Atma Jaya Cognitive and Aging Research
The objective of the Atma Jaya Cognitive and Aging Research is to investigate the relationship between the presence of APOE 𝜀4 genotype in the elderly and cognitive function.
- Start Year
- 2011
- Supplementary Information
-
Rolland Y, Resnick B, Katz PR, et al. Nursing home research: the first International Association of Gerontology and Geriatrics (IAGG) research conference. Journal of American Medical Directors Association. 2014 ;15(5):313-25.
Turana Y, Widjaja NT, Handajani YS. Association Between APOE Ε4 Genotype And Memory Impairment In Elderly With Normal Global Cognitive Assessment. Diagnostics 2015, 5(4), 615-623.
Kim BY, Lee SH, Graham PL, Angelucci F, et al. Peripheral Brain-Derived Neurotrophic Factor Levels in Alzheimer’s Disease and Mild Cognitive Impairment: a Comprehensive Systematic Review and Meta-analysis. Molecular Neurobiology. 2016; 2016.
| Investigators | Contacts |
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Design
- Study design
- Cohort
- Follow Up
- Assessment is scheduled at 2 years interval with interview.
- Supplementary Information
Marker Paper
Turana Y, Ranakusuma TAS, Purba JS, et al. Enhancing diagnostic accuracy of aMCI in the elderly: Combination of olfactory test, pupillary response test, BDNF plasma level, and APOE genotype. International Journal of Alzheimer's Disease, 2014; 2014.
PUBMED 24639912
Recruitment
- Recruitment Target
-
- Individuals
Number of Participants
- Number of Participants
- 860
- Number of Participants with Biological Samples
- 860
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
Timeline
AJCAR Population
Selection Criteria
- Minimum age
-
60
- Newborns
- Twins
- Countries
-
- Indonesia
- Territory
- Jakarta
- Ethnic Origin
-
- Asian
- Health Status
-
- Supplementary Information about selection criteria
Recruitment
- Sources of recruitment
-
- General population
- General Population
-
- Volunteer enrolment
Number of Participants
- Number of Participants
- 860
- Number of Participants with Biological Samples
- 860
Data Collection Event
The assessment collected information using questionnaires, cognitive tests, physical measures and laboratory measures.
Demographic information including age, gender, education and job was collected, as well as information about social and living condition, social support, medical support, medical history, activities of daily living and instrumental activities of daily living (Barthel), caregiver, healthy life style, social and religion aspects, perceived quality of life (nocturnal as well), depression (Geriatric Depression Scale - GDS), and multidimensional scale of perceived social support (MSPSS).
Cognitive function information was collected using the CERAD Neuropsychological Battery where memory, cognitive impairment, dementia, verbal fluency, confrontational word retrieval, and recognition were assessed.
Anthropometric measurements were taken and information about physical functioning outcomes and olfactory functioning was collected. Balance was measured (Berg Balance Scale - BBS) and a senior fitness test and a physical examination were performed. A bio-impedence analysis (BIA) was done to estimate body composition.
Blood samples were taken and information was collected from APOE genetic assessments. BDNF plasma levels were measured as well.
- Start Date
-
2011
- End Date
-
2019
- Data sources
-
- Questionnaires
- Cognitive measures
- Physical measures
- Biosamples
- Data sources - Biosamples
-
- Blood
Classifications
- Socio-demographic and economic characteristics
- Lifestyle and behaviours
- Birth, pregnancy and reproductive health history
- Perception of health, quality of life, development and functional limitations
- Diseases
- Symptoms and signs
- Medication and supplements
- Non-pharmacological interventions
- Health and community care services utilization
- Death
- Physical measures and assessments
- Laboratory measures
- Cognition, personality and psychological measures and assessments
- Life events, life plans, beliefs and values
- Preschool, school and work life
- Social environment and relationships
- Physical environment
- Administrative information
- Cognitive functioning
- Personality
- Psychological distress and emotions
- Other psychological measures and assessments
- Perception of health
- Quality of life
- Life course development
- Functional limitations
- Other perception of health, quality of life and functional limitation-related information
Socio-demographic and economic characteristics
Perception of health, quality of life, development and functional limitations
Diseases
Non-pharmacological interventions
Physical measures and assessments
Laboratory measures
Cognition, personality and psychological measures and assessments
Administrative information
Cognitive functioning
Psychological distress and emotions
Functional limitations