Individual Study / 50YMG

50-year-olds in Gothenburg
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50-year-olds in Gothenburg

Networks -
Datasets -
Variables -
Start Year
1963
End Year
2013
Supplementary Information
Additional paper(s)
Wilhelmsen L, Svärdsudd K, Eriksson H, et al. Factors associated with reaching 90 years of age: a study of men born in 1913 in Gothenburg, Sweden. J Intern Med. 2011 Apr;269(4):441-51. PUBMED: 21175902

Persson CU, Collén AC, Rosengren A, et al. Secular trends in cardiovascular risk factors among women aged 45-54 years in Gothenburg, Sweden, from 1980 to 2014. BMC Public Health. 2020 Jul 1;20(1):1042 PUBMED: 32611406
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Investigators Contacts
  • Prof. Per-Olof Hansson
    University of Gothenburg
  • Prof. Kurt Svärdsudd
    Uppsala University
  • Prof. Annika Rosengren
    University of Gothenburg
  • Prof. Lennart Welin
  • Prof. Per-Olof Hansson
    University of Gothenburg
  • Prof. Kurt Svärdsudd
    Uppsala University

Design

Study design
Cohort
Follow Up
Participants born in 1913 participated in the survey when they were 50 years old and were followed up when they were 54, 60, 67, 75 and 80 years old.

All participants were followed up until death or until December 31, 2011.

Marker Paper

Zhong Y, Rosengren A, Fu M, et al. Secular changes in cardiovascular risk factors in Swedish 50-year-old men over a 50-year period: The study of men born in 1913, 1923, 1933, 1943, 1953 and 1963. EUR J PREV CARDIOL. 2017 APR;24(6):612-620.

PUBMED 27794107

Recruitment

Recruitment Target
  • Individuals
  • Families

Number of Participants

Number of Participants
4,503
Number of Participants with Biological Samples
4,503
Supplementary Information
Since 1963, the study has been filled with new 50-year-olds, and since 2003 women are also included in the study. New samples of 50-year-old men were drawn in 1973, 1983, 1993-1994, 2003-2004 and 2013-2014.

  • Men born in 1913, 855 participants.
  • Men born in 1923, 226 participants.
  • Men born in 1933, 776 participants.
  • Men born in 1943, 798 participants.
  • Men born in 1953, 595 participants.
  • Men born in 1963, 313 participants.
  • Women born in 1953, 677 participants.
  • Sons to men born in 1913, 263 participants.

    • Access

    Availability of data and biosamples

    Possible Access to Data
    Possible Access to Biosamples
    Other
    Yes
    No
    Not applicable
    Don't know

    Timeline

    Populations

    Selection Criteria
    Sex
    Men
    Minimum age
    50
    Newborns
    Twins
    Countries
    • Sweden
    Territory
    Gothenburg
    Ethnic Origin
    Health Status
    Other Criteria
    Day of birth divisible by three.
    Supplementary Information about selection criteria
    Systematic representative sample based on birth date.

    Recruitment

    Sources of recruitment
    • General population
    General Population
    • Volunteer enrolment
    Supplementary Information
    In 1963, a sample was drawn from the Swedish population register consisting of all the men born in 1913 on a day divisible by three (e.g. the third, sixth, ninth day, and so on, of each month) and living in the city of Gothenburg.
    These criteria were met by 973 men, of whom 855 (87.9%) participated in the study.
    In addition, new cross-sectional samples of men born in 1913 and living in the city of Gothenburg were selected in 1973, 1980, 1988 and 1993 using the same criteria as in 1963.

    Number of Participants

    Number of Participants
    855
    Number of Participants with Biological Samples
    855
    Supplementary Information about selection criteria
    Data Collection Events
    # Name Description Start End
    0 50YMG - Men born 1913 - Baseline Information about smoking habits, physical activity, family history of myocardial infarction and occupation were assessed through questionnaires. Data from clinical examinations including mean ... 1963-01 1963-12
    1 50YMG - Men born 1913 - Follow-up 1 Information about smoking habits, physical activity, family history of myocardial infarction and occupation were assessed through questionnaires. Data from clinical examinations including mean ... 1967-01 1967-12
    2 50YMG - Men born 1913 - Follow-up 2 Information about smoking habits, physical activity, family history of myocardial infarction and occupation were assessed through questionnaires. Data from clinical examinations including mean ... 1973-01 1973-12
    3 50YMG - Men born 1913 - Follow-up 3 Information about smoking habits, physical activity, family history of myocardial infarction and occupation were assessed through questionnaires. Data from clinical examinations including mean ... 1980-01 1980-12
    4 50YMG - Men born 1913 - Follow-up 4 Information about smoking habits, physical activity, family history of myocardial infarction and occupation were assessed through questionnaires. Data from clinical examinations including mean ... 1988-01 1988-12
    5 50YMG - Men born 1913 - Follow-up 5 Information about smoking habits, physical activity, family history of myocardial infarction and occupation were assessed through questionnaires. Data from clinical examinations including mean ... 1993-01 1993-12
    7 50YMG - Men born 1913 - Follow-up 6 Mortality data were obtained from the National Cause of Death Register. All participants were followed up until death or until 31 December 2011. 2011-01 2011-12
    Selection Criteria
    Sex
    Women
    Minimum age
    50
    Newborns
    Twins
    Countries
    • Sweden
    Territory
    Gothenburg
    Ethnic Origin
    Health Status
    Supplementary Information about selection criteria

    Recruitment

    Sources of recruitment
    • General population
    General Population
    • Volunteer enrolment
    Supplementary Information
    In 2003 every third of all women born in 1953 were invited to participate in the study.

    Number of Participants

    Number of Participants
    667
    Number of Participants with Biological Samples
    667
    Supplementary Information about selection criteria
    Data Collection Events
    # Name Description Start End
    0 50YMG - Women born 1953 - Baseline Data on smoking habits, leisure-time physical activity, mental stress, previous diseases and pharmacological treatments were obtained by questionnaires. Physical measurements as height, body ... 2003 2003
    1 50YMG - Women born 1953 - Follow-up 1 Mortality data were obtained from the National Cause of Death Register. All participants were followed up until death or until 31 December 2021. 2021 2021
    Selection Criteria
    Sex
    Men
    Minimum age
    30
    Newborns
    Twins
    Countries
    • Sweden
    Territory
    Gothenburg
    Ethnic Origin
    Health Status
    Other Criteria
    Individuals are the sons to men born 1913 in Gothenburg and recruited to the study in 1963.
    Supplementary Information about selection criteria

    Recruitment

    Sources of recruitment
    • Specific population
    Specific Population
    • Other specific population : 30-year-old sons to men born in 1913 and living in Gothenburg.
    Supplementary Information
    In 1973, 30-year-old sons to the 50YMG - born 1913 population recruited in 1963, were asked to participate in a baseline examination. Only 263 subjects met the age selection criteria and were included in the study. In 1980, a new sample of 30-year-old sons to men born in 1913 were recruited via the National Board of Health and Welfare's register.

    Number of Participants

    Number of Participants
    33,263
    Number of Participants with Biological Samples
    33,263
    Supplementary Information about selection criteria
  • 263 participants recruited in 1973
  • 33000 participants recruited in 1980
    • Data Collection Events
    # Name Description Start End
    1 50YMG - Sons of men born 1913 - Baseline Information about smoking habits, physical activity, family history of myocardial infarction and occupation were assessed through questionnaires. Data from clinical examinations including mean ... 1973-01 1980-12
    2 50YMG - Sons of men born 1913 - Follow-up 1 Information about smoking habits, physical activity, family history of myocardial infarction and occupation were assessed through questionnaires. Data from clinical examinations including mean ... 1988-01 1988-12
    2 50YMG - Sons of men born 1913 - Follow-up 2 Information about smoking habits, physical activity, family history of myocardial infarction and occupation were assessed through questionnaires. Data from clinical examinations including mean ... 1993-01 1993-12
    3 50YMG - Sons of men born 1913 - Follow-up 3 Mortality data were obtained from the National Cause of Death Register. All participants were followed up until death or until 31 December 2011. 2011-01 2011-12
    4 50YMG - Sons of men born 1913 - Follow-up 4 Mortality data were obtained from the National Cause of Death Register. All participants were followed up until death or until 31 December 2021. 2021-01 2021-12
    Selection Criteria
    Sex
    Men
    Minimum age
    50
    Newborns
    Twins
    Countries
    • Sweden
    Territory
    Gothenburg
    Ethnic Origin
    Health Status
    Other Criteria
    Day of birth divisible by nine.
    Supplementary Information about selection criteria

    Recruitment

    Sources of recruitment
    • General population
    General Population
    • Volunteer enrolment
    Supplementary Information
    Systematic representative sample based on birth date. Participation rate 77.4%

    Number of Participants

    Number of Participants
    226
    Number of Participants with Biological Samples
    226
    Supplementary Information about selection criteria
    Data Collection Events
    # Name Description Start End
    0 50YMG - Men born 1923 - Baseline Information about smoking habits, physical activity, family history of myocardial infarction and occupatio were assessed through questionnaires. Data from clinical examinations including mean ... 1973-01 1973-12
    1 50YMG - Men born 1923 - Follow-up 1 Information about smoking habits, physical activity, family history of myocardial infarction and occupatio were assessed through questionnaires. Data from clinical examinations including mean ... 1980-01 1980-12
    2 50YMG - Men born 1923 - Follow-up 2 Information about smoking habits, physical activity, family history of myocardial infarction and occupatio were assessed through questionnaires. Data from clinical examinations including mean ... 1988-01 1988-12
    3 50YMG - Men born 1923 - Follow-up 3 Information about smoking habits, physical activity, family history of myocardial infarction and occupatio were assessed through questionnaires. Data from clinical examinations including mean ... 1993-01 1993-12
    4 50YMG - Men born 1923 - Follow-up 4 Mortality data were obtained from the National Cause of Death Register. All participants were followed up until death or until 31 December 2011. 2011-01 2011-12
    5 50YMG - Men born 1923 - Follow-up 5 Mortality data were obtained from the National Cause of Death Register. All participants were followed up until death or until 31 December 2021. 2021-01 2021-12
    Selection Criteria
    Sex
    Men
    Minimum age
    50
    Newborns
    Twins
    Countries
    • Sweden
    Territory
    Gothenburg
    Ethnic Origin
    Health Status
    Supplementary Information about selection criteria

    Recruitment

    Sources of recruitment
    • General population
    General Population
    • Selected sample
    Supplementary Information
    Randomly selected population sample. Participation rate 76.4%.

    Number of Participants

    Number of Participants
    776
    Number of Participants with Biological Samples
    776
    Supplementary Information about selection criteria
    Data Collection Events
    # Name Description Start End
    0 50YMG - Men born 1933 - Baseline Information about smoking habits, physical activity, family history of myocardial infarction and occupatio were assessed through questionnaires. Clinical examinations including mean body mass ... 1983-01 1984-12
    1 50YMG - Men born 1933 - Follow-up 1 Information about smoking habits, physical activity, family history of myocardial infarction and occupatio were assessed through questionnaires. Data from clinical examinations including mean ... 1991-01 1992-12
    Selection Criteria
    Sex
    Men
    Minimum age
    50
    Newborns
    Twins
    Countries
    • Sweden
    Territory
    Gothenburg
    Ethnic Origin
    Health Status

    Recruitment

    Sources of recruitment
    • General population
    General Population
    • Volunteer enrolment
    Supplementary Information
    Random population sample. Participation rate 54.5%

    Number of Participants

    Number of Participants
    798
    Number of Participants with Biological Samples
    798
    Supplementary Information about selection criteria
    Data Collection Events
    # Name Description Start End
    0 50YMG - Men born 1943 - Baseline Information about smoking habits, physical activity, family history of myocardial infarction and occupatio were assessed through questionnaires. Clinical examinations including mean body mass ... 1993-01 1994-12
    1 50YMG - Men born 1943 - Follow-up 1 Information about smoking habits, physical activity, family history of myocardial infarction and occupatio were assessed through questionnaires. Clinical examinations including mean body mass ... 2003-01 2003-12
    2 50YMG - Men born 1943 - Follow-up 2 Information about smoking habits, physical activity, family history of myocardial infarction and occupatio were assessed through questionnaires. Clinical examinations including mean body mass ... 2014-01 2014-12
    3 50YMG - Men born 1943 - Follow-up 3 Mortality data were obtained from the National Cause of Death Register. All participants were followed up until death or until 31 December 2021. 2021-01 2021-12
    Selection Criteria
    Sex
    Men
    Minimum age
    50
    Newborns
    Twins
    Countries
    • Sweden
    Territory
    Gothenburg
    Ethnic Origin
    Health Status

    Recruitment

    Sources of recruitment
    • General population
    General Population
    • Volunteer enrolment
    Supplementary Information
    Random population sample. Participation rate 59.9%

    Number of Participants

    Number of Participants
    677
    Number of Participants with Biological Samples
    677
    Supplementary Information about selection criteria
    Data Collection Events
    # Name Description Start End
    0 50YMG - Men born 1953 - Baseline Information about smoking habits, physical activity, family history of myocardial infarction and occupatio were assessed through questionnaires. Clinical examinations including mean body mass ... 2003-01 2004-12
    1 50YMG - Men born 1953 - Follow-up Mortality data were obtained from the National Cause of Death Register. All participants were followed up until death or until 31 December 2021. 2021-01 2021-12
    Selection Criteria
    Sex
    Men
    Minimum age
    50
    Newborns
    Twins
    Countries
    • Sweden
    Territory
    Gothenburg
    Ethnic Origin
    Health Status

    Recruitment

    Sources of recruitment
    • General population
    General Population
    • Volunteer enrolment
    Supplementary Information
    Random population sample. Participation rate 48.2%

    Number of Participants

    Number of Participants
    313
    Number of Participants with Biological Samples
    313
    Supplementary Information about selection criteria
    Data Collection Events
    # Name Description Start End
    0 50YMG - Men born 1963 - Baseline Information about smoking habits, physical activity, family history of myocardial infarction and occupatio were assessed through questionnaires. Clinical examinations including mean body mass ... 2013-01 2014-12
    1 50YMG - Men born 1963 - Follow-up Mortality data were obtained from the National Cause of Death Register. All participants were followed up until death or until 31 December 2021. 2021-01 2021-12
    Selection Criteria
    Sex
    Women
    Minimum age
    50
    Newborns
    Twins
    Countries
    • Sweden
    Territory
    Gothenburg
    Ethnic Origin
    Health Status
    Other Criteria
    Every fifth woman born in 1963.
    Supplementary Information about selection criteria

    Recruitment

    Sources of recruitment
    • General population
    General Population
    • Volunteer enrolment
    Supplementary Information
    Participation rate 53%.

    Number of Participants

    Number of Participants
    343
    Number of Participants with Biological Samples
    343
    Supplementary Information about selection criteria
    Data Collection Event
    Start Date
    2013-10
    End Date
    2014-04
    Data sources
    • Questionnaires
    • Physical measures
    • Biosamples
    Data sources - Biosamples
    • Blood

    Classifications

    Socio-demographic and economic characteristics
    Lifestyle and behaviours
    Birth, pregnancy and reproductive health history
    Perception of health, quality of life, development and functional limitations
    Diseases
    Symptoms and signs
    Medication and supplements
    Non-pharmacological interventions
    Health and community care services utilization
    Death
    Physical measures and assessments
    Laboratory measures
    Cognition, personality and psychological measures and assessments
    Life events, life plans, beliefs and values
    Preschool, school and work life
    Social environment and relationships
    Physical environment
    Administrative information

    Socio-demographic and economic characteristics

    Lifestyle and behaviours

    Diseases

    Medication and supplements

    Non-pharmacological interventions

    Death

    Physical measures and assessments

    Laboratory measures

    Cognition, personality and psychological measures and assessments

    Administrative information