Collected Dataset / CPDDN_PhaseIII_MSChildren_Follow-up_1year

The population is composed of Canadian children aged younger than 17 years and 11 months who met criteria for multiple sclerosis (MS), to any of the 16 paediatric health-care facilities or seven regional health-care facilities in Canada or in the United States of America and were enrolled within 90 days of symptom onset.

Information was collected from participants and/or guardian through interviews which collected information about medications, smoke exposure, travel history, family, education. Additionally, questionnaires were used to collect the PedsQL, Barratt Simplified Measure of Social Status, Paediatric Index of Emotional Distress, the HADS, Godin Leisure Time Exercise, Physical Activity Self Efficacy Scale, and Exercise Goal Setting Scale. The SDMT was administered in-person. Clinicians provided information on medication usage, episodes, and conducted a neurological exam. Neurocognitive batteries were conducted in-person. MRI and accelerometer data were also collected. Blood was collected for serum, DNA and PBMCs.