Harmonization Protocol / CANPATH-COVID19-F2-RESULTS-HP

CanPath COVID-19 Antibody Test Follow-up 2 - Serology Results Harmonization Protocol
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CanPath COVID-19 Antibody Test Follow-up 2 - Serology Results Harmonization Protocol

Networks -
Variables -
Version
1.0
Number of Participants
13,564
Approach
Prospective
Type
Quantitative
Procedures
Harmonized data is generated by a central harmonization team (with the collaboration of studies).
Participant Inclusion
All CanPath participants from cohorts collecting data on COVID-19 antibody test serology results at follow-up 2 are eligible.
Infrastructure
Harmonized data can be transferred to external servers, and pooled data analysis can be achieved.
Associated initiative CanPath-HI Contingency Table

Information Content

The COVID-19 Antibody Test Follow-up 2 - Serology Results Harmonization Protocol includes variables collected by the six CanPath population-based cohorts. The current dataset is the first release and includes information on more than 52,800 antibody test results (serology) for COVID-19. The harmonized dataset covers information on: * Sample type that was analyzed for serology * Date on which the ELISA assay was run. * Type of SARS-CoV-2 antigen tested for antibodies (anti-spike IgG, anti-receptor binding domain of spike (RBD) IgG, and anti-nucleocapsid (N) IgG)) * Serology results for each SARS-CoV-2 antigen

Studies Included

Study Population Data Collection Event
Atlantic PATH
ATP
BCGP
CaG
MTP
OHS

Initiatives Included

Harmonization

Complete - study-specific variable is the same as DataSchema variable (status detail = identical) or needs transformation to generate DataSchema variable (status detail = compatible)
Partial - categorical study-specific variable (status detail = proximate) or other types (status detail = tentative) could generate DataSchema variable but with loss of information
Impossible - study does not collect DataSchema variable (status detail = unavailable) or cannot be used to generate DataSchema variable (status detail = incompatible)
Undetermined - harmonization status not determined
Not Applicable - harmonization status is not relevant
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