WHISCA_Estrogen_followup
Population
WHISCA - Estrogen hormone therapy
The participants in the estrogen hormone therapy group (conjugated equine estrogens 0.625mg/day) were hysterectomized women, enrolled in the WHIMS study and the HRT trial of the WHI, who were aged 66 to 84 years at the time of WHISCA enrollment in 1999-2001.
Data Collection Event
WHISCA - Follow-up
Detailed cognitive function and affect assessments occurred during each WHISCA visit. Tests were chosen based on their sensitivity to age-related and hormone-related changes and included tests on global cognition, verbal knowledge, verbal fluency, figural memory, verbal memory, attention and working memory, spatial ability, fine motor speed and affect.
Anthropometric measurements were done including weight and height. BMI was calculated. Waist circumference was measured at years 1, 3 and 6.
Information was also obtained on age, caloric intake, dieting history, physical activity, race/ethnicity, education, hypertension, smoking, history of stroke, heart disease, diabetes, alcohol intake, and WHI treatment assignment. Dementia diagnostics were obtained from WHIMS.