symptoms and signs involving the urinary system (R30-R39)

Symptoms and signs involving cognition, perception, emotional state and behaviour (R40-R46)

Symptoms and signs involving speech and voice (R47-R49)

General symptoms and signs (R50-R69)

Symptoms related to multiple categories

Medication and supplements

Medication and supplement intake

Posology and protocol of administration

Other and unspecified pharmacological interventions

Non-pharmacological interventions

Surgical interventions

Radiological interventions

Physical therapy interventions

Cognitive, psychological and sensory interventions

Educational and health promotion interventions

Laboratory diagnosis interventions

Other and unspecified non-pharmacological interventions

Health and community care services utilization

Visits to health professionals

Hospitalizations

Community and social care

Other health and community care

Death

Vital status

Physical measures and assessments

Physical characteristics

Anthropometry

Circulation and respiration

Muscles, skeleton and mobility

Sensory and pain

Brain and nerves

Skin and subcutaneous tissue

Speech and voice

Digestion

Other physical measures and assessments

Laboratory measures

Hematology

Biochemistry

Microbiology

Virology

Immunology

Other laboratory measures

Cognition, personality and psychological measures and assessments

Cognitive functioning

Personality

Psychological distress and emotions

Other psychological measures and assessments

Life events, life plans, beliefs and values

Life events

Life plans

Beliefs and values

Preschool, school and work life

Preschool life

School life

Work life

Other preschool, school or work life-related information

Social environment and relationships

Social network

Social participation

Social support

Parenting and familial environment

Other social environment characteristics

Physical environment

Housing characteristics

Built environment/neighbourhood characteristics

Workplace characteristics

Radiation exposure

Chemical exposure

Biological exposure

Other physical environment characteristics

Administrative information

Identifiers

Date and time-related information

Questionnaire and interview-related information

Physical and cognitive measure and biosample-related information

Data and sample collection center-related information

Other administrative information

Cognitive functioning

Affective Go/No-Go Task

Backward Digit Span Task

Bicycle Drawing Task

Children's Communication Checklist

Children's Test of Nonword Repetition

Choice Reaction Time Task

Diagnostic Analysis of Nonverbal Accuracy

Digit Vigilance Test

Emotion Recognition Task

Emotional Triangles Task

Infant-Controlled Habituation Test

MacArthur-Bates Communicative Development Inventories

Neale Analysis of Reading Ability

N-Back Task

Probabilistic Reversal Learning Task

Renfrew Bus Story Language Screening

Reynell Developmental Language Scales

Simple Reaction Time Task

Stop Signal Task

Spoonerism Task

Spot the Word Test

Test of Everyday Attention for Children

Test of Word Reading Efficiency

Verbal Fluency

Wechsler Adult Intelligence Scale (Coding)

Wechsler Abbreviated Scale of Intelligence Full Scale IQ

Wechsler Intelligence Scale for Children

Wechsler Memory Scale (Digit Span)

Wechsler Memory Scale (Logical memory)

Wechsler Objective Language Dimensions

Wechsler Objective Reading Dimensions

Wechsler Preschool and Primary Scale of Intelligence

Working Memory Span Tasks

Personality

Arnett Inventory of Sensation Seeking

Big Five Inventory

Childhood Interview for DSM-IV Borderline Personality Disorder

Carey Infant Temperament Scale

Cognitive Style Questionnaire

Emotionality, Activity and Sociability Temperament Survey

General Self-Efficacy Scale

Interpersonal Sensitivity Measure

Karolinska Scales of Personality

Life Orientation Test

Rosenberg Self-Esteem Scale

Revised Rutter Parent Scale for Preschool Children

Reading Self-Concept Scale

Standardised Assessment of Personality - Abbreviated Scale

Strengths and Difficulties Questionnaire

Self-Description Questionnaire (Mathematics Scale)

Social Aptitudes Scale

Self Perception Profile for Children

Urgency, Premeditation, Perseverance, Sensation Seeking, Positive Urgency, Impulsive Behavior Scale

Psychological distress and emotions

Anxiety Sensitivity Index

Body Dissatisfaction Scale

Body Shape Questionnaire

Comprehensive Assessment of At-Risk Mental States

Community Assessment of Psychic Experiences

Clinical Interview Schedule Revised

Development and Well-Being Assessment

Eating Disorder Examination

Edinburgh Postnatal Depression Scale

Generalized Anxiety Disorder Scale

Hypomania Checklist

International Trauma Questionnaire

Mood and Feelings Questionnaire

Middlesex Hospital Questionnaire

McKnight Risk Factor Survey

PTSD Checklist for DSM-5

Psychosis-Like Symptoms Interview

Perceived Sociocultural Pressure Scale

Spielberger State-Trait Anxiety Inventory

Life events

Adverse Childhood Experiences Questionnaire

Bullying and Friendship Interview Schedule

Conflict Tactics Scale

Stressful Life Event Questionnaire

Beliefs and values

Dysfunctional Attitude Scale

The Duke University Religion Index

Iowa Infant Feeding Attitude Scale

Locus of Control Behaviour Scale

Nowicki-Strickland Locus of Control Scale

Quality of life

Basic Needs Satisfaction in General Scale

Dartmouth Cooperative Information Project Functional Assessment Charts

Gratitude Questionnaire

Life Satisfaction Questionnaire

Meaning in Life Questionnaire

Meaning in Life Scale

Short-Form 12 Health Survey

Short-Form 36 Health Survey

Subjective Happiness Scale

Satisfaction with Life Scale

Warwick-Edinburgh Mental Wellbeing Scale

Life course development

Denver Developmental Screening Test

Griffith Mental Development Scales

Preschool Activities Inventory

Skuse Social Cognition Scale

Social Responsiveness Scale

Functional limitations

European Male Ageing Study Sexual Function Questionnaire

Tobacco

Fagerström Test for Nicotine Dependence

Alcohol

Alcohol Use Disorders Identification Test

Escape Questionnaire

Important People and Activities Instrument

Self-Rating of the Effects of Alcohol Questionnaire

Drugs

Cannabis Abuse Screening Test

Nutrition

Adult Eating Behaviour Questionnaire

Food Frequency Questionnaire (different forms)

Sexual behaviours and orientation

Adolescent Sexuality Activity Index

Misbehaviour and criminality

Antisocial Behavior Scale

DSM-IV Pathological Gambling Diagnostic Form

Problem Gambling Severity Index

Self-Report Delinquency Scale

Social support

Cambridge Hormones and Moods Project Friendship Questionnaire

Intimate Bond Measure

Social Support Questionnaire

Parenting and familial environment

Etch-A-Sketch Task

Confusion, Hubbub, and Order Scale

Home Observation for Measurement of Environment

Maternal Bonding Score

Parental Bonding Instrument

Thorpe Interaction Measure

Individual Study / ALSPAC

Avon Longitudinal Study of Parents and Children

Members

Paul Burton

George Smith

Nicholas Timpson

Lynn Molloy

Design

Marker Paper

Recruitment

Number of Participants

Access

Timeline

Populations

Selection Criteria

Recruitment

Number of Participants

Files

Data Collection Events

ALSPAC - Mothers - Biosample collection 1990 to 1992

ALSPAC - Mothers - 8 to 42 weeks gestation

ALSPAC - Mothers - 18 weeks gestation

ALSPAC - Mothers - 12 weeks gestation

ALSPAC - Mothers - 32 weeks gestation

ALSPAC - Mothers - 8 weeks

ALSPAC - Mothers - 8 months

ALSPAC - Mothers - 21 months

ALSPAC - Mothers - 33 months

ALSPAC - Mothers - Biosample collection 1993

ALSPAC - Mothers - 47 months

ALSPAC - Mothers - 61 months

ALSPAC - Mothers - 73 months

ALSPAC - Mothers - 85 months

ALSPAC - Mothers - 97 months

ALSPAC - Mothers - 110 months

ALSPAC - Mothers - 122 months

ALSPAC - Mothers - 134 months

ALSPAC - Mothers - 145 months

ALSPAC - Mothers - Biosample collection 2004 to 2008

ALSPAC - Mothers - 156 months

ALSPAC - Mothers - Focus on mothers 1

ALSPAC - Mothers - 18 years

ALSPAC - Mothers - Focus on mothers 2

ALSPAC - Mothers - 20 years

ALSPAC - Mothers - 22 years

ALSPAC - Mothers - Focus on mothers 3

ALSPAC - Mothers - Focus on mothers 4

Selection Criteria

Recruitment

Number of Participants

Files

Data Collection Events

ALSPAC - Partners - 18 weeks gestation

ALSPAC - Partners - 12 weeks gestation

ALSPAC - Partners - 8 weeks

ALSPAC - Partners - 8 months

ALSPAC - Partners - 21 months

ALSPAC - Partners - 33 months

ALSPAC - Partners - Biosample collection 1993

ALSPAC - Partners - 47 months

ALSPAC - Partners - 61 months

ALSPAC - Partners - 73 months

ALSPAC - Partners - 85 months

ALSPAC - Partners - 97 months

ALSPAC - Partners - 110 months

ALSPAC - Partners - 122 months

ALSPAC - Partners - 134 months

ALSPAC - Partners - 145 months

ALSPAC - Partners - Biosample collection 2004-2008

ALSPAC - Partners - 156 months

ALSPAC - Partners - Biosample collection 2010

ALSPAC - Partners - 20 years

ALSPAC - Partners - 21/22 years

ALSPAC - Partners - Focus on father 1

Selection Criteria

Recruitment

Number of Participants

Files

Data Collection Events

ALSPAC - Children - Biosample collection birth